American Heart Association
Epidemiology Meets Mechanism: Translational Insights into Cardiometabolic Mortality
Moderated Digital Poster Session
Basic Science Zone, Moderated Digital Poster 26
Nov 8th , 01:45 PM - 03:00 PM
01 : 45 PM
Cardiomyocyte-Specific TFEB Deletion Induces Age-Dependent Heart Failure, Exacerbated by Starvation
Doermann Niklas, Hammer Elke, Schlueter Rabea, Völker Uwe, Fielitz Jens
Final Pr. ID: MP1136
Authors: Doermann Niklas, Hammer Elke, Schlueter Rabea, Völker Uwe, Fielitz Jens
Keywords: Heart failure , Cardiac metabolism , Cardiovascular , Metabolism , Metabolomics
01 : 52 PM
Selective Reduction of Mitochondrial GAPDH in Left Ventricular Myocardium of Dogs with Heart Failure
Gupta Ramesh, Szekely Kristina, Zhang Kefei, Lanfear David, Sabbah Hani
Final Pr. ID: MP1137
Authors: Gupta Ramesh, Szekely Kristina, Zhang Kefei, Lanfear David, Sabbah Hani
Keywords: Mitochondria , Heart failure , Myocardium , Mitochondrial energetics , Signal transduction
01 : 59 PM
Finerenone Attenuates Cardiac Hypertrophy in a Mouse Model of HFpEF by Modulating Glucocorticoid and Mineralocorticoid Receptor Signaling
Morikawa Kei, Nagakura Takumi, Fujiyama Akira, Yuquing Xu, Hanatani Shinsuke, Izumiya Yasuhiro, Arima Yuichiro, Tsujita Kenichi
Final Pr. ID: MP1138
Authors: Morikawa Kei, Nagakura Takumi, Fujiyama Akira, Yuquing Xu, Hanatani Shinsuke, Izumiya Yasuhiro, Arima Yuichiro, Tsujita Kenichi
Keywords: Heart failure , Pharmacology , Metabolism , Gene expression
02 : 06 PM
Low-Dose Semaglutide Attenuates Cardiac Lipid Content and Hepatic Steatosis in Cardiometabolic HFpEF: Weight Loss Independent Actions of GLP-1 Receptor Activation
Elbatreek Mahmoud, Li Zhen, Shah Sanjiv, Allerton Timothy, Yang Hsin-jung, Lefer David, Goodchild Traci
Final Pr. ID: MP1139
Authors: Elbatreek Mahmoud, Li Zhen, Shah Sanjiv, Allerton Timothy, Yang Hsin-jung, Lefer David, Goodchild Traci
Keywords: HFpEF , Heart failure , Lipids
02 : 13 PM
Rising Mortality at the Crossroads of Endocrine and Cardiovascular Disease: National Trends in Hyperthyroidism and Hypertension (1999–2020)
Khan Ayesha, Shamshad Talha, Hemida Mohamed Fawzi, Ibrahim Alyaa, Alsaadi Mustafa, Shahriar Zahin, Patel Krish, Hashmi Moiz Ul Haq, Salman Hassan Syed Muhammed, Bashir Sara
Final Pr. ID: MP1140
Authors: Khan Ayesha, Shamshad Talha, Hemida Mohamed Fawzi, Ibrahim Alyaa, Alsaadi Mustafa, Shahriar Zahin, Patel Krish, Hashmi Moiz Ul Haq, Salman Hassan Syed Muhammed, Bashir Sara
Keywords: Thyroid hormones , Heart failure , Mortality , Population science , Cardiometabolic health
02 : 20 PM
Dysregulated Lactate Metabolism in Cardiomyocytes Drives Immune Checkpoint Inhibitor- Associated Myocarditis
Xiong Shijie, Qian Jiang, Zou Yan, Wan Junhong, Yuan Ludong, Li Jingwei, Cai Weibin, Liu Mengying, Tan Jing, Huang Tongsheng, Shen Conghui, Wu Teng, Ren Honglin, Fu Xinlu, Ji Yuanjun
Final Pr. ID: MP1141
Authors: Xiong Shijie, Qian Jiang, Zou Yan, Wan Junhong, Yuan Ludong, Li Jingwei, Cai Weibin, Liu Mengying, Tan Jing, Huang Tongsheng, Shen Conghui, Wu Teng, Ren Honglin, Fu Xinlu, Ji Yuanjun
Keywords: Metabolism , Cardiovascular disease
02 : 27 PM
Targeting SARM1 NAD hydrolase for therapy of cardiometabolic diseases by regulating mitophagy and mitochondrial respiration
Nizami Hina Lateef, Minor Keaton, Gorecki Ignacy, Light Christine, Chiao Ying Ann, Lee Chi Fung
Final Pr. ID: MP1142
Authors: Nizami Hina Lateef, Minor Keaton, Gorecki Ignacy, Light Christine, Chiao Ying Ann, Lee Chi Fung
Keywords: Cardiometabolic health , Mitochondria , Heart failure , Metabolism
02 : 34 PM
SARM1-Associated NAD Loss Links Hypoxic Signaling to Metabolic Reprogramming in Diabetic Cardiomyopathy
Minor Keaton, Singhal Pratyaksh, Chi Jinhua, Szybowska Patrycja, Nizami Hina Lateef, Gu Haiwei, Chiao Ying Ann, Lee Chi Fung
Final Pr. ID: MP1143
Authors: Minor Keaton, Singhal Pratyaksh, Chi Jinhua, Szybowska Patrycja, Nizami Hina Lateef, Gu Haiwei, Chiao Ying Ann, Lee Chi Fung
Keywords: Metabolism , CADASIL
02 : 41 PM
Development of a Metabolomics-Based Model for Predicting Atrial Fibrillation: A Prospective Case-Cohort Study
Mizuno Atsushi, Sato Takaaki, Nojima Masanori, Aoki Yutaka, Watanabe Makoto, Koshizaka Takuya, Ohtake Junya, Kojima Fumitsugu, Kimura Takeshi, Kumakura Yasuhisa
Final Pr. ID: MP1144
Authors: Mizuno Atsushi, Sato Takaaki, Nojima Masanori, Aoki Yutaka, Watanabe Makoto, Koshizaka Takuya, Ohtake Junya, Kojima Fumitsugu, Kimura Takeshi, Kumakura Yasuhisa
Keywords: Metabolomics , Atrial arrhythmias , Arrhythmias , Prediction model
02 : 48 PM
Cardiac Branched-Chain Amino Acid Metabolic Dysfunction in a Novel Model of Diabetic Cardiomyopathy
Nagao Manabu, Asakura Junko, Hosooka Tetsuya, Kuwahara Naoya, Kaneshiro Kenta, Tanaka Hidekazu, Ishida Tatsuro, Otake Hiromasa, Shinohara Masakazu
Final Pr. ID: MP1145
Authors: Nagao Manabu, Asakura Junko, Hosooka Tetsuya, Kuwahara Naoya, Kaneshiro Kenta, Tanaka Hidekazu, Ishida Tatsuro, Otake Hiromasa, Shinohara Masakazu
Keywords: Cardiac hypertrophy , Cardiac metabolism , Diabetes Mellitus , Insulin resistance , Heart failure
02 : 48 PM
Cardiac Branched-Chain Amino Acid Metabolic Dysfunction in a Novel Model of Diabetic Cardiomyopathy
Nagao Manabu, Asakura Junko, Hosooka Tetsuya, Kuwahara Naoya, Kaneshiro Kenta, Tanaka Hidekazu, Ishida Tatsuro, Otake Hiromasa, Shinohara Masakazu
Final Pr. ID: MP1145
Authors: Nagao Manabu, Asakura Junko, Hosooka Tetsuya, Kuwahara Naoya, Kaneshiro Kenta, Tanaka Hidekazu, Ishida Tatsuro, Otake Hiromasa, Shinohara Masakazu
Keywords: Cardiac hypertrophy , Cardiac metabolism , Diabetes Mellitus , Insulin resistance , Heart failure
01 : 45 PM
Cardiomyocyte-Specific TFEB Deletion Induces Age-Dependent Heart Failure, Exacerbated by Starvation
Doermann Niklas, Hammer Elke, Schlueter Rabea, Völker Uwe, Fielitz Jens
Final Pr. ID: MP1136
Authors: Doermann Niklas, Hammer Elke, Schlueter Rabea, Völker Uwe, Fielitz Jens
Keywords: Heart failure , Cardiac metabolism , Cardiovascular , Metabolism , Metabolomics
02 : 41 PM
Development of a Metabolomics-Based Model for Predicting Atrial Fibrillation: A Prospective Case-Cohort Study
Mizuno Atsushi, Sato Takaaki, Nojima Masanori, Aoki Yutaka, Watanabe Makoto, Koshizaka Takuya, Ohtake Junya, Kojima Fumitsugu, Kimura Takeshi, Kumakura Yasuhisa
Final Pr. ID: MP1144
Authors: Mizuno Atsushi, Sato Takaaki, Nojima Masanori, Aoki Yutaka, Watanabe Makoto, Koshizaka Takuya, Ohtake Junya, Kojima Fumitsugu, Kimura Takeshi, Kumakura Yasuhisa
Keywords: Metabolomics , Atrial arrhythmias , Arrhythmias , Prediction model
02 : 20 PM
Dysregulated Lactate Metabolism in Cardiomyocytes Drives Immune Checkpoint Inhibitor- Associated Myocarditis
Xiong Shijie, Qian Jiang, Zou Yan, Wan Junhong, Yuan Ludong, Li Jingwei, Cai Weibin, Liu Mengying, Tan Jing, Huang Tongsheng, Shen Conghui, Wu Teng, Ren Honglin, Fu Xinlu, Ji Yuanjun
Final Pr. ID: MP1141
Authors: Xiong Shijie, Qian Jiang, Zou Yan, Wan Junhong, Yuan Ludong, Li Jingwei, Cai Weibin, Liu Mengying, Tan Jing, Huang Tongsheng, Shen Conghui, Wu Teng, Ren Honglin, Fu Xinlu, Ji Yuanjun
Keywords: Metabolism , Cardiovascular disease
01 : 59 PM
Finerenone Attenuates Cardiac Hypertrophy in a Mouse Model of HFpEF by Modulating Glucocorticoid and Mineralocorticoid Receptor Signaling
Morikawa Kei, Nagakura Takumi, Fujiyama Akira, Yuquing Xu, Hanatani Shinsuke, Izumiya Yasuhiro, Arima Yuichiro, Tsujita Kenichi
Final Pr. ID: MP1138
Authors: Morikawa Kei, Nagakura Takumi, Fujiyama Akira, Yuquing Xu, Hanatani Shinsuke, Izumiya Yasuhiro, Arima Yuichiro, Tsujita Kenichi
Keywords: Heart failure , Pharmacology , Metabolism , Gene expression
02 : 06 PM
Low-Dose Semaglutide Attenuates Cardiac Lipid Content and Hepatic Steatosis in Cardiometabolic HFpEF: Weight Loss Independent Actions of GLP-1 Receptor Activation
Elbatreek Mahmoud, Li Zhen, Shah Sanjiv, Allerton Timothy, Yang Hsin-jung, Lefer David, Goodchild Traci
Final Pr. ID: MP1139
Authors: Elbatreek Mahmoud, Li Zhen, Shah Sanjiv, Allerton Timothy, Yang Hsin-jung, Lefer David, Goodchild Traci
Keywords: HFpEF , Heart failure , Lipids
02 : 13 PM
Rising Mortality at the Crossroads of Endocrine and Cardiovascular Disease: National Trends in Hyperthyroidism and Hypertension (1999–2020)
Khan Ayesha, Shamshad Talha, Hemida Mohamed Fawzi, Ibrahim Alyaa, Alsaadi Mustafa, Shahriar Zahin, Patel Krish, Hashmi Moiz Ul Haq, Salman Hassan Syed Muhammed, Bashir Sara
Final Pr. ID: MP1140
Authors: Khan Ayesha, Shamshad Talha, Hemida Mohamed Fawzi, Ibrahim Alyaa, Alsaadi Mustafa, Shahriar Zahin, Patel Krish, Hashmi Moiz Ul Haq, Salman Hassan Syed Muhammed, Bashir Sara
Keywords: Thyroid hormones , Heart failure , Mortality , Population science , Cardiometabolic health
02 : 34 PM
SARM1-Associated NAD Loss Links Hypoxic Signaling to Metabolic Reprogramming in Diabetic Cardiomyopathy
Minor Keaton, Singhal Pratyaksh, Chi Jinhua, Szybowska Patrycja, Nizami Hina Lateef, Gu Haiwei, Chiao Ying Ann, Lee Chi Fung
Final Pr. ID: MP1143
Authors: Minor Keaton, Singhal Pratyaksh, Chi Jinhua, Szybowska Patrycja, Nizami Hina Lateef, Gu Haiwei, Chiao Ying Ann, Lee Chi Fung
Keywords: Metabolism , CADASIL
01 : 52 PM
Selective Reduction of Mitochondrial GAPDH in Left Ventricular Myocardium of Dogs with Heart Failure
Gupta Ramesh, Szekely Kristina, Zhang Kefei, Lanfear David, Sabbah Hani
Final Pr. ID: MP1137
Authors: Gupta Ramesh, Szekely Kristina, Zhang Kefei, Lanfear David, Sabbah Hani
Keywords: Mitochondria , Heart failure , Myocardium , Mitochondrial energetics , Signal transduction
02 : 27 PM
Targeting SARM1 NAD hydrolase for therapy of cardiometabolic diseases by regulating mitophagy and mitochondrial respiration
Nizami Hina Lateef, Minor Keaton, Gorecki Ignacy, Light Christine, Chiao Ying Ann, Lee Chi Fung
Final Pr. ID: MP1142
Authors: Nizami Hina Lateef, Minor Keaton, Gorecki Ignacy, Light Christine, Chiao Ying Ann, Lee Chi Fung
Keywords: Cardiometabolic health , Mitochondria , Heart failure , Metabolism