Showing 10 Abstracts.
Strom Joshua, Farman Gerrie, Gohlke Jochen, Van Der Pijl Robbert, Granzier Hendrikus (henk), Methawasin Mei
Final Pr. ID: Mo113
Authors: Strom Joshua , Farman Gerrie , Gohlke Jochen , Van Der Pijl Robbert , Granzier Hendrikus (henk) , Methawasin Mei
Keywords: Heart failure, adult, Muscle, cardiac - see Myocardium, Myofilaments, Women
04 : 30 PM
Computational Modeling to Predict Mechanisms of DYRK1A-mediated Inhibition of Cardiomyocyte Proliferation
Murillo Bryce, Zhao Catherine, Wu Michelle, Harris Bryana, Wintruba Kaitlyn, Saucerman Jeffrey, Wolf Matthew
Final Pr. ID: Tu071
Authors: Murillo Bryce , Zhao Catherine , Wu Michelle , Harris Bryana , Wintruba Kaitlyn , Saucerman Jeffrey , Wolf Matthew
Keywords: Cardiac regeneration, Muscle, cardiac - see Myocardium
04 : 30 PM
Efficient Intramyocardial Delivery of EV-Encapsulated AAVs to Target Cardiomyocytes in a Pre-Clinical Swine Model
Gallinat Alex, Sahoo Susmita, La Salvia Sabrina, Li Xisheng, Raisinghani Nikhil, Zhang Shihong, Shao Alan, Phan Anh, Mavropoulos Spyros, Ishikawa Kiyotake
Final Pr. ID: Tu008
Authors: Gallinat Alex , Sahoo Susmita , La Salvia Sabrina , Li Xisheng , Raisinghani Nikhil , Zhang Shihong , Shao Alan , Phan Anh , Mavropoulos Spyros , Ishikawa Kiyotake
Keywords: Gene therapy, Gene transfer, Myocardium
04 : 30 PM
Genetic Blockade of PKA-mediated Phosphoregulation of 26S Proteasomes Exacerbates Pathology in Both the Brain and Heart of an Alzheimer’s Disease Model
Ejaz Saima, Sternburg Jack, Wang Hongmin, Khosrow Rezvani, Wang Xuejun
Final Pr. ID: We132
Authors: Ejaz Saima , Sternburg Jack , Wang Hongmin , Khosrow Rezvani , Wang Xuejun
Keywords: Cognitive function, Fibrosis, Myocardium, Proteasome, Ubiquitin
04 : 30 PM
Gut Microbial Metabolite Phenylacetylglutamine Leads to Cardiomyocyte Hypercontractility and Vascular Endothelial Cell Activation
Li Zhen, Lefer David, Quijada Pearl, Makarewich Cat, Sharp Thomas, Zaparte Aline, Fu Xiaoming, Li Xinmin, Wong David, Gibson Aaron, Gorse Kiersten, Wong Zeneng, Hazen Stanley
Final Pr. ID: Tu043
Authors: Li Zhen , Lefer David , Quijada Pearl , Makarewich Cat , Sharp Thomas , Zaparte Aline , Fu Xiaoming , Li Xinmin , Wong David , Gibson Aaron , Gorse Kiersten , Wong Zeneng , Hazen Stanley
Keywords: Cardiovascular disease, Microbiome, Endothelial function, Myocardium, Diet
04 : 30 PM
Heart-Specific Histone Methyltransferase SMYD1 Promotes Cardiac Maturation in the Direct Conversion of Human Fibroblasts into Cardiomyocytes.
Woldemariam Anteneh Getachew, Li Hui, Wang Meimei, Peng William, Bridges Justin, Lu Rui, Zhou Yang
Final Pr. ID: We033
Authors: Woldemariam Anteneh Getachew , Li Hui , Wang Meimei , Peng William , Bridges Justin , Lu Rui , Zhou Yang
Keywords: Cardiac regeneration, Sarcomere, Muscle, cardiac - see Myocardium, Epigenetics, Heart failure
He Mengying, Gao Chen, Zhu Cansheng, Onubogu Nkechi, Keezer Caitlin, He Xingyu, Wang Yigang, Hu Xinyang, Sheng Shuyuan, Wang Yibin
Final Pr. ID: We130
Authors: He Mengying , Gao Chen , Zhu Cansheng , Onubogu Nkechi , Keezer Caitlin , He Xingyu , Wang Yigang , Hu Xinyang , Sheng Shuyuan , Wang Yibin
Keywords: Myocardial infarction, Heart failure, Hypoxia, Transcriptomics, Muscle, cardiac - see Myocardium
04 : 30 PM
P53 Activation Promotes Maturational Characteristics of Pluripotent Stem Cell-derived Cardiomyocytes in 3D Suspension Culture via FOXO-FOXM1 Regulation
Velayutham Nivedhitha, Shaw Jeanna, Bouffard Aldric, Morgan Sokol, Mancheno Juncosa Estela, Rhoades Seth, Van Den Berg Daphne, Kreymerman Alexander, Aoyama Junya, Hoefflin Jens, Ryan Herb, Garbern Jessica, Ho Sui Shannan, Lee Richard, Elwell Hannah, Zhuo Zhu, Ruland Laura, Elcure Alvarez Farid, Frontini Sara, Rodriguez Carreras Yago, Ricci-blair Elisabeth
Final Pr. ID: We023
Authors: Velayutham Nivedhitha , Shaw Jeanna , Bouffard Aldric , Morgan Sokol , Mancheno Juncosa Estela , Rhoades Seth , Van Den Berg Daphne , Kreymerman Alexander , Aoyama Junya , Hoefflin Jens , Ryan Herb , Garbern Jessica , Ho Sui Shannan , Lee Richard , Elwell Hannah , Zhuo Zhu , Ruland Laura , Elcure Alvarez Farid , Frontini Sara , Rodriguez Carreras Yago , Ricci-blair Elisabeth
Keywords: Stem cells, Muscle, cardiac - see Myocardium, Cardiac development, Cardiac regeneration
04 : 30 PM
Sarcomere activation biosensor reveals key functional differences in live cell active states between cardiac and skeletal muscle
Martin Ashley, Metzger Joseph
Final Pr. ID: Mo121
Authors: Martin Ashley , Metzger Joseph
Keywords: Contractility, Troponin, Sarcomere, Muscle, cardiac - see Myocardium, Muscle, skeletal
04 : 30 PM
Titin cleavage induces loss of myocardial tensional homeostasis driving a rapid TGF-beta-independent fibrotic response
Lopez-unzu Miguel, Pricolo Maria Rosaria, Silva-rojas Roberto, Vicente Natalia, Gavilan-herrera Manuel, Velazquez-carreras Diana, Morales-lopez Cristina, Herrero-galan Elias, Alegre-cebollada Jorge
Final Pr. ID: Tu097
Authors: Lopez-unzu Miguel , Pricolo Maria Rosaria , Silva-rojas Roberto , Vicente Natalia , Gavilan-herrera Manuel , Velazquez-carreras Diana , Morales-lopez Cristina , Herrero-galan Elias , Alegre-cebollada Jorge
Keywords: Muscle, cardiac - see Myocardium, Titin, Extracellular matrix, Sarcomere, Molecular biology