American Heart Association
Innovative Approaches and Insights Into HF Therapies
Moderated Digital Poster Session
Clinical Science Zone 2, Moderated Digital Poster 24
Nov 10th , 09:15 AM - 10:15 AM
09 : 15 AM
CRRL094: A novel bispecific designer peptide that protects diabetic heart via AMPK/CIDEC-mediated lipid-lowering effects.
Ma Xiaoyu, Adel Fadi, Singh Jasraj, Malsawmzuali Jc, Zheng Ye, Moroni Dante, Pan Shuchong, Chen Horng
Final Pr. ID: MP2672
Authors: Ma Xiaoyu, Adel Fadi, Singh Jasraj, Malsawmzuali Jc, Zheng Ye, Moroni Dante, Pan Shuchong, Chen Horng
Keywords: Natriuretic peptide , Diabetes Mellitus , Lipids , Cardiomyopathy , Cardiometabolic health
09 : 22 AM
Antibody-conjugated SIS3-loaded polymeric nanoparticles alleviate acute myocardial infarction- and pressure overload-induced cardiac fibrosis by targeting myofibroblasts
Chen Cheng, Pan Qi, Dou Kefei
Final Pr. ID: MP2673
Authors: Chen Cheng, Pan Qi, Dou Kefei
Keywords: Fibrosis , Heart failure , Myocardial infarction
09 : 29 AM
Circulating extracellular vesicle-derived CAPG as a novel molecule associated with pathophysiology and outcomes in heart failure
Okochi Satoshi, Oikawa Masayoshi, Kobayashi Atsushi, Yoshihisa Akiomi, Takeishi Yasuchika, Misaka Tomofumi, Oowada Koji, Kusano Ryota, Suzuki Yoshinori, Ogawara Ryo, Ichimura Shohei, Yokokawa Tetsuro, Sato Takamasa
Final Pr. ID: MP2674
Authors: Okochi Satoshi, Oikawa Masayoshi, Kobayashi Atsushi, Yoshihisa Akiomi, Takeishi Yasuchika, Misaka Tomofumi, Oowada Koji, Kusano Ryota, Suzuki Yoshinori, Ogawara Ryo, Ichimura Shohei, Yokokawa Tetsuro, Sato Takamasa
Keywords: Heart failure , Biomarkers , Molecular , Prognosis
09 : 36 AM
Increased Carnitine Palmitoyltransferase 1a Expression is a Critical Cardioprotective Response to Pathological Stress That Suppresses Gene Programs For Adverse Remodeling Through Non-Conical Signaling and Enables Rescue by Gene Delivery
Carley Andrew, Maurya Chandan, Wang Yang, Lewandowski E Douglas
Final Pr. ID: MP2675
Authors: Carley Andrew, Maurya Chandan, Wang Yang, Lewandowski E Douglas
Keywords: Heart failure , Gene therapy , Remodeling , Cardiac metabolism , Gene expression
09 : 43 AM
CRISPR-Corrected iPSC Models of Pediatric LMNA Cardiomyopathy: A Meta-Analysis of Preclinical Translational Outcomes
Kumar Harendra, Kumari Sonia, Tiwari Angad, Sharma Ashish
Final Pr. ID: MP2676
Authors: Kumar Harendra, Kumari Sonia, Tiwari Angad, Sharma Ashish
Keywords: Heart failure
09 : 50 AM
Restoring LAMP2B in the Heart via Gene-Corrected HSPCs: A Novel Therapy for Danon Disease
Gunes Eren, Cowling Randy, Adler Eric, Tang Zhiyuan, Badell-grau Rafael, Gunes Betul, Laid Lina, Ashman Kiara, Bushway Paul, Gu Yusu, Chequi Stephanie
Final Pr. ID: MP2677
Authors: Gunes Eren, Cowling Randy, Adler Eric, Tang Zhiyuan, Badell-grau Rafael, Gunes Betul, Laid Lina, Ashman Kiara, Bushway Paul, Gu Yusu, Chequi Stephanie
Keywords: Gene therapy , Heart failure , Cardiovascular therapeutics
09 : 57 AM
Calsarcin-1 modulates the muscle LIM protein/Z-disc complex in familial hypertrophic cardiomyopathy
Li Xin, Yue Lixia, Campbell Stuart, Qyang Yibing, Riaz Muhammad, Luo Hangqi, Lu Yinsheng, Liu Yufeng, Li Xianmu, Hoareau Marie, Gokhan Ilhan, Park Jinkyu
Final Pr. ID: MP2678
Authors: Li Xin, Yue Lixia, Campbell Stuart, Qyang Yibing, Riaz Muhammad, Luo Hangqi, Lu Yinsheng, Liu Yufeng, Li Xianmu, Hoareau Marie, Gokhan Ilhan, Park Jinkyu
Keywords: Hypertrophic cardiomyopathy , Sarcomere , Stem cells
10 : 04 AM
Gene positive vs. gene negative clinical and structural outcomes in hypertrophic cardiomyopathy patients: a meta-analysis and systematic review
Weber Maddison, Li-jedras May, Brown Ton Corinna, Kabach Amjad
Final Pr. ID: MP2679
Authors: Weber Maddison, Li-jedras May, Brown Ton Corinna, Kabach Amjad
Keywords: Hypertrophic cardiomyopathy , Left Ventricular , Gene expression , Gene mutations , Outcomes
09 : 22 AM
Antibody-conjugated SIS3-loaded polymeric nanoparticles alleviate acute myocardial infarction- and pressure overload-induced cardiac fibrosis by targeting myofibroblasts
Chen Cheng, Pan Qi, Dou Kefei
Final Pr. ID: MP2673
Authors: Chen Cheng, Pan Qi, Dou Kefei
Keywords: Fibrosis , Heart failure , Myocardial infarction
09 : 57 AM
Calsarcin-1 modulates the muscle LIM protein/Z-disc complex in familial hypertrophic cardiomyopathy
Li Xin, Yue Lixia, Campbell Stuart, Qyang Yibing, Riaz Muhammad, Luo Hangqi, Lu Yinsheng, Liu Yufeng, Li Xianmu, Hoareau Marie, Gokhan Ilhan, Park Jinkyu
Final Pr. ID: MP2678
Authors: Li Xin, Yue Lixia, Campbell Stuart, Qyang Yibing, Riaz Muhammad, Luo Hangqi, Lu Yinsheng, Liu Yufeng, Li Xianmu, Hoareau Marie, Gokhan Ilhan, Park Jinkyu
Keywords: Hypertrophic cardiomyopathy , Sarcomere , Stem cells
09 : 29 AM
Circulating extracellular vesicle-derived CAPG as a novel molecule associated with pathophysiology and outcomes in heart failure
Okochi Satoshi, Oikawa Masayoshi, Kobayashi Atsushi, Yoshihisa Akiomi, Takeishi Yasuchika, Misaka Tomofumi, Oowada Koji, Kusano Ryota, Suzuki Yoshinori, Ogawara Ryo, Ichimura Shohei, Yokokawa Tetsuro, Sato Takamasa
Final Pr. ID: MP2674
Authors: Okochi Satoshi, Oikawa Masayoshi, Kobayashi Atsushi, Yoshihisa Akiomi, Takeishi Yasuchika, Misaka Tomofumi, Oowada Koji, Kusano Ryota, Suzuki Yoshinori, Ogawara Ryo, Ichimura Shohei, Yokokawa Tetsuro, Sato Takamasa
Keywords: Heart failure , Biomarkers , Molecular , Prognosis
09 : 43 AM
CRISPR-Corrected iPSC Models of Pediatric LMNA Cardiomyopathy: A Meta-Analysis of Preclinical Translational Outcomes
Kumar Harendra, Kumari Sonia, Tiwari Angad, Sharma Ashish
Final Pr. ID: MP2676
Authors: Kumar Harendra, Kumari Sonia, Tiwari Angad, Sharma Ashish
Keywords: Heart failure
09 : 15 AM
CRRL094: A novel bispecific designer peptide that protects diabetic heart via AMPK/CIDEC-mediated lipid-lowering effects.
Ma Xiaoyu, Adel Fadi, Singh Jasraj, Malsawmzuali Jc, Zheng Ye, Moroni Dante, Pan Shuchong, Chen Horng
Final Pr. ID: MP2672
Authors: Ma Xiaoyu, Adel Fadi, Singh Jasraj, Malsawmzuali Jc, Zheng Ye, Moroni Dante, Pan Shuchong, Chen Horng
Keywords: Natriuretic peptide , Diabetes Mellitus , Lipids , Cardiomyopathy , Cardiometabolic health
10 : 04 AM
Gene positive vs. gene negative clinical and structural outcomes in hypertrophic cardiomyopathy patients: a meta-analysis and systematic review
Weber Maddison, Li-jedras May, Brown Ton Corinna, Kabach Amjad
Final Pr. ID: MP2679
Authors: Weber Maddison, Li-jedras May, Brown Ton Corinna, Kabach Amjad
Keywords: Hypertrophic cardiomyopathy , Left Ventricular , Gene expression , Gene mutations , Outcomes
09 : 36 AM
Increased Carnitine Palmitoyltransferase 1a Expression is a Critical Cardioprotective Response to Pathological Stress That Suppresses Gene Programs For Adverse Remodeling Through Non-Conical Signaling and Enables Rescue by Gene Delivery
Carley Andrew, Maurya Chandan, Wang Yang, Lewandowski E Douglas
Final Pr. ID: MP2675
Authors: Carley Andrew, Maurya Chandan, Wang Yang, Lewandowski E Douglas
Keywords: Heart failure , Gene therapy , Remodeling , Cardiac metabolism , Gene expression
09 : 50 AM
Restoring LAMP2B in the Heart via Gene-Corrected HSPCs: A Novel Therapy for Danon Disease
Gunes Eren, Cowling Randy, Adler Eric, Tang Zhiyuan, Badell-grau Rafael, Gunes Betul, Laid Lina, Ashman Kiara, Bushway Paul, Gu Yusu, Chequi Stephanie
Final Pr. ID: MP2677
Authors: Gunes Eren, Cowling Randy, Adler Eric, Tang Zhiyuan, Badell-grau Rafael, Gunes Betul, Laid Lina, Ashman Kiara, Bushway Paul, Gu Yusu, Chequi Stephanie
Keywords: Gene therapy , Heart failure , Cardiovascular therapeutics