Showing Results from 1 to 12 of 35.
07 : 30 AM
A First-in-Class Humanized Antibody Fragment Targeting Platelet Glycoprotein Ibα: A Comprehensive Preclinical Study of CA1001 for the Treatment of Acute Ischemic Stroke
Xu Xiaohong, Preeti Preeti, Yu Ruoying, Shaykhalishahi Hamed, Zhang Cheng, Shen Chuanbin, Li Bei, Tang Naping, Chang Yan, Xiang Qian, Cui Yimin, Lei Xi, Ni Heyu, Zhu Guangheng, Liu Zhenze, Hu Xudong, Slavkovic Sladjana, Neves Miguel, Ma Wenjing, Xie Huifang
Final Pr. ID: 89
Authors: Xu Xiaohong , Preeti Preeti , Yu Ruoying , Shaykhalishahi Hamed , Zhang Cheng , Shen Chuanbin , Li Bei , Tang Naping , Chang Yan , Xiang Qian , Cui Yimin , Lei Xi , Ni Heyu , Zhu Guangheng , Liu Zhenze , Hu Xudong , Slavkovic Sladjana , Neves Miguel , Ma Wenjing , Xie Huifang
Keywords: Ischemic stroke, Reperfusion injury, Antithrombotic therapy, Pharmacology, Antibodies
12 : 39 PM
A First-In-Human Phase 1 Study of the Safety, Tolerability, and Pharmacodynamics of REGN7544, a Novel Natriuretic Peptide Receptor 1–Blocking Monoclonal Antibody
Ahmed Mohsin, Morton Lori, Olenchock Benjamin, Herman Gary, Wynne Chris, Marin Ethan, Tuckwell Katie, Xu Meng, Cheng Xiping, Redington Emily, Koyani Bharatkumar, Mateo Katrina, Thakur Mazhar, Devalaraja-narashimha Kishor
Final Pr. ID: MP1725
Authors: Ahmed Mohsin , Morton Lori , Olenchock Benjamin , Herman Gary , Wynne Chris , Marin Ethan , Tuckwell Katie , Xu Meng , Cheng Xiping , Redington Emily , Koyani Bharatkumar , Mateo Katrina , Thakur Mazhar , Devalaraja-narashimha Kishor
Keywords: Natriuretic peptide, Monoclonal antibodies, Clinical trials, Blood pressure
03 : 15 PM
ANGPTL3 Targeting Monoclonal Antibodies Lead to Robust Reductions in LDL-C, Triglycerides, ApoB, and Non-HDL-C in Dyslipidemic Patients: A Meta-Analysis of 5 Randomized Controlled Trials
Daid Simranpreet Singh, Sharma Anubhuti, Sharma Arundhati, Pannu Sagal, Asnani Heena, Bhanushali Karan, Choudhary Khushal, Sharma Saurabh
Final Pr. ID: Su2130
Authors: Daid Simranpreet Singh , Sharma Anubhuti , Sharma Arundhati , Pannu Sagal , Asnani Heena , Bhanushali Karan , Choudhary Khushal , Sharma Saurabh
Keywords: LDL, Cholesterol-lowering drugs, Dyslipidemia, Monoclonal antibodies, Hypercholesterolemia
11 : 34 AM
Association Between Antiphospholipid Antibody and Ischemic Stroke: A Systematic Review and Meta-Analysis
Watson Nathan, Kanthi Yogen, Secemsky Eric, Connors Jean, Barnes Geoffrey, Goldhaber Samuel, Weitz Jeffrey, Costenbader Karen, Piazza Gregory, Krumholz Harlan, Cushman Mary, Bukhari Syed, Bikdeli Behnood, Rashedi Sina, Weber Brittany, Anderson Christopher, Elkind Mitchell, Pfeferman Mariana, Ujueta Francisco, Zarghami Mehrdad
Final Pr. ID: MP2103
Authors: Watson Nathan , Kanthi Yogen , Secemsky Eric , Connors Jean , Barnes Geoffrey , Goldhaber Samuel , Weitz Jeffrey , Costenbader Karen , Piazza Gregory , Krumholz Harlan , Cushman Mary , Bukhari Syed , Bikdeli Behnood , Rashedi Sina , Weber Brittany , Anderson Christopher , Elkind Mitchell , Pfeferman Mariana , Ujueta Francisco , Zarghami Mehrdad
Keywords: Antibodies, Ischemic stroke, Stroke, Thrombosis, Cerebrovascular disorders
05 : 00 PM
Association of Demographic and Clinical Factors with SARS-CoV-2 Anti-Nucleocapsid Antibody Response Among Previously Infected US Adults: The C4R Study
Demmer Ryan, Bell Taison, Anderson Michaela, Allen Norrina, Schreiner Pamela, Bowler Russell, Schwartz David, Lee Joyce, Xanthakis Vanessa, Rock Jean, Bievenue Rachel, Wu Chaoqi, Pirzada Amber, Doyle Margaret, Regan Elizabeth, Make Barry, Kanaya Alka, Kandula Namratha, Morganroth S, Coresh Joe, Isasi Carmen, Raffield Laura, Kim John, Elkind Mitchell, Howard Virginia, Ortega Victor, Woodruff Prescott, Cole Shelley, Henderson Joel, Mantis Nicholas, Oelsner Elizabeth, Sun Yifei, Balte Pallavi, Cushman Mary, Boyle Rebekah, Tracy Russell, Styer Linda
Final Pr. ID: P1063
Authors: Demmer Ryan , Bell Taison , Anderson Michaela , Allen Norrina , Schreiner Pamela , Bowler Russell , Schwartz David , Lee Joyce , Xanthakis Vanessa , Rock Jean , Bievenue Rachel , Wu Chaoqi , Pirzada Amber , Doyle Margaret , Regan Elizabeth , Make Barry , Kanaya Alka , Kandula Namratha , Morganroth S , Coresh Joe , Isasi Carmen , Raffield Laura , Kim John , Elkind Mitchell , Howard Virginia , Ortega Victor , Woodruff Prescott , Cole Shelley , Henderson Joel , Mantis Nicholas , Oelsner Elizabeth , Sun Yifei , Balte Pallavi , Cushman Mary , Boyle Rebekah , Tracy Russell , Styer Linda
Keywords: Infection, Infectious Diseases, Antibodies, Immunology, Risk Factors
03 : 15 PM
Blocking ANTXR1 in Cardiac Fibroblasts Alleviates Heart Failure in Mice via the TGF-β Pathway
Yu Guojun, Boccella Nicola, Seaman Steven, Feng Yang, Tessarollo Lino, St Croix Bradley
Final Pr. ID: LBMP13
Authors: Yu Guojun , Boccella Nicola , Seaman Steven , Feng Yang , Tessarollo Lino , St Croix Bradley
Keywords: Fibrosis, Antibodies, Cardiovascular therapeutics, Myocardial infarction, Hypertension
12 : 39 PM
CAR-T Therapies Associated with Higher CRS-Linked Cardiotoxicity Signal than BiTE Agents in Multiple Myeloma: Analysis of Adverse Event Report
Tangella Adarshvardhan, Ayyalu Tanesh, Spahr Zachary, Taylor Allen
Final Pr. ID: MP1667
Authors: Tangella Adarshvardhan , Ayyalu Tanesh , Spahr Zachary , Taylor Allen
Keywords: Cardio-oncology, Cardiomyopathy, Monoclonal antibodies
Akbar Usman, Naveed Muhammad Abdullah, Khan Muhammad Aslam, Cheshire Michael, Umer Ahmed Muaaz, Muhibullah Fnu, Shafique Nouman, Ali Sarmad, Naseer Faisal, Nawaz Hassan, Lohana Abhi, Ahmed Faizan
Final Pr. ID: Sa1111
Authors: Akbar Usman , Naveed Muhammad Abdullah , Khan Muhammad Aslam , Cheshire Michael , Umer Ahmed Muaaz , Muhibullah Fnu , Shafique Nouman , Ali Sarmad , Naseer Faisal , Nawaz Hassan , Lohana Abhi , Ahmed Faizan
Keywords: Vasculitis brain arteries, Arteries, Antibodies
02 : 00 PM
CD40 is an immune checkpoint regulator that potentiates myocardial inflammation through activation and expansion of CCR2 macrophages and CD8 T-cells
Jimenez Jesus, Amrute Junedh, Ma Pan, Wang Xiaoran, Dai Raymond, Lavine Kory
Final Pr. ID: BCVS7
Authors: Jimenez Jesus , Amrute Junedh , Ma Pan , Wang Xiaoran , Dai Raymond , Lavine Kory
Keywords: Cardio-oncology, Inflammation and inflammatory markers, Immunosuppressive therapy, Myocarditis, Monoclonal antibodies
Jin Xuyan, Sasaki Yuichi, Zhai Qingling, Ayata Cenk
Final Pr. ID: TP391
Authors: Jin Xuyan , Sasaki Yuichi , Zhai Qingling , Ayata Cenk
Keywords: Ischemic stroke, Stroke, Antibodies, Infarct size, Vascular disease
Sun Yin, Huang Yuhsin, Chou Harrison, Vitale Maria Rosaria, Lin Zachary, Zhu Han
Final Pr. ID: Mo017
Authors: Sun Yin , Huang Yuhsin , Chou Harrison , Vitale Maria Rosaria , Lin Zachary , Zhu Han
Keywords: Myocarditis, Monoclonal antibodies, Cardio-oncology, Targeted therapeutics
12 : 53 PM
Does Knowledge of Anti-Ro Antibody Status Before Pregnancy Affect Diagnosis of Fetal Cardiac Neonatal Lupus? A Fetal Heart Society Research Collaborative Study
Kaplinski Michelle, Krishnan Anita, Hogan Whitnee, Sharma Kavita, Ikemba Catherine, Levasseur Stephanie, Owens Sonal, Deweert Katherine, Kohari Katherine, Copel Joshua, Bucholz Emily, Kaizer Alexander, Gilbert Lisa, Srinivasan Shardha, Samples Stefani, Patel Angira, Phoon Colin, Srinivasan Ranjini, Mcintosh Amanda, Kiaffas Maria, Geiger Miwa, Mcfarland Carol, Cuneo Bettina, Pinto Nelangi, Arya Bhawna, Doan Tam, Moreno Jamine, Lindblade Chris, Gropler Melanie, Buyon Jill, Killen Stacy, Moon-grady Anita, Nunez Gallegos Flora, Hornberger Lisa, Howley Lisa, Paul Erin, Donofrio Mary
Final Pr. ID: MP1610
Authors: Kaplinski Michelle , Krishnan Anita , Hogan Whitnee , Sharma Kavita , Ikemba Catherine , Levasseur Stephanie , Owens Sonal , Deweert Katherine , Kohari Katherine , Copel Joshua , Bucholz Emily , Kaizer Alexander , Gilbert Lisa , Srinivasan Shardha , Samples Stefani , Patel Angira , Phoon Colin , Srinivasan Ranjini , Mcintosh Amanda , Kiaffas Maria , Geiger Miwa , Mcfarland Carol , Cuneo Bettina , Pinto Nelangi , Arya Bhawna , Doan Tam , Moreno Jamine , Lindblade Chris , Gropler Melanie , Buyon Jill , Killen Stacy , Moon-grady Anita , Nunez Gallegos Flora , Hornberger Lisa , Howley Lisa , Paul Erin , Donofrio Mary
Keywords: Fetal imaging, Antibodies, Autoimmune, Heart block