Showing 11 Abstracts.
03 : 45 PM
CD44 Knockdown Attenuates the Abnormal Cellular Phenotype of BMPR2-Deficient Primary Human Pulmonary Artery Endothelial Cells
Siddique Md Abdul Hai, Chen Li-yuan, Awad Keytam S., Wang Shuibang, Danner Robert, Elinoff Jason
Final Pr. ID: MDP823
Authors: Siddique Md Abdul Hai , Chen Li-yuan , Awad Keytam S. , Wang Shuibang , Danner Robert , Elinoff Jason
Keywords: Pulmonary vascular biology, Pulmonary hypertension, Endothelial function, Gene mutations, Hypertension: experimental
Hong Jason, Wong Brenda, Brownstein Adam, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh
Final Pr. ID: Sa4116
Authors: Hong Jason , Wong Brenda , Brownstein Adam , Graves Tammy , Aldred Micheala , Dai Zhiyu , Yang Xia , Eghbali Mansoureh
Keywords: Pulmonary hypertension, Pulmonary vascular biology, Transcriptomics
11 : 40 AM
Dual Inhibition of Glutaminolysis and Pyruvate Carboxylase Attenuates Pulmonary Arterial Hypertension
Valuparampil Varghese Mathews, James Joel, Bharti Dinesh, Niihori Maki, Rafikova Olga, Rafikov Ruslan
Final Pr. ID: MDP1113
Authors: Valuparampil Varghese Mathews , James Joel , Bharti Dinesh , Niihori Maki , Rafikova Olga , Rafikov Ruslan
Keywords: Pulmonary hypertension, Metabolism, Mitochondrial energetics, Pulmonary heart disease, Pulmonary vascular biology
10 : 00 AM
General Capillary Endothelial Cells Undergo Reprogramming into Arterial Endothelial Cells in Pulmonary Hypertension
Liu Bin, Yi Dan, Xia Xiaomei, Ramirez Karina, Zhao Hanqiu, Tripathi Ankit, Fallon Michael, Dai Zhiyu
Final Pr. ID: 4144996
Authors: Liu Bin , Yi Dan , Xia Xiaomei , Ramirez Karina , Zhao Hanqiu , Tripathi Ankit , Fallon Michael , Dai Zhiyu
Keywords: Pulmonary hypertension, Endovascular, Pulmonary vascular biology
03 : 15 PM
MHCIIhiLYVE1loCCR2hi Interstitial Macrophages Promote Medial Fibrosis in Pulmonary Arterioles and Contribute to Pulmonary Hypertension
Qiu Fan, Jiang Bo, Zhang Yi-qian, Miao Hao-ran, Hui Hong-liang, Yangui Lin, Li Hua-ming, Li Dan, Luo Min, Ong Sang-bing, Hu Xue-fei
Final Pr. ID: Su4175
Authors: Qiu Fan , Jiang Bo , Zhang Yi-qian , Miao Hao-ran , Hui Hong-liang , Yangui Lin , Li Hua-ming , Li Dan , Luo Min , Ong Sang-bing , Hu Xue-fei
Keywords: Pulmonary hypertension, Pulmonary vascular biology, Inflammation and inflammatory markers
10 : 30 AM
Non-canonical CDC20 signaling promotes smooth muscle and adventitial fibroblasts hyper-proliferation and remodeling in pulmonary arterial hypertension
Dey Tapan, Wolters Paul, Jiang Lifeng, Goncharova Elena, Goncharov Dmitry, Zhyvylo Iryna, Lin Derek, Shah Maanvi, Saiyed Aisha, Neeli Sanjana, Kudryashova Tatiana, Greenland John
Final Pr. ID: Sa4117
Authors: Dey Tapan , Wolters Paul , Jiang Lifeng , Goncharova Elena , Goncharov Dmitry , Zhyvylo Iryna , Lin Derek , Shah Maanvi , Saiyed Aisha , Neeli Sanjana , Kudryashova Tatiana , Greenland John
Keywords: Pulmonary hypertension, Pulmonary vascular biology, Pulmonary artery, Cell signaling
10 : 30 AM
RKER-012, A Novel Modified ActRIIB Ligand Trap, Reversed Experimental Pulmonary Arterial Hypertension
Jain Pritesh, Seehra Jasbir, Lerner Lorena, Joshi Sachindra Raj, Babbs Keith, Nurse Tandy, Thakre Apoorv Vinod, Pinkus Cynthia, Thirumurthy Gomathi, Ishimwe Jeanne A, Fisher Ffolliott, Lachey Jennifer
Final Pr. ID: LBP29
Authors: Jain Pritesh , Seehra Jasbir , Lerner Lorena , Joshi Sachindra Raj , Babbs Keith , Nurse Tandy , Thakre Apoorv Vinod , Pinkus Cynthia , Thirumurthy Gomathi , Ishimwe Jeanne A , Fisher Ffolliott , Lachey Jennifer
Keywords: Heart failure, Pulmonary hypertension, Echocardiography, Pulmonary vascular biology
10 : 00 AM
Single cell analysis of rat Glenn circulation identifies multiple dysregulated endothelial signaling pathways
Spearman Andrew, Rousseau Henry, Wan Tina, Wendt Andrae Jaime, Mathison Angela, Miller Amanda, Jin Victor, Pan Amy, Ramchandran Ramani
Final Pr. ID: 4143890
Authors: Spearman Andrew , Rousseau Henry , Wan Tina , Wendt Andrae Jaime , Mathison Angela , Miller Amanda , Jin Victor , Pan Amy , Ramchandran Ramani
Keywords: Single ventricle, Arteriovenous malformation (AVM), Pulmonary vascular biology, Endothelial, Molecular biology
10 : 45 AM
Single-cell and Spatial Transcriptomics Identified Fatty Acid-binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension
Liu Bin, Yi Dan, Li Shuai, Ramirez Karina, Xia Xiaomei, Cao Yanhong, Dejesus Vinicio, Glembotski Christopher, Dai Zhiyu
Final Pr. ID: 4115669
Authors: Liu Bin , Yi Dan , Li Shuai , Ramirez Karina , Xia Xiaomei , Cao Yanhong , Dejesus Vinicio , Glembotski Christopher , Dai Zhiyu
Keywords: Pulmonary hypertension, Vascular disease, Cardiovascular, Pulmonary vascular biology, Endothelium
09 : 45 AM
Single-Nucleus Transcriptome Profiling Identifies Phenotypic Shift in Pulmonary Vascular Endothelial Subpopulations in Pulmonary Arterial Hypertension
Dai Jingbo
Final Pr. ID: 4146398
Authors: Dai Jingbo
Keywords: Pulmonary hypertension, Endothelial function, Transcriptomics, Pulmonary vascular biology, Inflammation and inflammatory markers
02 : 00 PM
Tipping Point Analysis Identifies C-terminal src kinase-Collagen 22 Regulation by Inflammation in the Pathogenesis of Early-Stage Pulmonary Arterial Hypertension
Wertheim Bradley, Padera Robert, Loscalzo Joseph, Maron Brad, Wang Ruisheng, Arons Elena, Oldham William, Alba George, Bowman Frederick, Sharma Nirmal, Haley Kathleen, Samokhin Andriy
Final Pr. ID: Sa4175
Authors: Wertheim Bradley , Padera Robert , Loscalzo Joseph , Maron Brad , Wang Ruisheng , Arons Elena , Oldham William , Alba George , Bowman Frederick , Sharma Nirmal , Haley Kathleen , Samokhin Andriy
Keywords: Pulmonary hypertension, Pulmonary vascular biology, Pulmonary circulation, Endothelial function, Fibrosis