American Heart Association
Basic Science Innovations in Vascular Medicine
Moderated Digital Poster Session
Clinical Science Zone 2, Moderated Digital Poster 21
Nov 9th , 03:15 PM - 04:15 PM
03 : 15 PM
MST1 Promotes the Development of Aortic Aneurysm and Dissection by Inhibiting FLNB-RAC1 Activity
Sang He, Ji Zhiqi, Li Jinzhang, Wang Meili, Jaing Wenjian, Zhang Hongjia
Final Pr. ID: MP1728
Authors: Sang He, Ji Zhiqi, Li Jinzhang, Wang Meili, Jaing Wenjian, Zhang Hongjia
Keywords: Aortic aneurysm , Aortic Dissection , Smooth muscle , Vasoconstriction
Shu Ting, Liu Siyang, Chen Si, Mcdowell James, Long Xiaochun, Yan Chen
Final Pr. ID: MP1729
Authors: Shu Ting, Liu Siyang, Chen Si, Mcdowell James, Long Xiaochun, Yan Chen
Keywords: Aortic aneurysm , Vascular disease , Smooth muscle
03 : 29 PM
Fibrinogen–Bmal1 Signaling as a Novel Therapeutic Target for Preserving Vascular Smooth Muscle Cell Contractility and Limiting Aortic Dissection Progression
Zhong Xiaohan, Li Dongjie, Ma Xinliang, Jiang Wenjian, Wang Meili, Zhang Hongjia
Final Pr. ID: MP1730
Authors: Zhong Xiaohan, Li Dongjie, Ma Xinliang, Jiang Wenjian, Wang Meili, Zhang Hongjia
Keywords: Aortic Dissection , Aortic aneurysm , Cardiovascular disease
03 : 36 PM
Selective Degradation of Excess Free Cholesterol in the Liver by REP-0003 Regresses Atherosclerotic Plaque in Ldlr -/- Mice: A Novel Approach for HoFH
Strough Garrett, Khan Bobby, . Reason, Topors Mourad, Warren Iyan, Sahbani Karim, Inyang Kufreobong, Li Jing, Hickey Brendan, Plencner Stephen, Honkanen Richard, Bhatt Deepak
Final Pr. ID: MP1731
Authors: Strough Garrett, Khan Bobby, . Reason, Topors Mourad, Warren Iyan, Sahbani Karim, Inyang Kufreobong, Li Jing, Hickey Brendan, Plencner Stephen, Honkanen Richard, Bhatt Deepak
Keywords: Atherosclerosis , Hypercholesterolemia , Cardiovascular disease , Plaque , Gene therapy
03 : 43 PM
Recovery of Aortic Wall Structure in Mouse Models of Marfan Syndrome with Conditional Inactivation of ADAMTS6
Mital Rahul, Seifert Deborah, Alcocer Ana, Lin Connie, Rush Elizabeth, Mead Timothy
Final Pr. ID: MP1733
Authors: Mital Rahul, Seifert Deborah, Alcocer Ana, Lin Connie, Rush Elizabeth, Mead Timothy
Keywords: Marfan's Syndrome , Aortic aneurysm , Aortopathies , Electrocardiography , Cardiovascular disease
03 : 50 PM
The Impact of an Investigational First-In-Class Fully Human Natriuretic Peptide Receptor 1-Blocking Monoclonal Antibody REGN7544 on Systolic Blood Pressure and Hypovolemic and Hypotensive Disorders in Mice
Devalaraja-narashimha Kishor, Hernandez Annabel Romero, Ho Andre Jo-hao, Itani Hana, Kumar Mohit, Garnova Elena, Rafique Ashique, Krueger Pamela, Pan Hao, Wang Mao, Huang Tammy, Dunn Michael, Marin Ethan, Murphy Andrew, Yancopoulos George, Olenchock Benjamin, Olson William, Morton Lori, Jin Ximei, Zhang Dongqin, Torello Justin, Mao Xia, Shekhar Akshay, Kim Jee, Franklin Matthew
Final Pr. ID: MP1734
Authors: Devalaraja-narashimha Kishor, Hernandez Annabel Romero, Ho Andre Jo-hao, Itani Hana, Kumar Mohit, Garnova Elena, Rafique Ashique, Krueger Pamela, Pan Hao, Wang Mao, Huang Tammy, Dunn Michael, Marin Ethan, Murphy Andrew, Yancopoulos George, Olenchock Benjamin, Olson William, Morton Lori, Jin Ximei, Zhang Dongqin, Torello Justin, Mao Xia, Shekhar Akshay, Kim Jee, Franklin Matthew
Keywords: Natriuretic peptide , Monoclonal antibodies , Blood pressure
03 : 57 PM
Promoting the Thrombosis-Induced Alox15 Pathway for the Treatment of Inflammatory Lung Injury
Evans Colin, Zhang Xianming, Machireddy Narsa, Phillips Mollie, Dhar Rana, Chakrabarti Mrinmay, David Odile, Zhao Youyang
Final Pr. ID: MP1735
Authors: Evans Colin, Zhang Xianming, Machireddy Narsa, Phillips Mollie, Dhar Rana, Chakrabarti Mrinmay, David Odile, Zhao Youyang
Keywords: Endothelium , Pulmonary vascular biology , Thrombosis , Inflammation , Lipids
04 : 04 PM
Rab9-dependent Mitophagy is a Comprehensive Therapeutic Target for Cardiovascular Senescence, Atherosclerosis and Sarcopenia in Postmenopausal Women
Uebo Shota, Ikeda Yoshiyuki, Sasaki Yuichi, Uchikado Yoshihiro, Akasaki Yuichi, Kubozono Takuro, Ohishi Mitsuru
Final Pr. ID: MP1737
Authors: Uebo Shota, Ikeda Yoshiyuki, Sasaki Yuichi, Uchikado Yoshihiro, Akasaki Yuichi, Kubozono Takuro, Ohishi Mitsuru
Keywords: Autophagy , Mitochondria , Aging , Atherosclerosis , Cardiovascular health
03 : 29 PM
Fibrinogen–Bmal1 Signaling as a Novel Therapeutic Target for Preserving Vascular Smooth Muscle Cell Contractility and Limiting Aortic Dissection Progression
Zhong Xiaohan, Li Dongjie, Ma Xinliang, Jiang Wenjian, Wang Meili, Zhang Hongjia
Final Pr. ID: MP1730
Authors: Zhong Xiaohan, Li Dongjie, Ma Xinliang, Jiang Wenjian, Wang Meili, Zhang Hongjia
Keywords: Aortic Dissection , Aortic aneurysm , Cardiovascular disease
03 : 15 PM
MST1 Promotes the Development of Aortic Aneurysm and Dissection by Inhibiting FLNB-RAC1 Activity
Sang He, Ji Zhiqi, Li Jinzhang, Wang Meili, Jaing Wenjian, Zhang Hongjia
Final Pr. ID: MP1728
Authors: Sang He, Ji Zhiqi, Li Jinzhang, Wang Meili, Jaing Wenjian, Zhang Hongjia
Keywords: Aortic aneurysm , Aortic Dissection , Smooth muscle , Vasoconstriction
03 : 57 PM
Promoting the Thrombosis-Induced Alox15 Pathway for the Treatment of Inflammatory Lung Injury
Evans Colin, Zhang Xianming, Machireddy Narsa, Phillips Mollie, Dhar Rana, Chakrabarti Mrinmay, David Odile, Zhao Youyang
Final Pr. ID: MP1735
Authors: Evans Colin, Zhang Xianming, Machireddy Narsa, Phillips Mollie, Dhar Rana, Chakrabarti Mrinmay, David Odile, Zhao Youyang
Keywords: Endothelium , Pulmonary vascular biology , Thrombosis , Inflammation , Lipids
04 : 04 PM
Rab9-dependent Mitophagy is a Comprehensive Therapeutic Target for Cardiovascular Senescence, Atherosclerosis and Sarcopenia in Postmenopausal Women
Uebo Shota, Ikeda Yoshiyuki, Sasaki Yuichi, Uchikado Yoshihiro, Akasaki Yuichi, Kubozono Takuro, Ohishi Mitsuru
Final Pr. ID: MP1737
Authors: Uebo Shota, Ikeda Yoshiyuki, Sasaki Yuichi, Uchikado Yoshihiro, Akasaki Yuichi, Kubozono Takuro, Ohishi Mitsuru
Keywords: Autophagy , Mitochondria , Aging , Atherosclerosis , Cardiovascular health
03 : 43 PM
Recovery of Aortic Wall Structure in Mouse Models of Marfan Syndrome with Conditional Inactivation of ADAMTS6
Mital Rahul, Seifert Deborah, Alcocer Ana, Lin Connie, Rush Elizabeth, Mead Timothy
Final Pr. ID: MP1733
Authors: Mital Rahul, Seifert Deborah, Alcocer Ana, Lin Connie, Rush Elizabeth, Mead Timothy
Keywords: Marfan's Syndrome , Aortic aneurysm , Aortopathies , Electrocardiography , Cardiovascular disease
03 : 36 PM
Selective Degradation of Excess Free Cholesterol in the Liver by REP-0003 Regresses Atherosclerotic Plaque in Ldlr -/- Mice: A Novel Approach for HoFH
Strough Garrett, Khan Bobby, . Reason, Topors Mourad, Warren Iyan, Sahbani Karim, Inyang Kufreobong, Li Jing, Hickey Brendan, Plencner Stephen, Honkanen Richard, Bhatt Deepak
Final Pr. ID: MP1731
Authors: Strough Garrett, Khan Bobby, . Reason, Topors Mourad, Warren Iyan, Sahbani Karim, Inyang Kufreobong, Li Jing, Hickey Brendan, Plencner Stephen, Honkanen Richard, Bhatt Deepak
Keywords: Atherosclerosis , Hypercholesterolemia , Cardiovascular disease , Plaque , Gene therapy
03 : 50 PM
The Impact of an Investigational First-In-Class Fully Human Natriuretic Peptide Receptor 1-Blocking Monoclonal Antibody REGN7544 on Systolic Blood Pressure and Hypovolemic and Hypotensive Disorders in Mice
Devalaraja-narashimha Kishor, Hernandez Annabel Romero, Ho Andre Jo-hao, Itani Hana, Kumar Mohit, Garnova Elena, Rafique Ashique, Krueger Pamela, Pan Hao, Wang Mao, Huang Tammy, Dunn Michael, Marin Ethan, Murphy Andrew, Yancopoulos George, Olenchock Benjamin, Olson William, Morton Lori, Jin Ximei, Zhang Dongqin, Torello Justin, Mao Xia, Shekhar Akshay, Kim Jee, Franklin Matthew
Final Pr. ID: MP1734
Authors: Devalaraja-narashimha Kishor, Hernandez Annabel Romero, Ho Andre Jo-hao, Itani Hana, Kumar Mohit, Garnova Elena, Rafique Ashique, Krueger Pamela, Pan Hao, Wang Mao, Huang Tammy, Dunn Michael, Marin Ethan, Murphy Andrew, Yancopoulos George, Olenchock Benjamin, Olson William, Morton Lori, Jin Ximei, Zhang Dongqin, Torello Justin, Mao Xia, Shekhar Akshay, Kim Jee, Franklin Matthew
Keywords: Natriuretic peptide , Monoclonal antibodies , Blood pressure
Shu Ting, Liu Siyang, Chen Si, Mcdowell James, Long Xiaochun, Yan Chen
Final Pr. ID: MP1729
Authors: Shu Ting, Liu Siyang, Chen Si, Mcdowell James, Long Xiaochun, Yan Chen
Keywords: Aortic aneurysm , Vascular disease , Smooth muscle