Showing Results from 1 to 12 of 175.
12 : 39 PM
A First-In-Human Phase 1 Study of the Safety, Tolerability, and Pharmacodynamics of REGN7544, a Novel Natriuretic Peptide Receptor 1–Blocking Monoclonal Antibody
Ahmed Mohsin, Morton Lori, Olenchock Benjamin, Herman Gary, Wynne Chris, Marin Ethan, Tuckwell Katie, Xu Meng, Cheng Xiping, Redington Emily, Koyani Bharatkumar, Mateo Katrina, Thakur Mazhar, Devalaraja-narashimha Kishor
Final Pr. ID: MP1725
Authors: Ahmed Mohsin , Morton Lori , Olenchock Benjamin , Herman Gary , Wynne Chris , Marin Ethan , Tuckwell Katie , Xu Meng , Cheng Xiping , Redington Emily , Koyani Bharatkumar , Mateo Katrina , Thakur Mazhar , Devalaraja-narashimha Kishor
Keywords: Natriuretic peptide, Monoclonal antibodies, Clinical trials, Blood pressure
07 : 00 PM
A Framework for Developing Prehospital Intracerebral Hemorrhage Recognition Scales and Technologies
Taleb Shayandokht, Hsu Jamie, Saver Jeffrey
Final Pr. ID: WP142
Authors: Taleb Shayandokht , Hsu Jamie , Saver Jeffrey
Keywords: Stroke emergency cerebrovascular care, Clinical trials, Intracranial hemorrhage, Emergency care, Blood pressure
03 : 30 PM
A Novel Thrombolytic with Anti-inflammatory Properties (JX10) Improves Neurological Outcomes in Acute Lacunar Infarct up to 12 hours After Onset
Chen Edmond, Niizuma Kuniyasu, Nitika Fnu, Hasumi Keiji, Tominaga Teiji, Nishimura Naoko, Zhang Shenglin
Final Pr. ID: 55
Authors: Chen Edmond , Niizuma Kuniyasu , Nitika Fnu , Hasumi Keiji , Tominaga Teiji , Nishimura Naoko , Zhang Shenglin
Keywords: Brain, Clinical trials, Stroke, Thrombolysis
11 : 57 AM
A Phase 2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Monthly or Quarterly Subcutaneous Administration of the Interleukin-6 Inhibitor Pacibekitug in Patients With Elevated High-Sensitivity C-Reactive Protein and Chronic Kidney Disease: 90-Day Analyses from TRANQUILITY
Pergola Pablo, Szarek Michael, Zayed Hany, Hemani Famina, Degoma Emil, Andorfer Cathy, Walsh John, Ridker Paul, Bhatt Deepak
Final Pr. ID: MP1719
Authors: Pergola Pablo , Szarek Michael , Zayed Hany , Hemani Famina , Degoma Emil , Andorfer Cathy , Walsh John , Ridker Paul , Bhatt Deepak
Keywords: Clinical trials, Cardiovascular disease
07 : 00 PM
A Phase 2 Study Evaluating the Effects of Mivelsiran, an Investigational RNA Interference Therapeutic, on Hemorrhagic and Nonhemorrhagic Manifestations of Cerebral Amyloid Angiopathy
Greenberg Steven, Parikh Neal, Lee Jin-moo, Van Etten Ellis, Van Osch Matthias, Klijn Catharina, Sostelly Alexandre, Goteti Sasikiran, Sepehrband Farshid, Avbersek Andreja, Deering Robert
Final Pr. ID: OGCTP8
Authors: Greenberg Steven , Parikh Neal , Lee Jin-moo , Van Etten Ellis , Van Osch Matthias , Klijn Catharina , Sostelly Alexandre , Goteti Sasikiran , Sepehrband Farshid , Avbersek Andreja , Deering Robert
Keywords: Amyloid angiopathy, Cerebrovascular disorders, Intracerebral hemorrhage, Stroke, Clinical trials
07 : 00 PM
A Phase 2a randomized controlled trial of once-daily versus twice-daily remote ischemic conditioning in vascular cognitive impairment (TRIC-VCI)
Ganesh Aravind, Mccreary Cheryl, Sahlas Demetrios, Sharma Mukul, Swartz Richard, Smith Eric, Barber Philip, Black Sandra, Corbett Dale, Field Thalia, Frayne Richard, Hachinski Vladimir, Ismail Zahinoor, Mai Lauren
Final Pr. ID: TP39
Authors: Ganesh Aravind , Mccreary Cheryl , Sahlas Demetrios , Sharma Mukul , Swartz Richard , Smith Eric , Barber Philip , Black Sandra , Corbett Dale , Field Thalia , Frayne Richard , Hachinski Vladimir , Ismail Zahinoor , Mai Lauren
Keywords: Cerebrovascular disorders, Cognitive impairment, Clinical trials, Vascular cognitive impairment, Device
03 : 50 PM
A Phase I, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of N-acetylgalactosamine Small Interfering RNA Conjugate, BPR-30221616, in Healthy Participants, for Potential Treatment of Transthyretin Amyloidosis
Han Xiaohong, Chen Rui, Cheng Xiwen, Zhang Langxi, Huang Haoxi, Fan Shengjun
Final Pr. ID: MP973
Authors: Han Xiaohong , Chen Rui , Cheng Xiwen , Zhang Langxi , Huang Haoxi , Fan Shengjun
Keywords: Amyloidosis, Cardiomyopathy, Clinical trials, Heart failure, Heart disease
09 : 45 AM
A Polypill Strategy for Lipid Lowering and Anti-Platelet Therapy After Acute Coronary Syndrome: A Pilot Randomized Controlled Trial
Keshvani Neil, Wang Thomas, Pandey Ambarish, Coellar Juan David, Rizvi Syed Kazim, Jain Anand, Bustillo-rubio M. Karina, Segar Matthew, Lokesh Nidhish, Miller James, Yates Sean
Final Pr. ID: 4369574
Authors: Keshvani Neil , Wang Thomas , Pandey Ambarish , Coellar Juan David , Rizvi Syed Kazim , Jain Anand , Bustillo-rubio M. Karina , Segar Matthew , Lokesh Nidhish , Miller James , Yates Sean
Keywords: Lipids, Antiplatelet drugs, Clinical trials, Acute coronary syndromes
08 : 30 AM
A Randomized Clinical Trial for Asymptomatic Elevated Blood Pressure in Patients Discharged from Emergency Department
Prendergast Heather, Khosla Shaveta, Kitsiou Spyros, Petzel Gimbar Renee, Freels Sally, Sanders Anissa, Daviglus Martha, Carter Barry, Del Rios Marina, Heinert Sara
Final Pr. ID: 27
Authors: Prendergast Heather , Khosla Shaveta , Kitsiou Spyros , Petzel Gimbar Renee , Freels Sally , Sanders Anissa , Daviglus Martha , Carter Barry , Del Rios Marina , Heinert Sara
Keywords: Hypertension, Intervention, Clinical trials, Disparities
03 : 15 PM
A Randomized Clinical Trial for Asymptomatic Elevated Blood Pressure in Patients Discharged from Emergency Department
Prendergast Heather, Khosla Shaveta, Kitsiou Spyros, Petzel Gimbar Renee, Freels Sally, Sanders Anissa, Daviglus Martha, Carter Barry, Del Rios Marina, Heinert Sara
Final Pr. ID: HTN11
Authors: Prendergast Heather , Khosla Shaveta , Kitsiou Spyros , Petzel Gimbar Renee , Freels Sally , Sanders Anissa , Daviglus Martha , Carter Barry , Del Rios Marina , Heinert Sara
Keywords: Hypertension, Clinical trials, Effectiveness
11 : 30 AM
A Randomized Comparison of Online Motivational Themes in Cardiovascular Clinical Trial Recruitment
Hussain Zaib, Harry Tamunotonye, Michos Erin, Milller Hailey, Juraschek Stephen, Turkson-ocran Ruth-alma, Lahey Timothy, Feng Yuanyuan, Plante Timothy
Final Pr. ID: 4357470
Authors: Hussain Zaib , Harry Tamunotonye , Michos Erin , Milller Hailey , Juraschek Stephen , Turkson-ocran Ruth-alma , Lahey Timothy , Feng Yuanyuan , Plante Timothy
Keywords: Digital Health, Cardiovascular, Clinical trials
12 : 27 PM
A randomized controlled trial of antithrombotic therapy in ischemic stroke patients with non-valvular atrial fibrillation and atherosclerosis: The ATIS-NVAF trial
Okazaki Shuhei, Uchida Kazutaka, Asakura Koko, Omae Katsuhiro, Yamamoto Haruko, Hirano Teruyuki, Toyoda Kazunori, Iguchi Yasuyuki, Noguchi Teruo, Okada Yasushi, Kitagawa Kazuo, Tanaka Kanta, Sakai Nobuyuki, Yamagami Hiroshi, Yazawa Yukako, Doijiri Ryosuke, Koga Masatoshi, Ihara Masafumi, Yamamoto Shiro, Kamiyama Kenji, Honda Yuko
Final Pr. ID: LB43
Authors: Okazaki Shuhei , Uchida Kazutaka , Asakura Koko , Omae Katsuhiro , Yamamoto Haruko , Hirano Teruyuki , Toyoda Kazunori , Iguchi Yasuyuki , Noguchi Teruo , Okada Yasushi , Kitagawa Kazuo , Tanaka Kanta , Sakai Nobuyuki , Yamagami Hiroshi , Yazawa Yukako , Doijiri Ryosuke , Koga Masatoshi , Ihara Masafumi , Yamamoto Shiro , Kamiyama Kenji , Honda Yuko
Keywords: Anticoagulants, Antiplatelet drugs, Atrial fibrillation, Atherosclerosis, Clinical trials