Showing Results from 1 to 12 of 36.
07 : 30 AM
A First-in-Class Humanized Antibody Fragment Targeting Platelet Glycoprotein Ibα: A Comprehensive Preclinical Study of CA1001 for the Treatment of Acute Ischemic Stroke
Xu Xiaohong, Lei Xi, Zhu Guangheng, Liu Zhenze, Hu Xudong, Slavkovic Sladjana, Neves Miguel, Ma Wenjing, Xie Huifang, Preeti Preeti, Yu Ruoying, Shaykhalishahi Hamed, Zhang Cheng, Shen Chuanbin, Li Bei, Tang Naping, Chang Yan, Xiang Qian, Cui Yimin, Ni Heyu
Final Pr. ID: 89
Authors: Xu Xiaohong, Lei Xi, Zhu Guangheng, Liu Zhenze, Hu Xudong, Slavkovic Sladjana, Neves Miguel, Ma Wenjing, Xie Huifang, Preeti Preeti, Yu Ruoying, Shaykhalishahi Hamed, Zhang Cheng, Shen Chuanbin, Li Bei, Tang Naping, Chang Yan, Xiang Qian, Cui Yimin, Ni Heyu
Keywords: Ischemic stroke, Reperfusion injury, Antithrombotic therapy, Pharmacology, Antibodies
12 : 39 PM
A First-In-Human Phase 1 Study of the Safety, Tolerability, and Pharmacodynamics of REGN7544, a Novel Natriuretic Peptide Receptor 1–Blocking Monoclonal Antibody
Ahmed Mohsin, Tuckwell Katie, Xu Meng, Cheng Xiping, Redington Emily, Koyani Bharatkumar, Mateo Katrina, Thakur Mazhar, Devalaraja-narashimha Kishor, Morton Lori, Olenchock Benjamin, Herman Gary, Wynne Chris, Marin Ethan
Final Pr. ID: MP1725
Authors: Ahmed Mohsin, Tuckwell Katie, Xu Meng, Cheng Xiping, Redington Emily, Koyani Bharatkumar, Mateo Katrina, Thakur Mazhar, Devalaraja-narashimha Kishor, Morton Lori, Olenchock Benjamin, Herman Gary, Wynne Chris, Marin Ethan
Keywords: Natriuretic peptide, Monoclonal antibodies, Clinical trials, Blood pressure
03 : 15 PM
ANGPTL3 Targeting Monoclonal Antibodies Lead to Robust Reductions in LDL-C, Triglycerides, ApoB, and Non-HDL-C in Dyslipidemic Patients: A Meta-Analysis of 5 Randomized Controlled Trials
Daid Simranpreet Singh, Sharma Anubhuti, Sharma Arundhati, Pannu Sagal, Asnani Heena, Bhanushali Karan, Choudhary Khushal, Sharma Saurabh
Final Pr. ID: Su2130
Authors: Daid Simranpreet Singh, Sharma Anubhuti, Sharma Arundhati, Pannu Sagal, Asnani Heena, Bhanushali Karan, Choudhary Khushal, Sharma Saurabh
Keywords: LDL, Cholesterol-lowering drugs, Dyslipidemia, Monoclonal antibodies, Hypercholesterolemia
05 : 00 PM
Anti-Oxidized Phospholipid Antibody Prevents Immune Cell Priming and the Acceleration of Atherosclerotic Plaque Inflammation during Plasma LDL Cholesterol Cycling
La Forest Maxwell, Li Zhixing, Weinstock Ada, Scolaro Bianca, Que Xuchu, Krautter Franziska, Laskou Maria, Tsimikas Sotirios, Goldberg Ira, Giannarelli Chiara, Berger Jeffrey, Witztum Joseph, Ruggles Kelly, Fisher Edward
Final Pr. ID: Thu061
Authors: La Forest Maxwell, Li Zhixing, Weinstock Ada, Scolaro Bianca, Que Xuchu, Krautter Franziska, Laskou Maria, Tsimikas Sotirios, Goldberg Ira, Giannarelli Chiara, Berger Jeffrey, Witztum Joseph, Ruggles Kelly, Fisher Edward
Keywords: Arteriosclerosis, Antibodies, Inflammation, Cholesterol
11 : 34 AM
Association Between Antiphospholipid Antibody and Ischemic Stroke: A Systematic Review and Meta-Analysis
Watson Nathan, Bukhari Syed, Rashedi Sina, Weber Brittany, Anderson Christopher, Elkind Mitchell, Pfeferman Mariana, Ujueta Francisco, Zarghami Mehrdad, Kanthi Yogen, Secemsky Eric, Connors Jean, Barnes Geoffrey, Goldhaber Samuel, Weitz Jeffrey, Costenbader Karen, Piazza Gregory, Krumholz Harlan, Cushman Mary, Bikdeli Behnood
Final Pr. ID: MP2103
Authors: Watson Nathan, Bukhari Syed, Rashedi Sina, Weber Brittany, Anderson Christopher, Elkind Mitchell, Pfeferman Mariana, Ujueta Francisco, Zarghami Mehrdad, Kanthi Yogen, Secemsky Eric, Connors Jean, Barnes Geoffrey, Goldhaber Samuel, Weitz Jeffrey, Costenbader Karen, Piazza Gregory, Krumholz Harlan, Cushman Mary, Bikdeli Behnood
Keywords: Antibodies, Ischemic stroke, Stroke, Thrombosis, Cerebrovascular disorders
05 : 00 PM
Association of Demographic and Clinical Factors with SARS-CoV-2 Anti-Nucleocapsid Antibody Response Among Previously Infected US Adults: The C4R Study
Demmer Ryan, Wu Chaoqi, Kim John, Sun Yifei, Balte Pallavi, Cushman Mary, Boyle Rebekah, Tracy Russell, Styer Linda, Bell Taison, Anderson Michaela, Allen Norrina, Schreiner Pamela, Bowler Russell, Schwartz David, Lee Joyce, Xanthakis Vanessa, Rock Jean, Bievenue Rachel, Pirzada Amber, Doyle Margaret, Regan Elizabeth, Make Barry, Kanaya Alka, Kandula Namratha, Morganroth S, Coresh Joe, Isasi Carmen, Raffield Laura, Elkind Mitchell, Howard Virginia, Ortega Victor, Woodruff Prescott, Cole Shelley, Henderson Joel, Mantis Nicholas, Oelsner Elizabeth
Final Pr. ID: P1063
Authors: Demmer Ryan, Wu Chaoqi, Kim John, Sun Yifei, Balte Pallavi, Cushman Mary, Boyle Rebekah, Tracy Russell, Styer Linda, Bell Taison, Anderson Michaela, Allen Norrina, Schreiner Pamela, Bowler Russell, Schwartz David, Lee Joyce, Xanthakis Vanessa, Rock Jean, Bievenue Rachel, Pirzada Amber, Doyle Margaret, Regan Elizabeth, Make Barry, Kanaya Alka, Kandula Namratha, Morganroth S, Coresh Joe, Isasi Carmen, Raffield Laura, Elkind Mitchell, Howard Virginia, Ortega Victor, Woodruff Prescott, Cole Shelley, Henderson Joel, Mantis Nicholas, Oelsner Elizabeth
Keywords: Infection, Infectious Diseases, Antibodies, Immunology, Risk Factors
03 : 15 PM
Blocking ANTXR1 in Cardiac Fibroblasts Alleviates Heart Failure in Mice via the TGF-β Pathway
Yu Guojun, Boccella Nicola, Seaman Steven, Feng Yang, Tessarollo Lino, St Croix Bradley
Final Pr. ID: LBMP13
Authors: Yu Guojun, Boccella Nicola, Seaman Steven, Feng Yang, Tessarollo Lino, St Croix Bradley
Keywords: Fibrosis, Antibodies, Cardiovascular therapeutics, Myocardial infarction, Hypertension
12 : 39 PM
CAR-T Therapies Associated with Higher CRS-Linked Cardiotoxicity Signal than BiTE Agents in Multiple Myeloma: Analysis of Adverse Event Report
Tangella Adarshvardhan, Ayyalu Tanesh, Spahr Zachary, Taylor Allen
Final Pr. ID: MP1667
Authors: Tangella Adarshvardhan, Ayyalu Tanesh, Spahr Zachary, Taylor Allen
Keywords: Cardio-oncology, Cardiomyopathy, Monoclonal antibodies
Akbar Usman, Umer Ahmed Muaaz, Muhibullah Fnu, Shafique Nouman, Ali Sarmad, Naseer Faisal, Nawaz Hassan, Lohana Abhi, Ahmed Faizan, Naveed Muhammad Abdullah, Khan Muhammad Aslam, Cheshire Michael
Final Pr. ID: Sa1111
Authors: Akbar Usman, Umer Ahmed Muaaz, Muhibullah Fnu, Shafique Nouman, Ali Sarmad, Naseer Faisal, Nawaz Hassan, Lohana Abhi, Ahmed Faizan, Naveed Muhammad Abdullah, Khan Muhammad Aslam, Cheshire Michael
Keywords: Vasculitis brain arteries, Arteries, Antibodies
02 : 00 PM
CD40 is an immune checkpoint regulator that potentiates myocardial inflammation through activation and expansion of CCR2 macrophages and CD8 T-cells
Jimenez Jesus, Amrute Junedh, Ma Pan, Wang Xiaoran, Dai Raymond, Lavine Kory
Final Pr. ID: BCVS7
Authors: Jimenez Jesus, Amrute Junedh, Ma Pan, Wang Xiaoran, Dai Raymond, Lavine Kory
Keywords: Cardio-oncology, Inflammation and inflammatory markers, Immunosuppressive therapy, Myocarditis, Monoclonal antibodies
Jin Xuyan, Sasaki Yuichi, Zhai Qingling, Ayata Cenk
Final Pr. ID: TP391
Authors: Jin Xuyan, Sasaki Yuichi, Zhai Qingling, Ayata Cenk
Keywords: Ischemic stroke, Stroke, Antibodies, Infarct size, Vascular disease
Sun Yin, Huang Yuhsin, Chou Harrison, Vitale Maria Rosaria, Lin Zachary, Zhu Han
Final Pr. ID: Mo017
Authors: Sun Yin, Huang Yuhsin, Chou Harrison, Vitale Maria Rosaria, Lin Zachary, Zhu Han
Keywords: Myocarditis, Monoclonal antibodies, Cardio-oncology, Targeted therapeutics