Showing 11 Abstracts.
04 : 30 PM
Adeno-associated virus-mediated gene delivery of PERM1 enhances cardiac contractility and mitochondrial biogenesis in mice.
Sreedevi Karthi, Doku Abigail Oforiwaa, James Amina, Do Sara, Zaitsev Alexey, Warren Junco
Final Pr. ID: Tu093
Authors: Sreedevi Karthi , Doku Abigail Oforiwaa , James Amina , Do Sara , Zaitsev Alexey , Warren Junco
Keywords: Heart failure, Cardiac metabolism, Mitochondria, Contractility, Gene therapy
04 : 30 PM
Cardioactive molecules identified by functional in vivo screening prevent anthracycline cardiotoxicity
Bortolotti Francesca, Mura Antonio, Riccio Matteo Maria, Dal Ferro Matteo, Zentilin Lorena, Giacca Mauro
Final Pr. ID: Mo014
Authors: Bortolotti Francesca , Mura Antonio , Riccio Matteo Maria , Dal Ferro Matteo , Zentilin Lorena , Giacca Mauro
Keywords: Cardio-oncology, Apoptosis, Autophagy, Gene therapy, Cardiomyopathy
04 : 30 PM
cBIN1 Gene Therapy Improves Left Ventricular Filling Pressure in a Canine Model of Ischemic Dilated Cardiomyopathy
Khan Muhammad, Shaw Robin, Dosdall Derek, Yazaki Kyoichiro, Ishidoya Yuki, Offei Emmanuel, Ruizcastillo Sofia, Shah Ankur, Li Jing, Palatinus Joseph, Hong Tingting
Final Pr. ID: We105
Authors: Khan Muhammad , Shaw Robin , Dosdall Derek , Yazaki Kyoichiro , Ishidoya Yuki , Offei Emmanuel , Ruizcastillo Sofia , Shah Ankur , Li Jing , Palatinus Joseph , Hong Tingting
Keywords: Gene therapy, Ischemic heart disease, Ventricular remodeling, Myocardial infarction, Pressure volume relation
04 : 30 PM
Efficient Intramyocardial Delivery of EV-Encapsulated AAVs to Target Cardiomyocytes in a Pre-Clinical Swine Model
Gallinat Alex, Sahoo Susmita, La Salvia Sabrina, Li Xisheng, Raisinghani Nikhil, Zhang Shihong, Shao Alan, Phan Anh, Mavropoulos Spyros, Ishikawa Kiyotake
Final Pr. ID: Tu008
Authors: Gallinat Alex , Sahoo Susmita , La Salvia Sabrina , Li Xisheng , Raisinghani Nikhil , Zhang Shihong , Shao Alan , Phan Anh , Mavropoulos Spyros , Ishikawa Kiyotake
Keywords: Gene therapy, Gene transfer, Myocardium
04 : 30 PM
Gene therapy of MAOA fine-tunes nuclear cAMP nanodomain and improves cardiac hypertrophy in mice
Xiang Wenjing, Sun Xingsheng, Su Chunyu, Xiang Yang, Wang Ying
Final Pr. ID: We096
Authors: Xiang Wenjing , Sun Xingsheng , Su Chunyu , Xiang Yang , Wang Ying
Keywords: Cardiac hypertrophy, Gene therapy, Targeted therapeutics
04 : 30 PM
Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes as an In Vitro Model to Evaluate the Efficacy of a Gene Replacement Therapy for Plakophilin-2-Associated Arrhythmogenic Right Ventricular Cardiomyopathy
Perea Gil Isaac, Jones Chayse, Yang Zhihong Jane, Hoey Timothy, Argast Gretchen, Aycinena J. Alex, Chandrakumar Rishikesan, Cisne-thompson Olga, Tsui Jonathan, Zepeda Bernardo, Tefera Anley, Shenwai Reva, Farshidfar Farshad
Final Pr. ID: Mo092
Authors: Perea Gil Isaac , Jones Chayse , Yang Zhihong Jane , Hoey Timothy , Argast Gretchen , Aycinena J. Alex , Chandrakumar Rishikesan , Cisne-thompson Olga , Tsui Jonathan , Zepeda Bernardo , Tefera Anley , Shenwai Reva , Farshidfar Farshad
Keywords: Gene therapy, Stem cells, Cardiomyopathy, Tissue engineering
04 : 30 PM
Modified mRNA Therapeutics Inhibits Cardiomyocyte Apoptosis and Induces Cardiac Protection in Ischemic Heart Diseases
Magadum Ajit, Kishore Raj, Mallaredy Vandana, Roy Rajika, Gurrala Charan Thej, Joladarashi Darukeshwara, Cimini Maria, Gonzalez Carolina, Truongcao May, Benedict Cindy
Final Pr. ID: We115
Authors: Magadum Ajit , Kishore Raj , Mallaredy Vandana , Roy Rajika , Gurrala Charan Thej , Joladarashi Darukeshwara , Cimini Maria , Gonzalez Carolina , Truongcao May , Benedict Cindy
Keywords: Cardiovascular therapeutics, Cardiovascular disease, Cardiac regeneration, Apoptosis, Gene therapy
04 : 30 PM
Preclinical Evidence of Long-term Efficacy and Safety of LX2020, an AAV based Plakophilin-2 Gene Therapy, for the Treatment of Arrhythmogenic Cardiomyopathy
Zhang Jing, Sheikh Farah, Gutierrez Lara Erika, Do Aryanne, Nguyen Lena, Nair Anju, Selvan Nithya, Fenn Tim, Adler Eric, Khanna Richie
Final Pr. ID: We117
Authors: Zhang Jing , Sheikh Farah , Gutierrez Lara Erika , Do Aryanne , Nguyen Lena , Nair Anju , Selvan Nithya , Fenn Tim , Adler Eric , Khanna Richie
Keywords: Cardiomyopathy, Ventricular function, Gene therapy, Ventricular remodeling, Ventricular arrhythmia
Liu Ning, Jianqiu Pei, Xie Yifan, Nie Yu
Final Pr. ID: We035
Authors: Liu Ning , Jianqiu Pei , Xie Yifan , Nie Yu
Keywords: Cardiac regeneration, Cardioprotection, Myocardial infarction, Gene therapy, Ischemic heart disease
Miguel Dos Santos Rodrigo, Mesquita Thassio, Sanchez Lizbeth, Li Liang, Marban Eduardo, Cingolani Eugenio
Final Pr. ID: Mo072
Authors: Miguel Dos Santos Rodrigo , Mesquita Thassio , Sanchez Lizbeth , Li Liang , Marban Eduardo , Cingolani Eugenio
Keywords: Pacemakers, Gene therapy, Sinoatrial node
09 : 00 AM
Transcription Factor Gene Therapy for Treatment of Junctional Bradycardia in a Porcine Model of Complete Atrioventricular Block Following His Bundle Ablation
Ramirez Rafael, Fan Jinqi, Cho Hee Cheol, Bergman Samuel, Masri Jamal, Weltz Alexander, Kumar Naman, De La Uz Caridad, Kolandaivelu Aravindan, Barth Andreas, Barcelon Bernadette
Final Pr. ID: Or118
Authors: Ramirez Rafael , Fan Jinqi , Cho Hee Cheol , Bergman Samuel , Masri Jamal , Weltz Alexander , Kumar Naman , De La Uz Caridad , Kolandaivelu Aravindan , Barth Andreas , Barcelon Bernadette
Keywords: Gene therapy, Heart block, Arrhythmias, treatment of, Pacemakers, Pacing