American Heart Association
Top Clinical and Translational Abstracts in Vascular Medicine
Moderated Digital Poster Session
Clinical Science Zone 2, Moderated Digital Poster 21
Nov 9th , 11:50 AM - 01:05 PM
11 : 50 AM
Effects of Bempedoic Acid on Venous Thromboembolism: a Post-Hoc Analysis of The CLEAR Outcomes Trial
Spiazzi Bernardo, Brennan Danielle, Nissen Steven, Laffin Luke
Final Pr. ID: MP1718
Authors: Spiazzi Bernardo, Brennan Danielle, Nissen Steven, Laffin Luke
Keywords: Venous thrombosis , Pulmonary embolism , Lipids , LDL
11 : 57 AM
A Phase 2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Monthly or Quarterly Subcutaneous Administration of the Interleukin-6 Inhibitor Pacibekitug in Patients With Elevated High-Sensitivity C-Reactive Protein and Chronic Kidney Disease: 90-Day Analyses from TRANQUILITY
Pergola Pablo, Szarek Michael, Zayed Hany, Hemani Famina, Degoma Emil, Andorfer Cathy, Walsh John, Ridker Paul, Bhatt Deepak
Final Pr. ID: MP1719
Authors: Pergola Pablo, Szarek Michael, Zayed Hany, Hemani Famina, Degoma Emil, Andorfer Cathy, Walsh John, Ridker Paul, Bhatt Deepak
Keywords: Clinical trials , Cardiovascular disease
12 : 04 PM
Impact of Glucagon-Like Peptide-1 Receptor Agonists on 5-Year Risk of Major Amputation and Cardiovascular Outcomes in Diabetic Patients with Chronic Limb-Threatening Ischemia
Yahyavi Ashkan, Zokaei Nikoo Maedeh, Hussein Leen, Katara Aarti, Perez Jaime Abraham, Shishehbor Mehdi
Final Pr. ID: MP1720
Authors: Yahyavi Ashkan, Zokaei Nikoo Maedeh, Hussein Leen, Katara Aarti, Perez Jaime Abraham, Shishehbor Mehdi
Keywords: Peripheral artery disease (PAD) , Diabetes (Type II)
12 : 11 PM
Computational Modeling Predicts Benefits of Pro-efferocytic Therapy in Human Atherosclerosis
Jarr Kai-uwe, Palm Kaylin, Pasterkamp Gerard, Mokry Michal, Leeper Nicholas
Final Pr. ID: MP1721
Authors: Jarr Kai-uwe, Palm Kaylin, Pasterkamp Gerard, Mokry Michal, Leeper Nicholas
Keywords: Atherosclerosis , Plaque rupture
12 : 18 PM
The Role of Early Ezetimibe Combination with Atorvastatin in Patients with Atherosclerotic Cardiovascular Disease
Kang Si-hyuck, Kwon Sung Uk, Lee Jong-young, Seo Suk Min, Nam Chang-wook, Park Gyung-min, Hong Young Joon, Lee Won Young, Jang Jung Eun, Fitzgerald Nancy, Chae In-ho
Final Pr. ID: MP1722
Authors: Kang Si-hyuck, Kwon Sung Uk, Lee Jong-young, Seo Suk Min, Nam Chang-wook, Park Gyung-min, Hong Young Joon, Lee Won Young, Jang Jung Eun, Fitzgerald Nancy, Chae In-ho
Keywords: Lipids , Cardiovascular disease , Cardiovascular disease prevention , Cardiovascular therapeutics , Statins
12 : 25 PM
Effect Of Inclisiran-based Treatment Strategy, In Combination With Individually Optimized Statin Therapy, On Quality Of Life And Muscle-related Pain vs. Standard of Care: Exploratory Outcomes From The VICTORION-Difference Study
Landmesser Ulf, Laufs Ulrich, Schatz Ulrike, Winzer Ephraim, Nowak Bernd, Kassner Ursula, Gouni-berthold Ioanna, Esteban Alicia, Lubyayi Lawrence, Hentschke Christian, Achouba Assya, Banach Maciej
Final Pr. ID: MP1723
Authors: Landmesser Ulf, Laufs Ulrich, Schatz Ulrike, Winzer Ephraim, Nowak Bernd, Kassner Ursula, Gouni-berthold Ioanna, Esteban Alicia, Lubyayi Lawrence, Hentschke Christian, Achouba Assya, Banach Maciej
Keywords: Atherosclerosis , Cardiovascular disease , Quality of life
12 : 32 PM
Walking Impairment Questionnaire score declines after lower extremity revascularization are linked to adverse cardiovascular events and rivaroxaban dose not affect walking ability
Kim Byung Gyu, Patel Manesh, Debus Eike Sebastian, Nehler Mark, Anand Sonia, Hess Connie, Muehlhofer Eva, Haskell Lloyd, Berkowitz Scott, Bauersachs Rupert M, Bonaca Marc
Final Pr. ID: MP1724
Authors: Kim Byung Gyu, Patel Manesh, Debus Eike Sebastian, Nehler Mark, Anand Sonia, Hess Connie, Muehlhofer Eva, Haskell Lloyd, Berkowitz Scott, Bauersachs Rupert M, Bonaca Marc
Keywords: Peripheral artery disease (PAD) , Rivaroxaban , Quality assessment
12 : 39 PM
A First-In-Human Phase 1 Study of the Safety, Tolerability, and Pharmacodynamics of REGN7544, a Novel Natriuretic Peptide Receptor 1–Blocking Monoclonal Antibody
Ahmed Mohsin, Tuckwell Katie, Xu Meng, Cheng Xiping, Redington Emily, Koyani Bharatkumar, Mateo Katrina, Thakur Mazhar, Devalaraja-narashimha Kishor, Morton Lori, Olenchock Benjamin, Herman Gary, Wynne Chris, Marin Ethan
Final Pr. ID: MP1725
Authors: Ahmed Mohsin, Tuckwell Katie, Xu Meng, Cheng Xiping, Redington Emily, Koyani Bharatkumar, Mateo Katrina, Thakur Mazhar, Devalaraja-narashimha Kishor, Morton Lori, Olenchock Benjamin, Herman Gary, Wynne Chris, Marin Ethan
Keywords: Natriuretic peptide , Monoclonal antibodies , Clinical trials , Blood pressure
12 : 46 PM
Immunogenicity of Recaticimab Does Not Impact Its Efficacy in Patients with Dyslipidemia: A Pooled Analysis of Three Phase III and One Phase Ib/II Studies
Sun Yanyi, Chen Zhenyue
Final Pr. ID: MP1726
Authors: Sun Yanyi, Chen Zhenyue
Keywords: Cholesterol-lowering drugs , Dyslipidemia , PCSK9 , Antibodies , Efficacy
12 : 53 PM
Contemporary Management and Outcomes of Newly Diagnosed Chronic Limb Threatening Ischemia in the Veterans Affairs Health Care System
Tsai Shirling, Nguyen Cathy, Li Qiang, Modrall John, Banerjee Subhash, Beckman Joshua, Girotra Saket
Final Pr. ID: MP1727
Authors: Tsai Shirling, Nguyen Cathy, Li Qiang, Modrall John, Banerjee Subhash, Beckman Joshua, Girotra Saket
Keywords: Peripheral artery disease (PAD) , Outcomes
12 : 39 PM
A First-In-Human Phase 1 Study of the Safety, Tolerability, and Pharmacodynamics of REGN7544, a Novel Natriuretic Peptide Receptor 1–Blocking Monoclonal Antibody
Ahmed Mohsin, Tuckwell Katie, Xu Meng, Cheng Xiping, Redington Emily, Koyani Bharatkumar, Mateo Katrina, Thakur Mazhar, Devalaraja-narashimha Kishor, Morton Lori, Olenchock Benjamin, Herman Gary, Wynne Chris, Marin Ethan
Final Pr. ID: MP1725
Authors: Ahmed Mohsin, Tuckwell Katie, Xu Meng, Cheng Xiping, Redington Emily, Koyani Bharatkumar, Mateo Katrina, Thakur Mazhar, Devalaraja-narashimha Kishor, Morton Lori, Olenchock Benjamin, Herman Gary, Wynne Chris, Marin Ethan
Keywords: Natriuretic peptide , Monoclonal antibodies , Clinical trials , Blood pressure
11 : 57 AM
A Phase 2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Monthly or Quarterly Subcutaneous Administration of the Interleukin-6 Inhibitor Pacibekitug in Patients With Elevated High-Sensitivity C-Reactive Protein and Chronic Kidney Disease: 90-Day Analyses from TRANQUILITY
Pergola Pablo, Szarek Michael, Zayed Hany, Hemani Famina, Degoma Emil, Andorfer Cathy, Walsh John, Ridker Paul, Bhatt Deepak
Final Pr. ID: MP1719
Authors: Pergola Pablo, Szarek Michael, Zayed Hany, Hemani Famina, Degoma Emil, Andorfer Cathy, Walsh John, Ridker Paul, Bhatt Deepak
Keywords: Clinical trials , Cardiovascular disease
12 : 11 PM
Computational Modeling Predicts Benefits of Pro-efferocytic Therapy in Human Atherosclerosis
Jarr Kai-uwe, Palm Kaylin, Pasterkamp Gerard, Mokry Michal, Leeper Nicholas
Final Pr. ID: MP1721
Authors: Jarr Kai-uwe, Palm Kaylin, Pasterkamp Gerard, Mokry Michal, Leeper Nicholas
Keywords: Atherosclerosis , Plaque rupture
12 : 53 PM
Contemporary Management and Outcomes of Newly Diagnosed Chronic Limb Threatening Ischemia in the Veterans Affairs Health Care System
Tsai Shirling, Nguyen Cathy, Li Qiang, Modrall John, Banerjee Subhash, Beckman Joshua, Girotra Saket
Final Pr. ID: MP1727
Authors: Tsai Shirling, Nguyen Cathy, Li Qiang, Modrall John, Banerjee Subhash, Beckman Joshua, Girotra Saket
Keywords: Peripheral artery disease (PAD) , Outcomes
12 : 25 PM
Effect Of Inclisiran-based Treatment Strategy, In Combination With Individually Optimized Statin Therapy, On Quality Of Life And Muscle-related Pain vs. Standard of Care: Exploratory Outcomes From The VICTORION-Difference Study
Landmesser Ulf, Laufs Ulrich, Schatz Ulrike, Winzer Ephraim, Nowak Bernd, Kassner Ursula, Gouni-berthold Ioanna, Esteban Alicia, Lubyayi Lawrence, Hentschke Christian, Achouba Assya, Banach Maciej
Final Pr. ID: MP1723
Authors: Landmesser Ulf, Laufs Ulrich, Schatz Ulrike, Winzer Ephraim, Nowak Bernd, Kassner Ursula, Gouni-berthold Ioanna, Esteban Alicia, Lubyayi Lawrence, Hentschke Christian, Achouba Assya, Banach Maciej
Keywords: Atherosclerosis , Cardiovascular disease , Quality of life
11 : 50 AM
Effects of Bempedoic Acid on Venous Thromboembolism: a Post-Hoc Analysis of The CLEAR Outcomes Trial
Spiazzi Bernardo, Brennan Danielle, Nissen Steven, Laffin Luke
Final Pr. ID: MP1718
Authors: Spiazzi Bernardo, Brennan Danielle, Nissen Steven, Laffin Luke
Keywords: Venous thrombosis , Pulmonary embolism , Lipids , LDL
12 : 46 PM
Immunogenicity of Recaticimab Does Not Impact Its Efficacy in Patients with Dyslipidemia: A Pooled Analysis of Three Phase III and One Phase Ib/II Studies
Sun Yanyi, Chen Zhenyue
Final Pr. ID: MP1726
Authors: Sun Yanyi, Chen Zhenyue
Keywords: Cholesterol-lowering drugs , Dyslipidemia , PCSK9 , Antibodies , Efficacy
12 : 04 PM
Impact of Glucagon-Like Peptide-1 Receptor Agonists on 5-Year Risk of Major Amputation and Cardiovascular Outcomes in Diabetic Patients with Chronic Limb-Threatening Ischemia
Yahyavi Ashkan, Zokaei Nikoo Maedeh, Hussein Leen, Katara Aarti, Perez Jaime Abraham, Shishehbor Mehdi
Final Pr. ID: MP1720
Authors: Yahyavi Ashkan, Zokaei Nikoo Maedeh, Hussein Leen, Katara Aarti, Perez Jaime Abraham, Shishehbor Mehdi
Keywords: Peripheral artery disease (PAD) , Diabetes (Type II)
12 : 18 PM
The Role of Early Ezetimibe Combination with Atorvastatin in Patients with Atherosclerotic Cardiovascular Disease
Kang Si-hyuck, Kwon Sung Uk, Lee Jong-young, Seo Suk Min, Nam Chang-wook, Park Gyung-min, Hong Young Joon, Lee Won Young, Jang Jung Eun, Fitzgerald Nancy, Chae In-ho
Final Pr. ID: MP1722
Authors: Kang Si-hyuck, Kwon Sung Uk, Lee Jong-young, Seo Suk Min, Nam Chang-wook, Park Gyung-min, Hong Young Joon, Lee Won Young, Jang Jung Eun, Fitzgerald Nancy, Chae In-ho
Keywords: Lipids , Cardiovascular disease , Cardiovascular disease prevention , Cardiovascular therapeutics , Statins
12 : 32 PM
Walking Impairment Questionnaire score declines after lower extremity revascularization are linked to adverse cardiovascular events and rivaroxaban dose not affect walking ability
Kim Byung Gyu, Patel Manesh, Debus Eike Sebastian, Nehler Mark, Anand Sonia, Hess Connie, Muehlhofer Eva, Haskell Lloyd, Berkowitz Scott, Bauersachs Rupert M, Bonaca Marc
Final Pr. ID: MP1724
Authors: Kim Byung Gyu, Patel Manesh, Debus Eike Sebastian, Nehler Mark, Anand Sonia, Hess Connie, Muehlhofer Eva, Haskell Lloyd, Berkowitz Scott, Bauersachs Rupert M, Bonaca Marc
Keywords: Peripheral artery disease (PAD) , Rivaroxaban , Quality assessment