Showing Results from 1 to 12 of 191.
04 : 30 PM
3-Mercaptopyruvate Sulfurtransferase is a Critical Regulator of Branched-Chain Amino Acid Catabolism in Cardiometabolic HFpEF
Li Zhen, Doiron Jake, Xia Huijing, Lapenna Kyle, Sharp Thomas, Yu Xiaoman, Nagahara Noriyuki, Goodchild Traci, Lefer David
Final Pr. ID: Mo101
Authors: Li Zhen , Doiron Jake , Xia Huijing , Lapenna Kyle , Sharp Thomas , Yu Xiaoman , Nagahara Noriyuki , Goodchild Traci , Lefer David
Keywords: HFpEF, Cardiac metabolism, Mitochondria
05 : 30 PM
A High Salt Diet Drives Kidney Microvascular Dysfunction Through a Plasma-Derived Factor that Increases Mitochondrial Reactive Oxygen Species
Reynolds Lance, Guan Zhengrong, Pollock David, Pollock Jennifer
Final Pr. ID: TAC298
Authors: Reynolds Lance , Guan Zhengrong , Pollock David , Pollock Jennifer
Keywords: Sodium, Vascular, Nitric oxide, Mitochondria, Reactive oxygen intermediates
02 : 30 PM
A human cardiomyocyte model of CD36 haploinsufficiency uncovers fatty acid oxidation deficits driving dilated cardiomyopathy
Al Sayed Zeina, Klattenhoff Carla, Aragam Krishna, Ellinor Patrick, Willcox Jon, Zheng Alice, Koledova Vera, Srivastava Salil, Yin Xiaofei, Chaffin Mark, Rigaud Vagner, Kovacs-bogdan Erika
Final Pr. ID: LBP21
Authors: Al Sayed Zeina , Klattenhoff Carla , Aragam Krishna , Ellinor Patrick , Willcox Jon , Zheng Alice , Koledova Vera , Srivastava Salil , Yin Xiaofei , Chaffin Mark , Rigaud Vagner , Kovacs-bogdan Erika
Keywords: Cardiomyopathy, Metabolism, Lipids, Ethnicity, Mitochondria
09 : 15 AM
Aberrant Splicing of Mitochondrial Dynamics Genes Impairs Cardiac Bioenergetics in Myotonic Dystrophy type I (DM1)
Adesanya Oluwafolajimi, Nabie Pouya, Kalsotra Auinash
Final Pr. ID: MP2768
Authors: Adesanya Oluwafolajimi , Nabie Pouya , Kalsotra Auinash
Keywords: Mitochondrial energetics, Mitochondria, Muscle, cardiac - see Myocardium, Electrophysiology, Energetics
04 : 30 PM
Abundance Of Long-Chain Acylcarnitines As a Key Regulator Of Metabolic Reprogramming During Postnatal Cardiac Maturation In Mice
Ramasamy Saminathan, Shrestha Pratikshya, Muthu Sakthijothi, Tran Zinnia, Velayutham Murugesan, Sundararajan Venkatesh
Final Pr. ID: Thu057
Authors: Ramasamy Saminathan , Shrestha Pratikshya , Muthu Sakthijothi , Tran Zinnia , Velayutham Murugesan , Sundararajan Venkatesh
Keywords: Cardiac development, Mitochondrial energetics, Metabolism, Heart development, Mitochondria
05 : 00 PM
Acetylation of Mitochondrial Cyclophilin D Increases vascular Oxidative Stress, Induces Glycolitic Switch, Promotes Endothelial Dysfunction and Hypertension
Dikalov Sergey, Sack Michael, Dikalova Anna, Fehrenbach Daniel, Mayorov Vladimir, Panov Alexander, Ao Mingfang, Lantier Louise, Amarnath Venkataraman, Lopez Marcos, Billings Frederic
Final Pr. ID: 63
Authors: Dikalov Sergey , Sack Michael , Dikalova Anna , Fehrenbach Daniel , Mayorov Vladimir , Panov Alexander , Ao Mingfang , Lantier Louise , Amarnath Venkataraman , Lopez Marcos , Billings Frederic
Keywords: Endothelial function, Hypertension, Mitochondria, Oxidative Stress, Metabolism
08 : 30 AM
Acetylation of mitochondrial LCAD and SOD2 promotes metabolic dysfunction, oxidative stress, multi-organ damage and hypertension
Dikalov Sergey, Nogueira Marina, Polosukhin Vasiliy, Gius David, Milne Ginger, Dikalova Anna
Final Pr. ID: 094
Authors: Dikalov Sergey , Nogueira Marina , Polosukhin Vasiliy , Gius David , Milne Ginger , Dikalova Anna
Keywords: Metabolism, Oxidative Stress, Mitochondria, Hypertension, Oxidized lipids
He Lihao, Young Martin E, Rowe Glenn, Prabhu Sumanth, Sethu Palaniappan, Xie Min, Chen Yunxi, Chu Yuxin, Hua Yutao, Cai Junyan, He Jin, Benavides Gloria, Darley-usmar Victor, Ballinger Scott
Final Pr. ID: Fri116
Authors: He Lihao , Young Martin E , Rowe Glenn , Prabhu Sumanth , Sethu Palaniappan , Xie Min , Chen Yunxi , Chu Yuxin , Hua Yutao , Cai Junyan , He Jin , Benavides Gloria , Darley-usmar Victor , Ballinger Scott
Keywords: Ischemia reperfusion, Mitochondria, Autophagy, Infarct size
04 : 30 PM
Adeno-associated virus-mediated gene delivery of PERM1 enhances cardiac contractility and mitochondrial biogenesis in mice.
Sreedevi Karthi, Doku Abigail Oforiwaa, James Amina, Do Sara, Zaitsev Alexey, Warren Junco
Final Pr. ID: Tu093
Authors: Sreedevi Karthi , Doku Abigail Oforiwaa , James Amina , Do Sara , Zaitsev Alexey , Warren Junco
Keywords: Heart failure, Cardiac metabolism, Mitochondria, Contractility, Gene therapy
04 : 30 PM
Age-Related Impairment of Mitochondrial Protein Turnover Exacerbates Pathogenesis of Heart Failure with Preserved Ejection Fraction in Old Mice
Kobak Kamil, Zarzycka Weronika, King Catherine, Borowik Agnieszka, Peelor Frederick, Kinter Michael, Miller Benjamin, Chiao Ying Ann
Final Pr. ID: Mo107
Authors: Kobak Kamil , Zarzycka Weronika , King Catherine , Borowik Agnieszka , Peelor Frederick , Kinter Michael , Miller Benjamin , Chiao Ying Ann
Keywords: HFpEF, Mitochondria, Proteomics, Proteasome, Autophagy
10 : 15 AM
Alfa-tubulin detyrosination causes mitochondrial dysfunction through suppression of Parkin-mediated mitophagy linking to heart failure with preserved ejection fraction
Miura Shunsuke, Nakazato Kazuhiko, Ishida Takafumi, Takeishi Yasuchika, Sekine Toranosuke, Ogawara Ryo, Ichimura Shohei, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Kobayashi Atsushi, Yamaki Takayoshi
Final Pr. ID: 4139743
Authors: Miura Shunsuke , Nakazato Kazuhiko , Ishida Takafumi , Takeishi Yasuchika , Sekine Toranosuke , Ogawara Ryo , Ichimura Shohei , Yokokawa Tetsuro , Misaka Tomofumi , Oikawa Masayoshi , Kobayashi Atsushi , Yamaki Takayoshi
Keywords: HFpEF, Cell physiology, Mitochondria
Guan Yuntian, Banks Alexander, Gerszten Robert, Benson Mark, Jonas Zachary, Wang Alissa, Tendoh Foje-geh, Manish Mahesh, Shah Radhe, Hofmann Alissa, Shen Dongxiao, Cortopassi Marissa
Final Pr. ID: MP2746
Authors: Guan Yuntian , Banks Alexander , Gerszten Robert , Benson Mark , Jonas Zachary , Wang Alissa , Tendoh Foje-geh , Manish Mahesh , Shah Radhe , Hofmann Alissa , Shen Dongxiao , Cortopassi Marissa
Keywords: Metabolism, Cardiometabolic health, Mitochondria, Energetics, Obesity