Showing Results from 1 to 12 of 48.
02 : 00 PM
4-Phenylbutyric Acid Reduces Endoplasmic Reticulum Retention and Partially Restores Function of LDLR p.D622N Mutation In Vitro: A Potential Therapy for Hypercholesterolemia
Wang Yongxiang, Zhang Piyi, Bai Ming, Zhang Zheng
Final Pr. ID: Sa1098
Authors: Wang Yongxiang , Zhang Piyi , Bai Ming , Zhang Zheng
Keywords: Hyperlipoproteinemia, Gene mutations, Family, Cholesterol-lowering drugs, Genetics
01 : 30 PM
A Novel CRISPR based Epigenetic Silencer Potently, Durably, and Safely Reduces LDLc in Non-Human Primates at Therapeutically Relevant Doses
Duncan-lewis Christopher, Narsineni Lokesh, Karmarkar Maitreyee, Li Yuexuan, Krupa Oleh, Bucher Simon, Sharma Neel, Chang Han, Schulwach Keith, Ripley-phipps Sterling, Tran Vanessa, Fernandes Jason, Goh Natalie, Deiter Fred, Reimer Kirsten, Mrak Anna, Eggers Michelle, Sze Christie, Mirotsou Maria, Oresic Bender Kristina, Bardai Farah, Denny Sarah, Charles Emeric, Khakoo Aarif, Oakes Benjamin, Keller Steven, Alcantara-lee Raniel, Santamaria Carlos, Bale Shyam Sundhar, Kozy Heather, Corbo Lana
Final Pr. ID: 4172282
Authors: Duncan-lewis Christopher , Narsineni Lokesh , Karmarkar Maitreyee , Li Yuexuan , Krupa Oleh , Bucher Simon , Sharma Neel , Chang Han , Schulwach Keith , Ripley-phipps Sterling , Tran Vanessa , Fernandes Jason , Goh Natalie , Deiter Fred , Reimer Kirsten , Mrak Anna , Eggers Michelle , Sze Christie , Mirotsou Maria , Oresic Bender Kristina , Bardai Farah , Denny Sarah , Charles Emeric , Khakoo Aarif , Oakes Benjamin , Keller Steven , Alcantara-lee Raniel , Santamaria Carlos , Bale Shyam Sundhar , Kozy Heather , Corbo Lana
Keywords: Epigenetics, Cholesterol-lowering drugs, Cardiovascular disease, PCSK9, LDL
11 : 06 AM
A transformative LDL cholesterol–lowering in vivo CRISPR gene editing medicine that functionally upregulates LDLR in mice and non-human primates
Newmark Judith, Raghav Jimit, Jaskolka Michael, Diner Benjamin, Soman Vikram, Jinadasa Tushare, Apte Ameya, Wu Meng, Bottega Steve, Thakkar Mansi, Agosto Luis, Wrighton Paul, Majithia Deep, Jambard Shreya, Jansson-fritzberg Linnea, Jones Mark, Fletcher Jillian, Weiss Mckenzie, Kaye Emily, Steward Briana, Bochicchio James, Pietrasiewicz Stephen, Iovino Salvatore, Marco Rubio Eugenio, Trong Phan Huu, Chander Nisha, Kazemian Mohammadreza, Lam Kieu, Reid Steve, Dinsmore Michael, Teslovich Tanya, Xie Jenny, Gupta Anshul, Amin Parth, Burkly Linda, Thompson Morgan, Rizal Salu, Bilodeau Maxime, Dong Ruhong, Zhen Wei
Final Pr. ID: MP1123
Authors: Newmark Judith , Raghav Jimit , Jaskolka Michael , Diner Benjamin , Soman Vikram , Jinadasa Tushare , Apte Ameya , Wu Meng , Bottega Steve , Thakkar Mansi , Agosto Luis , Wrighton Paul , Majithia Deep , Jambard Shreya , Jansson-fritzberg Linnea , Jones Mark , Fletcher Jillian , Weiss Mckenzie , Kaye Emily , Steward Briana , Bochicchio James , Pietrasiewicz Stephen , Iovino Salvatore , Marco Rubio Eugenio , Trong Phan Huu , Chander Nisha , Kazemian Mohammadreza , Lam Kieu , Reid Steve , Dinsmore Michael , Teslovich Tanya , Xie Jenny , Gupta Anshul , Amin Parth , Burkly Linda , Thompson Morgan , Rizal Salu , Bilodeau Maxime , Dong Ruhong , Zhen Wei
Keywords: Atherosclerosis, Cardiovascular disease, Cholesterol-lowering drugs, Gene therapy, Hypercholesterolemia
11 : 30 AM
Adherence to Lipid Lowering Therapy among US Veterans with Atherosclerotic Cardiovascular Disease
Ward Rachel, Gaziano Michael, Wellman Helen, Yel Nedim, Young Melissa, Coleman-lopez Mason, Niu Xiaoli, Mcelligott Sean, Gagnon David, Djousse Luc
Final Pr. ID: MDP1066
Authors: Ward Rachel , Gaziano Michael , Wellman Helen , Yel Nedim , Young Melissa , Coleman-lopez Mason , Niu Xiaoli , Mcelligott Sean , Gagnon David , Djousse Luc
Keywords: Adherence, Cardiovascular disease, Cholesterol-lowering drugs, Statins
03 : 15 PM
ANGPTL3 Targeting Monoclonal Antibodies Lead to Robust Reductions in LDL-C, Triglycerides, ApoB, and Non-HDL-C in Dyslipidemic Patients: A Meta-Analysis of 5 Randomized Controlled Trials
Daid Simranpreet Singh, Sharma Anubhuti, Sharma Arundhati, Pannu Sagal, Asnani Heena, Bhanushali Karan, Choudhary Khushal, Sharma Saurabh
Final Pr. ID: Su2130
Authors: Daid Simranpreet Singh , Sharma Anubhuti , Sharma Arundhati , Pannu Sagal , Asnani Heena , Bhanushali Karan , Choudhary Khushal , Sharma Saurabh
Keywords: LDL, Cholesterol-lowering drugs, Dyslipidemia, Monoclonal antibodies, Hypercholesterolemia
10 : 30 AM
Assessing the Efficacy and Safety of Olezarsen in Lowering Triglyceride Levels: A Systematic Review and Meta-Analysis
Shahzad Zoha, Batool Asma, Ijaz Osama, Rao Asad Gul, Rasool Warda, Wani Shariq Ahmad, Rauf Faateh, Ilmaguook Badr, Khan Arslan Ahmed, Bhatti Ali Hanif
Final Pr. ID: Sa1026
Authors: Shahzad Zoha , Batool Asma , Ijaz Osama , Rao Asad Gul , Rasool Warda , Wani Shariq Ahmad , Rauf Faateh , Ilmaguook Badr , Khan Arslan Ahmed , Bhatti Ali Hanif
Keywords: Triglycerides, Apolipoproteins, Cholesterol, Cholesterol-lowering drugs, Cardiovascular disease
10 : 45 AM
Bempedoic acid monotherapy, LDL cholesterol and cardiovascular events: a secondary analysis of the CLEAR Outcomes trial
Zingano Carolina, Brennan Danielle, Li Na, Herout Peter, Powell Heather, Bloedon Leanne, Nissen Steven, Laffin Luke
Final Pr. ID: 4361027
Authors: Zingano Carolina , Brennan Danielle , Li Na , Herout Peter , Powell Heather , Bloedon Leanne , Nissen Steven , Laffin Luke
Keywords: Cardiovascular disease prevention, Cholesterol-lowering drugs, LDL, Cardiovascular disease, Prevention
01 : 52 PM
Cardiologist Attitude to Lipid Control in Patients with ASCVD without Major Cardiovascular Events: Insights from the 2024 ACS EuroPath Survey
Zaman Azfar, De Caterina Raffaele, Schiele Francois, Sionis Alessandro, Catapano Alberico, Laufs Ulrich
Final Pr. ID: MP2081
Authors: Zaman Azfar , De Caterina Raffaele , Schiele Francois , Sionis Alessandro , Catapano Alberico , Laufs Ulrich
Keywords: Acute coronary syndromes, Cardiovascular Risk, Cholesterol-lowering drugs, Guidelines
03 : 15 PM
Cardiology Follow-Up as a Determinant of LDL-C Management Success in Secondary Cardiovascular Prevention
Sedrakyan Surik, Laband William, Nadeem Bilawal, Lam Uyen
Final Pr. ID: Su3152
Authors: Sedrakyan Surik , Laband William , Nadeem Bilawal , Lam Uyen
Keywords: Coronary artery disease, Lipids, Cholesterol-lowering drugs
09 : 29 AM
Cholesterol Management in US Individuals with ASCVD within the Family Heart Database® during 2022/23: Current State of Care and Opportunities for Improvement
Macdougall Diane, Ferdinand Keith, Baum Seth, Sperling Laurence, Hartsuff Bonnie, Wilemon Katherine, Nissen Steven
Final Pr. ID: MP1485
Authors: Macdougall Diane , Ferdinand Keith , Baum Seth , Sperling Laurence , Hartsuff Bonnie , Wilemon Katherine , Nissen Steven
Keywords: Cholesterol-lowering drugs, Cardiovascular disease, Patient centered care, Big Data
07 : 00 PM
Comparison of Lipid-Lowering Therapies Regimens and LDL-C Profiles in Patients with Asymptomatic versus Acute Symptomatic Atherosclerotic Carotid Stenosis
Vlachos Dimitrios, Katan Mira, De Bresser Carolijn, De Borst Gert Jan, Wegener Susanne, De Marchis Gian Marco, Dittrich Tolga, Toebak Anna Marijn, Pereppadan Sruthy, Frenger Johannes, Jeker Benjamin, Farah Ioannis, Bruelisauer Shania, Inauen Corinne
Final Pr. ID: TP318
Authors: Vlachos Dimitrios , Katan Mira , De Bresser Carolijn , De Borst Gert Jan , Wegener Susanne , De Marchis Gian Marco , Dittrich Tolga , Toebak Anna Marijn , Pereppadan Sruthy , Frenger Johannes , Jeker Benjamin , Farah Ioannis , Bruelisauer Shania , Inauen Corinne
Keywords: Carotid stenosis, Stroke, Prevention, Cholesterol-lowering drugs, Atherosclerosis
Shustak Rachel, Perlstein Abigail, Artis Amanda, Zavez Alexis, Tam Vicky, Martino Giordana, Brothers Julie
Final Pr. ID: MDP182
Authors: Shustak Rachel , Perlstein Abigail , Artis Amanda , Zavez Alexis , Tam Vicky , Martino Giordana , Brothers Julie
Keywords: Cholesterol, Cholesterol-lowering drugs, Cholesterol screening, Social determinants, Socioeconomic position