American Heart Association
Microbiome and Metabolism: Unraveling Their Role in Pulmonary Vascular Disease and Heart Failure
Moderated Digital Poster Session
Clinical Science Zone 2, Moderated Digital Poster 22
Nov 10th , 01:45 PM - 02:45 PM
01 : 45 PM
Metabolomics of Right Ventricular Systolic Function Across the Spectrum of Pulmonary Hypertension – insights from the PVDOMICS Cohort
Garry Jonah, Chung Samuel, Chacon-barahona Jonathan, Frantz Robert, Rischard Franz, Simpson Catherine, Hassoun Paul, Mathai Stephen, Krumsiek Jan, Racanelli Alexandra, Brittain Evan, Hemnes Anna, Horn Evelyn
Final Pr. ID: MP2622
Authors: Garry Jonah, Chung Samuel, Chacon-barahona Jonathan, Frantz Robert, Rischard Franz, Simpson Catherine, Hassoun Paul, Mathai Stephen, Krumsiek Jan, Racanelli Alexandra, Brittain Evan, Hemnes Anna, Horn Evelyn
Keywords: Metabolomics , Right Ventricular Dysfunction , Pulmonary hypertension
01 : 52 PM
Fatty Acid Metabolism and CPT2 Genotype May Influence Selexipag Responsiveness in Pulmonary Arterial Hypertension
Chida-nagai Ayako, Sato Hiroki, Akagawa Hiroyuki, Sato Takahiro, Tsujino Ichizo, Takeda Atsuhito
Final Pr. ID: MP2623
Authors: Chida-nagai Ayako, Sato Hiroki, Akagawa Hiroyuki, Sato Takahiro, Tsujino Ichizo, Takeda Atsuhito
Keywords: Pulmonary hypertension , Genetics , Metabolomics
01 : 59 PM
The Glucose–RBPJ–Mitochondrial Axis: A Metabolic Trigger of Pulmonary Arterial Hypertension
Valuparampil Varghese Mathews, James Joel, Bharti Dinesh, Rafikova Olga, Rafikov Ruslan
Final Pr. ID: MP2624
Authors: Valuparampil Varghese Mathews, James Joel, Bharti Dinesh, Rafikova Olga, Rafikov Ruslan
Keywords: Pulmonary hypertension , Vascular disease , Mitochondria , Cell signaling , Pulmonary vascular biology
02 : 06 PM
Specific Fungal Species Supplementation Augments Right Ventricular Function in Preclinical Pulmonary Arterial Hypertension
Kremer Benjamin, Ngo Elizabeth, Huang Cheryl, Ho Truc, Prisco Sasha
Final Pr. ID: MP2625
Authors: Kremer Benjamin, Ngo Elizabeth, Huang Cheryl, Ho Truc, Prisco Sasha
Keywords: Right Ventricular Dysfunction , Right Ventricular , Pulmonary hypertension , Microbiome
02 : 13 PM
Decreased nitrate reduction capacity of oral microbiota is associated with increased severity of pulmonary hypertension
Yang Haopu, Radder Josiah, Koch Carl, Fitch Adam, Britton Noel, Shiva Sruti, Zhang Biying, Simon Marc, Qin Shulin, Methe Barbara, Li Kelvin, Gladwin Mark, Morris Alison
Final Pr. ID: MP2626
Authors: Yang Haopu, Radder Josiah, Koch Carl, Fitch Adam, Britton Noel, Shiva Sruti, Zhang Biying, Simon Marc, Qin Shulin, Methe Barbara, Li Kelvin, Gladwin Mark, Morris Alison
Keywords: Microbiome , Nitric oxide , Nitrates , Pulmonary hypertension
02 : 20 PM
Increased Skeletal Muscle Mass Normalizes Cardiac Metabolic Pathways and Attenuates Left Ventricular Hypertrophy and Diastolic Dysfunction in Hypertrophic Cardiomyopathy
Baka Tomas, Qin Fuzhong, Zhang Aifeng, Seta Francesca, Pimentel David, Sam Flora, Luptak Ivan
Final Pr. ID: MP2627
Authors: Baka Tomas, Qin Fuzhong, Zhang Aifeng, Seta Francesca, Pimentel David, Sam Flora, Luptak Ivan
Keywords: Hypertrophic cardiomyopathy , Muscle , skeletal , Metabolism
02 : 27 PM
Exogenous Ketone Supplementation Restores Length-Dependent Activation In Human Hypertrophic Cardiomyopathy Myocardium
Taichman Rebecca, Smolyak Julia, Bedi Kenneth, Patel Sapna, Cada Shawnaleh, Margulies Kenneth, Day Sharlene, Lee Benjamin
Final Pr. ID: MP2628
Authors: Taichman Rebecca, Smolyak Julia, Bedi Kenneth, Patel Sapna, Cada Shawnaleh, Margulies Kenneth, Day Sharlene, Lee Benjamin
Keywords: Hypertrophic cardiomyopathy , Contractility , Pressure – volume relation , Myocardium , Cardiac metabolism
02 : 34 PM
From Gut to Lung: Lipoxygenase Dependent Oxylipin Amplification Drives 15-HETE Induced Pulmonary Hypertension in C57BL6/J Mice
Oconnor Ellen, Emamimeybodi Maryam, Medzikovic Lejla, Hatamnejad Mohammad Reza, Dehghanitafti Ateyeh, Li Min, Ruffenach Gregoire, Mukherjee Pallavi, Eghbali Mansoureh, Reddy Srinivasa
Final Pr. ID: MP2630
Authors: Oconnor Ellen, Emamimeybodi Maryam, Medzikovic Lejla, Hatamnejad Mohammad Reza, Dehghanitafti Ateyeh, Li Min, Ruffenach Gregoire, Mukherjee Pallavi, Eghbali Mansoureh, Reddy Srinivasa
Keywords: Cardio-Thoracic , Dietary patterns , Dyslipidemia , Endothelial , Cardiovascular health
02 : 13 PM
Decreased nitrate reduction capacity of oral microbiota is associated with increased severity of pulmonary hypertension
Yang Haopu, Radder Josiah, Koch Carl, Fitch Adam, Britton Noel, Shiva Sruti, Zhang Biying, Simon Marc, Qin Shulin, Methe Barbara, Li Kelvin, Gladwin Mark, Morris Alison
Final Pr. ID: MP2626
Authors: Yang Haopu, Radder Josiah, Koch Carl, Fitch Adam, Britton Noel, Shiva Sruti, Zhang Biying, Simon Marc, Qin Shulin, Methe Barbara, Li Kelvin, Gladwin Mark, Morris Alison
Keywords: Microbiome , Nitric oxide , Nitrates , Pulmonary hypertension
02 : 27 PM
Exogenous Ketone Supplementation Restores Length-Dependent Activation In Human Hypertrophic Cardiomyopathy Myocardium
Taichman Rebecca, Smolyak Julia, Bedi Kenneth, Patel Sapna, Cada Shawnaleh, Margulies Kenneth, Day Sharlene, Lee Benjamin
Final Pr. ID: MP2628
Authors: Taichman Rebecca, Smolyak Julia, Bedi Kenneth, Patel Sapna, Cada Shawnaleh, Margulies Kenneth, Day Sharlene, Lee Benjamin
Keywords: Hypertrophic cardiomyopathy , Contractility , Pressure – volume relation , Myocardium , Cardiac metabolism
01 : 52 PM
Fatty Acid Metabolism and CPT2 Genotype May Influence Selexipag Responsiveness in Pulmonary Arterial Hypertension
Chida-nagai Ayako, Sato Hiroki, Akagawa Hiroyuki, Sato Takahiro, Tsujino Ichizo, Takeda Atsuhito
Final Pr. ID: MP2623
Authors: Chida-nagai Ayako, Sato Hiroki, Akagawa Hiroyuki, Sato Takahiro, Tsujino Ichizo, Takeda Atsuhito
Keywords: Pulmonary hypertension , Genetics , Metabolomics
02 : 34 PM
From Gut to Lung: Lipoxygenase Dependent Oxylipin Amplification Drives 15-HETE Induced Pulmonary Hypertension in C57BL6/J Mice
Oconnor Ellen, Emamimeybodi Maryam, Medzikovic Lejla, Hatamnejad Mohammad Reza, Dehghanitafti Ateyeh, Li Min, Ruffenach Gregoire, Mukherjee Pallavi, Eghbali Mansoureh, Reddy Srinivasa
Final Pr. ID: MP2630
Authors: Oconnor Ellen, Emamimeybodi Maryam, Medzikovic Lejla, Hatamnejad Mohammad Reza, Dehghanitafti Ateyeh, Li Min, Ruffenach Gregoire, Mukherjee Pallavi, Eghbali Mansoureh, Reddy Srinivasa
Keywords: Cardio-Thoracic , Dietary patterns , Dyslipidemia , Endothelial , Cardiovascular health
02 : 20 PM
Increased Skeletal Muscle Mass Normalizes Cardiac Metabolic Pathways and Attenuates Left Ventricular Hypertrophy and Diastolic Dysfunction in Hypertrophic Cardiomyopathy
Baka Tomas, Qin Fuzhong, Zhang Aifeng, Seta Francesca, Pimentel David, Sam Flora, Luptak Ivan
Final Pr. ID: MP2627
Authors: Baka Tomas, Qin Fuzhong, Zhang Aifeng, Seta Francesca, Pimentel David, Sam Flora, Luptak Ivan
Keywords: Hypertrophic cardiomyopathy , Muscle , skeletal , Metabolism
01 : 45 PM
Metabolomics of Right Ventricular Systolic Function Across the Spectrum of Pulmonary Hypertension – insights from the PVDOMICS Cohort
Garry Jonah, Chung Samuel, Chacon-barahona Jonathan, Frantz Robert, Rischard Franz, Simpson Catherine, Hassoun Paul, Mathai Stephen, Krumsiek Jan, Racanelli Alexandra, Brittain Evan, Hemnes Anna, Horn Evelyn
Final Pr. ID: MP2622
Authors: Garry Jonah, Chung Samuel, Chacon-barahona Jonathan, Frantz Robert, Rischard Franz, Simpson Catherine, Hassoun Paul, Mathai Stephen, Krumsiek Jan, Racanelli Alexandra, Brittain Evan, Hemnes Anna, Horn Evelyn
Keywords: Metabolomics , Right Ventricular Dysfunction , Pulmonary hypertension
02 : 06 PM
Specific Fungal Species Supplementation Augments Right Ventricular Function in Preclinical Pulmonary Arterial Hypertension
Kremer Benjamin, Ngo Elizabeth, Huang Cheryl, Ho Truc, Prisco Sasha
Final Pr. ID: MP2625
Authors: Kremer Benjamin, Ngo Elizabeth, Huang Cheryl, Ho Truc, Prisco Sasha
Keywords: Right Ventricular Dysfunction , Right Ventricular , Pulmonary hypertension , Microbiome
01 : 59 PM
The Glucose–RBPJ–Mitochondrial Axis: A Metabolic Trigger of Pulmonary Arterial Hypertension
Valuparampil Varghese Mathews, James Joel, Bharti Dinesh, Rafikova Olga, Rafikov Ruslan
Final Pr. ID: MP2624
Authors: Valuparampil Varghese Mathews, James Joel, Bharti Dinesh, Rafikova Olga, Rafikov Ruslan
Keywords: Pulmonary hypertension , Vascular disease , Mitochondria , Cell signaling , Pulmonary vascular biology