Showing Results from 1 to 12 of 55.
01 : 30 PM
A Novel CRISPR based Epigenetic Silencer Potently, Durably, and Safely Reduces LDLc in Non-Human Primates at Therapeutically Relevant Doses
Duncan-lewis Christopher, Narsineni Lokesh, Karmarkar Maitreyee, Li Yuexuan, Krupa Oleh, Bucher Simon, Sharma Neel, Chang Han, Schulwach Keith, Ripley-phipps Sterling, Tran Vanessa, Fernandes Jason, Goh Natalie, Deiter Fred, Reimer Kirsten, Mrak Anna, Eggers Michelle, Sze Christie, Mirotsou Maria, Oresic Bender Kristina, Bardai Farah, Denny Sarah, Charles Emeric, Khakoo Aarif, Oakes Benjamin, Keller Steven, Alcantara-lee Raniel, Santamaria Carlos, Bale Shyam Sundhar, Kozy Heather, Corbo Lana
Final Pr. ID: 4172282
Authors: Duncan-lewis Christopher , Narsineni Lokesh , Karmarkar Maitreyee , Li Yuexuan , Krupa Oleh , Bucher Simon , Sharma Neel , Chang Han , Schulwach Keith , Ripley-phipps Sterling , Tran Vanessa , Fernandes Jason , Goh Natalie , Deiter Fred , Reimer Kirsten , Mrak Anna , Eggers Michelle , Sze Christie , Mirotsou Maria , Oresic Bender Kristina , Bardai Farah , Denny Sarah , Charles Emeric , Khakoo Aarif , Oakes Benjamin , Keller Steven , Alcantara-lee Raniel , Santamaria Carlos , Bale Shyam Sundhar , Kozy Heather , Corbo Lana
Keywords: Epigenetics, Cholesterol-lowering drugs, Cardiovascular disease, PCSK9, LDL
11 : 10 AM
A Novel RNA Interference Agent RN0191 Lowering Proprotein Convertase Subtilisin/Kexin Type 9, Low-density Lipoprotein Cholesterol and Other Lipid Biomarkers in Healthy Volunteers with Elevated LDL Cholesterol: A Randomized, Single-blind, Placebo-controlled, Phase 1 Trial
Wang Fangfang, Li Haiyan, Zeng Jie, Shi Yibin, Li Hongmei
Final Pr. ID: MDP463
Authors: Wang Fangfang , Li Haiyan , Zeng Jie , Shi Yibin , Li Hongmei
Keywords: PCSK9, LDL, Coronary artery disease
10 : 30 AM
Atherosclerotic Cardiovascular Disease Risk Management in a Primary Care Residency Clinic
Manalo Kathryn, Tieliwaerdi Xiarepati, Jackson Megan, Arrigo Alexis, Mascara Mariah, Maharjan Srijana, Gadani Mrudula
Final Pr. ID: Sa3112
Authors: Manalo Kathryn , Tieliwaerdi Xiarepati , Jackson Megan , Arrigo Alexis , Mascara Mariah , Maharjan Srijana , Gadani Mrudula
Keywords: LDL, Statins, Prevention, PCSK9, Guidelines
04 : 30 PM
Base editing approach to limit the expression of Asgr1, Pcsk9 and Angptl3 for the control of hyperlipidemia in mice
Agrahari Gaurav
Final Pr. ID: Thu095
Authors: Agrahari Gaurav
Keywords: Atherosclerosis, Cholesterol, Lipids, PCSK9, Gene mutations
10 : 15 AM
Changes in Lipoprotein(a) and Oxidized Phospholipids Are Associated with Myocardial Inflammation but Not Systemic Inflammatory Markers Following an Acute Myocardial Infarction
Atallah Mark, Nasrallah Nadim, Harb Tarek, Valenta Ines, Schindler Thomas, Wallace Amelia, Tsimikas Sotirios, Gerstenblith Gary, Leucker Thorsten
Final Pr. ID: 4360857
Authors: Atallah Mark , Nasrallah Nadim , Harb Tarek , Valenta Ines , Schindler Thomas , Wallace Amelia , Tsimikas Sotirios , Gerstenblith Gary , Leucker Thorsten
Keywords: Acute coronary syndromes, Oxidized lipids, Lipoproteins, PCSK9
01 : 00 PM
Circulating PCSK9 as an Independent Prognostic Marker in High-Risk Coronary Multi-Vessel Disease: Evidence from a Multicenter Cohort Study
Yan Kailun, Li Jiawen, Zhang Kexin, Liu Menglu, Yuan Jinqing, Zhao Xueyan
Final Pr. ID: Mo3058
Authors: Yan Kailun , Li Jiawen , Zhang Kexin , Liu Menglu , Yuan Jinqing , Zhao Xueyan
Keywords: PCSK9, Coronary artery disease, Biomarkers, Percutaneous coronary intervention (PCI), Outcomes
02 : 00 PM
Clinical characteristics and treatment of high-risk cardiovascular patients without prior myocardial infarction or stroke: VESALIUS-REAL - results from US
Chan Queenie, Jernberg Tomas, Cegla Jaimini, Budoff Matthew, Wong Ian, Sakhuja Swati, Ochs Andreas, Dhalwani Nafeesa, O'kelly James, Shannon Erin, Paivadasilva Lima Gabriel, Avcil Suna, Laufs Ulrich
Final Pr. ID: Sa3109
Authors: Chan Queenie , Jernberg Tomas , Cegla Jaimini , Budoff Matthew , Wong Ian , Sakhuja Swati , Ochs Andreas , Dhalwani Nafeesa , O'kelly James , Shannon Erin , Paivadasilva Lima Gabriel , Avcil Suna , Laufs Ulrich
Keywords: Epidemiology, Cardiovascular Risk, LDL, PCSK9, Statins
03 : 10 PM
Comparison of Lipoprotein(a) and Other Apo B Containing Lipoproteins as Predictors of Major Adverse Cardiovascular Events in ODYSSEY OUTCOMES
Bittner Vera, Goodman Shaun, Harrington Robert, White Harvey, Zeiher Andreas, Cobbaert Christa, Schwartz Gregory, Szarek Michael, Steg Philippe, Jukema J, Reijnders Esther, Bhatt Deepak, Diaz Rafael, Fazio Sergio, Garon Genevieve
Final Pr. ID: MDP601
Authors: Bittner Vera , Goodman Shaun , Harrington Robert , White Harvey , Zeiher Andreas , Cobbaert Christa , Schwartz Gregory , Szarek Michael , Steg Philippe , Jukema J , Reijnders Esther , Bhatt Deepak , Diaz Rafael , Fazio Sergio , Garon Genevieve
Keywords: Lipoproteins, Acute coronary syndromes, PCSK9, Apolipoproteins, Prognosis
Kohli-lynch Ciaran, Bellows Brandon, Moran Andrew, Zhang Yiyi, Wilkins John, Lloyd-jones Donald
Final Pr. ID: EPI6
Authors: Kohli-lynch Ciaran , Bellows Brandon , Moran Andrew , Zhang Yiyi , Wilkins John , Lloyd-jones Donald
Keywords: Cost-effectiveness, Lipids, PCSK9, Statins
05 : 00 PM
Cysteinyl Leukotriene Receptors Modulate Macrophage-Endothelial Cell Crosstalk and Atherosclerosis Progression
Darzi Somayeh, Teegala Lakshminarayan Reddy, Sabu Kattuman Emma Elizabeth, Thodeti Charles, Paruchuri Sailaja
Final Pr. ID: We0068
Authors: Darzi Somayeh , Teegala Lakshminarayan Reddy , Sabu Kattuman Emma Elizabeth , Thodeti Charles , Paruchuri Sailaja
Keywords: Arteriosclerosis, PCSK9, Inflammation, Molecular biology
01 : 52 PM
Discontinuation of PCSK9 Inhibitor Therapy and Its Impact on Cardiovascular Outcomes in a Japanese Cohort
Tsubata Hideo, Nakanishi Naohiko, Matoba Satoaki
Final Pr. ID: MP629
Authors: Tsubata Hideo , Nakanishi Naohiko , Matoba Satoaki
Keywords: PCSK9, Cardiovascular disease prevention, Adherence, Coronary artery disease
09 : 10 AM
Effect of Evolocumab in Patients at High Cardiovascular Risk without Prior Myocardial Infarction or Stroke: Primary Results of the VESALIUS-CV trial
Bohula Erin, Wang Huei, Cyrille Marcoli, Paiva Da Silva Lima Gabriel, Giugliano Robert, Sabatine Marc, Marston Nicholas, Bhatia Ajay, De Ferrari Gaetano Maria, Leiter Lawrence, Nicolau Jose, Park Jeong-gun, Murphy Sabina, Walsh Emileigh
Final Pr. ID: -
Authors: Bohula Erin , Wang Huei , Cyrille Marcoli , Paiva Da Silva Lima Gabriel , Giugliano Robert , Sabatine Marc , Marston Nicholas , Bhatia Ajay , De Ferrari Gaetano Maria , Leiter Lawrence , Nicolau Jose , Park Jeong-gun , Murphy Sabina , Walsh Emileigh
Keywords: Apolipoproteins, Lipids, PCSK9, Outcomes, Lipoproteins