American Heart Association
Metabolic Underworld: Mitochondria, Fibrosis, and Cardiac Stress
Moderated Digital Poster Session
Basic Science Zone, Moderated Digital Poster 27
Nov 10th , 09:15 AM - 10:30 AM
09 : 15 AM
Aberrant Splicing of Mitochondrial Dynamics Genes Impairs Cardiac Bioenergetics in Myotonic Dystrophy type I (DM1)
Adesanya Oluwafolajimi, Nabie Pouya, Kalsotra Auinash
Final Pr. ID: MP2768
Authors: Adesanya Oluwafolajimi, Nabie Pouya, Kalsotra Auinash
Keywords: Mitochondrial energetics , Mitochondria , Muscle , cardiac - see Myocardium , Electrophysiology , Energetics
09 : 22 AM
Persistent Metabolic Remodeling Following Alleviation of Afterload Stress in a Preclinical Model, Despite Recovery of Ejection Fraction and Left Ventricle Hypertrophy
Maurya Chandan, Wang Yang, Xie Yujia, Fasano Matthew, Gropler Robert, Carley Andrew, Lewandowski E Douglas
Final Pr. ID: MP2769
Authors: Maurya Chandan, Wang Yang, Xie Yujia, Fasano Matthew, Gropler Robert, Carley Andrew, Lewandowski E Douglas
Keywords: Cardiac metabolism , Cardiac hypertrophy , Aortic stenosis , Energy metabolism
09 : 29 AM
Preservation of Acetyl-Coenzyme A Synthetase 2 Sustains Cytosolic Acetyl-CoA and Protects Against Heart Failure
Sekine Toranosuke, Takeishi Yasuchika, Miura Shunsuke, Okochi Satoshi, Ogawara Ryo, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Nakazato Kazuhiko, Ishida Takafumi
Final Pr. ID: MP2770
Authors: Sekine Toranosuke, Takeishi Yasuchika, Miura Shunsuke, Okochi Satoshi, Ogawara Ryo, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Nakazato Kazuhiko, Ishida Takafumi
Keywords: Mitochondria , Heart failure
09 : 36 AM
Acute Rhythm Change Reveals Atrial-Specific Metabolomic and Lipidomic Alterations in Atrial Fibrillation
Kassar Ahmad, Bockus Lee, Haykal Romanos, Chamoun Nadia, Chahine Yaacoub, Al Yasiri Hala, Hensley Tori, Akoum Nazem
Final Pr. ID: MP2771
Authors: Kassar Ahmad, Bockus Lee, Haykal Romanos, Chamoun Nadia, Chahine Yaacoub, Al Yasiri Hala, Hensley Tori, Akoum Nazem
Keywords: Metabolomics , Lipids , Arrhythmias , Atrial fibrillation
09 : 43 AM
Effect of combined guideline-directed medical therapy and mitochondria-rich extracellular vesicles in a mouse infarct model
Li Jiwen, Ikeda Gentaro, Tzng Eileen, Paleru Amogha, Inoue Hiroyuki, Matsuura Yuka, Koike-ieki Mariko, Yang Phillip
Final Pr. ID: MP2772
Authors: Li Jiwen, Ikeda Gentaro, Tzng Eileen, Paleru Amogha, Inoue Hiroyuki, Matsuura Yuka, Koike-ieki Mariko, Yang Phillip
Keywords: Stem/progenitor cells , Stem cell therapy , Heart failure , Myocardial perfusion
09 : 50 AM
Distinct Roles For CD36 Dependent Versus Independent Transendothelial Delivery And Uptake by Cardiomyocytes Are Revealed by Coordination With Vectorial Acylation by Esterification to Acyl-CoA.
Xie Yujia, Carley Andrew, Goldberg Ira, Lewandowski E Douglas
Final Pr. ID: MP2773
Authors: Xie Yujia, Carley Andrew, Goldberg Ira, Lewandowski E Douglas
Keywords: Cardiac metabolism , Membrane transporters , Endothelial function , Metabolism , Energy metabolism
09 : 57 AM
The inhibition of ATP citrate lyase prevents pathological cardiac fibrosis via the regulation of de novo lipogenesis and histone acetylation
Kuwahara Naoya, Nagao Manabu, Shinohara Masakazu, Kaneshiro Kenta, Ishida Tatsuro, Otake Hiromasa
Final Pr. ID: MP2774
Authors: Kuwahara Naoya, Nagao Manabu, Shinohara Masakazu, Kaneshiro Kenta, Ishida Tatsuro, Otake Hiromasa
Keywords: Fibrosis , Cardiac metabolism , Heart failure
10 : 04 AM
Exacerbation of Doxorubicin-Induced Mitochondrial Dysfunction by the Inhibition of Voltage -Dependent Anion Channel 1 Oligomerization
Miura Shunsuke, Suzuki Yoshinori, Sekine Toranosuke, Okochi Satoshi, Ogawara Ryo, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Ishida Takafumi, Takeishi Yasuchika
Final Pr. ID: MP2775
Authors: Miura Shunsuke, Suzuki Yoshinori, Sekine Toranosuke, Okochi Satoshi, Ogawara Ryo, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Ishida Takafumi, Takeishi Yasuchika
Keywords: Cell physiology , Mitochondria , Reactive oxygen intermediates , Cardio-oncology
Rezaee Malihe, Koleini Navid, Keykhaei Mohammad, Kass David
Final Pr. ID: MP2776
Authors: Rezaee Malihe, Koleini Navid, Keykhaei Mohammad, Kass David
Keywords: Cardiomyopathy , Heart failure , Hypertrophy , Cell signaling , Molecular biology
09 : 15 AM
Aberrant Splicing of Mitochondrial Dynamics Genes Impairs Cardiac Bioenergetics in Myotonic Dystrophy type I (DM1)
Adesanya Oluwafolajimi, Nabie Pouya, Kalsotra Auinash
Final Pr. ID: MP2768
Authors: Adesanya Oluwafolajimi, Nabie Pouya, Kalsotra Auinash
Keywords: Mitochondrial energetics , Mitochondria , Muscle , cardiac - see Myocardium , Electrophysiology , Energetics
09 : 36 AM
Acute Rhythm Change Reveals Atrial-Specific Metabolomic and Lipidomic Alterations in Atrial Fibrillation
Kassar Ahmad, Bockus Lee, Haykal Romanos, Chamoun Nadia, Chahine Yaacoub, Al Yasiri Hala, Hensley Tori, Akoum Nazem
Final Pr. ID: MP2771
Authors: Kassar Ahmad, Bockus Lee, Haykal Romanos, Chamoun Nadia, Chahine Yaacoub, Al Yasiri Hala, Hensley Tori, Akoum Nazem
Keywords: Metabolomics , Lipids , Arrhythmias , Atrial fibrillation
09 : 50 AM
Distinct Roles For CD36 Dependent Versus Independent Transendothelial Delivery And Uptake by Cardiomyocytes Are Revealed by Coordination With Vectorial Acylation by Esterification to Acyl-CoA.
Xie Yujia, Carley Andrew, Goldberg Ira, Lewandowski E Douglas
Final Pr. ID: MP2773
Authors: Xie Yujia, Carley Andrew, Goldberg Ira, Lewandowski E Douglas
Keywords: Cardiac metabolism , Membrane transporters , Endothelial function , Metabolism , Energy metabolism
09 : 43 AM
Effect of combined guideline-directed medical therapy and mitochondria-rich extracellular vesicles in a mouse infarct model
Li Jiwen, Ikeda Gentaro, Tzng Eileen, Paleru Amogha, Inoue Hiroyuki, Matsuura Yuka, Koike-ieki Mariko, Yang Phillip
Final Pr. ID: MP2772
Authors: Li Jiwen, Ikeda Gentaro, Tzng Eileen, Paleru Amogha, Inoue Hiroyuki, Matsuura Yuka, Koike-ieki Mariko, Yang Phillip
Keywords: Stem/progenitor cells , Stem cell therapy , Heart failure , Myocardial perfusion
10 : 04 AM
Exacerbation of Doxorubicin-Induced Mitochondrial Dysfunction by the Inhibition of Voltage -Dependent Anion Channel 1 Oligomerization
Miura Shunsuke, Suzuki Yoshinori, Sekine Toranosuke, Okochi Satoshi, Ogawara Ryo, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Ishida Takafumi, Takeishi Yasuchika
Final Pr. ID: MP2775
Authors: Miura Shunsuke, Suzuki Yoshinori, Sekine Toranosuke, Okochi Satoshi, Ogawara Ryo, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Ishida Takafumi, Takeishi Yasuchika
Keywords: Cell physiology , Mitochondria , Reactive oxygen intermediates , Cardio-oncology
Rezaee Malihe, Koleini Navid, Keykhaei Mohammad, Kass David
Final Pr. ID: MP2776
Authors: Rezaee Malihe, Koleini Navid, Keykhaei Mohammad, Kass David
Keywords: Cardiomyopathy , Heart failure , Hypertrophy , Cell signaling , Molecular biology
09 : 22 AM
Persistent Metabolic Remodeling Following Alleviation of Afterload Stress in a Preclinical Model, Despite Recovery of Ejection Fraction and Left Ventricle Hypertrophy
Maurya Chandan, Wang Yang, Xie Yujia, Fasano Matthew, Gropler Robert, Carley Andrew, Lewandowski E Douglas
Final Pr. ID: MP2769
Authors: Maurya Chandan, Wang Yang, Xie Yujia, Fasano Matthew, Gropler Robert, Carley Andrew, Lewandowski E Douglas
Keywords: Cardiac metabolism , Cardiac hypertrophy , Aortic stenosis , Energy metabolism
09 : 29 AM
Preservation of Acetyl-Coenzyme A Synthetase 2 Sustains Cytosolic Acetyl-CoA and Protects Against Heart Failure
Sekine Toranosuke, Takeishi Yasuchika, Miura Shunsuke, Okochi Satoshi, Ogawara Ryo, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Nakazato Kazuhiko, Ishida Takafumi
Final Pr. ID: MP2770
Authors: Sekine Toranosuke, Takeishi Yasuchika, Miura Shunsuke, Okochi Satoshi, Ogawara Ryo, Yokokawa Tetsuro, Misaka Tomofumi, Oikawa Masayoshi, Nakazato Kazuhiko, Ishida Takafumi
Keywords: Mitochondria , Heart failure
09 : 57 AM
The inhibition of ATP citrate lyase prevents pathological cardiac fibrosis via the regulation of de novo lipogenesis and histone acetylation
Kuwahara Naoya, Nagao Manabu, Shinohara Masakazu, Kaneshiro Kenta, Ishida Tatsuro, Otake Hiromasa
Final Pr. ID: MP2774
Authors: Kuwahara Naoya, Nagao Manabu, Shinohara Masakazu, Kaneshiro Kenta, Ishida Tatsuro, Otake Hiromasa
Keywords: Fibrosis , Cardiac metabolism , Heart failure