Showing Results from 1 to 12 of 221.
04 : 30 PM
3-Mercaptopyruvate Sulfurtransferase is a Critical Regulator of Branched-Chain Amino Acid Catabolism in Cardiometabolic HFpEF
Li Zhen, Doiron Jake, Xia Huijing, Lapenna Kyle, Sharp Thomas, Yu Xiaoman, Nagahara Noriyuki, Goodchild Traci, Lefer David
Final Pr. ID: Mo101
Authors: Li Zhen , Doiron Jake , Xia Huijing , Lapenna Kyle , Sharp Thomas , Yu Xiaoman , Nagahara Noriyuki , Goodchild Traci , Lefer David
Keywords: HFpEF, Cardiac metabolism, Mitochondria
12 : 15 PM
A DHX38 Spliceosomal Mutation Impairs MYC Signaling, Cardiac Transcriptome Splicing, and Leads to Diastolic Dysfunction
Iwanski Jessika, Sarvagalla Sailu, Methawasin Mei, Van Den Berg Marloes, Churko Jared
Final Pr. ID: MP2725
Authors: Iwanski Jessika , Sarvagalla Sailu , Methawasin Mei , Van Den Berg Marloes , Churko Jared
Keywords: Cardiomyopathy, Transcriptomics, Proteomics, Diastolic function, HFpEF
02 : 30 PM
A Highly Selective and Orally Available HDAC6 Inhibitor, EKZ-102, Ameliorates Cardiac Dysfunction and Exercise Intolerance in Cardiometabolic HFpEF
Elbatreek Mahmoud, Goodchild Traci, Lefer David, Evans Lauren, Richardson Thomas, James Rebecca, Schroeder Frederick, Wang Jianhong, Luterman Jim, Gilbert Tonya, Fisher Richard
Final Pr. ID: LBP24
Authors: Elbatreek Mahmoud , Goodchild Traci , Lefer David , Evans Lauren , Richardson Thomas , James Rebecca , Schroeder Frederick , Wang Jianhong , Luterman Jim , Gilbert Tonya , Fisher Richard
Keywords: Heart failure, HFpEF, Cardiomyopathy
02 : 30 PM
A mechanism whereby SGLT2 inhibitor dapagliflozin reverses cardiac diastolic dysfunction in a model of HFpEF
Liu Man, Liu Hong, Kang Gyeoung-jin, Kim Eunji, Neumann Mitchell, Johnson Madeline, Murikinati Ruthvika, Dudley Samuel
Final Pr. ID: LBP27
Authors: Liu Man , Liu Hong , Kang Gyeoung-jin , Kim Eunji , Neumann Mitchell , Johnson Madeline , Murikinati Ruthvika , Dudley Samuel
Keywords: HFpEF, Cardioprotective drugs, Diastolic function, Inflammation, Membrane transporters
09 : 30 AM
A Rare Cause of Recurrent Heart Failure Exacerbations After Transcatheter Aortic Valve Replacement: Ventricular Septal Defect and Significant Paravalvular Leak
Medina Jesse, Vincent Louis, Rodriguez Ferreira Esteban, Spence-miller Shanice, Fernandez Joel, Colombo Rosario, Calfa Marian
Final Pr. ID: MDP1356
Authors: Medina Jesse , Vincent Louis , Rodriguez Ferreira Esteban , Spence-miller Shanice , Fernandez Joel , Colombo Rosario , Calfa Marian
Keywords: Transcatheter aortic valve implantation, Heart failure, adult, HFpEF, Hemodynamics, Cardiovascular imaging
03 : 22 PM
A RETRO-ENANTIOMER OF ANGIOTENSIN-(1-9) PREVENTS THE DEVELOPMENT OF HEART FAILURE WITH PRESERVED EJECTION FRACTION.
Ocaranza Maria Paz, Jimenez Veronica, Yanez Osvaldo, Jalil Jorge, Venegas Camilo, Candia Camila, Hermoso Marcela, Gabrielli Luigi, Morales Javier, Oyarzun Felipe, Torres Cristian, Lillo Pablo
Final Pr. ID: MP1671
Authors: Ocaranza Maria Paz , Jimenez Veronica , Yanez Osvaldo , Jalil Jorge , Venegas Camilo , Candia Camila , Hermoso Marcela , Gabrielli Luigi , Morales Javier , Oyarzun Felipe , Torres Cristian , Lillo Pablo
Keywords: Cardiovascular disease prevention, Cardioprotection, HFpEF, Renin-Aldosterone-Angiotensin (Raa)
03 : 15 PM
A short version of HFD/L-NAME mouse model enabling time-effective proof of concept studies to evaluate drugs targeting the cardiometabolic and mild hypertension associated HFpEF phenotype.
Assaly Rana, Dubroca Caroline, Waget Aurelie, Perrier Kevin, Sulpice Thierry
Final Pr. ID: Su1071
Authors: Assaly Rana , Dubroca Caroline , Waget Aurelie , Perrier Kevin , Sulpice Thierry
Keywords: HFpEF, Metabolic syndrome, Hypertension, Obesity, Experimental heart failure
Nehra Sarita, Selvam Sabariya, Anand Amit, Luettgen Joseph, Gulia Jyoti, Dokania Manoj, Gupta Ankit, Garcia Ricardo, Dudhgaonkar Shailesh, Mazumder Tagore Debarati, Ck Neethu, Wagh Somnath, Kale Prajakta
Final Pr. ID: Tu056
Authors: Nehra Sarita , Selvam Sabariya , Anand Amit , Luettgen Joseph , Gulia Jyoti , Dokania Manoj , Gupta Ankit , Garcia Ricardo , Dudhgaonkar Shailesh , Mazumder Tagore Debarati , Ck Neethu , Wagh Somnath , Kale Prajakta
Keywords: Cardiac hypertrophy, Cardiovascular therapeutics, Diastolic function, Heart failure, HFpEF
04 : 30 PM
Aberrant Trans- and De- Nitrosylation Underpins Nitrosative Stress in Cardiometabolic HFpEF
Li Zhen, Borch Jensen Martin, Vondriska Thomas, Lefer David, Gehred Natalie, Gromova Tatiana, Lapenna Kyle, Sharp Thomas, Chen Jingshu, Shambhu Smitha, Yu Xiaoman, Goodchild Traci
Final Pr. ID: Mo103
Authors: Li Zhen , Borch Jensen Martin , Vondriska Thomas , Lefer David , Gehred Natalie , Gromova Tatiana , Lapenna Kyle , Sharp Thomas , Chen Jingshu , Shambhu Smitha , Yu Xiaoman , Goodchild Traci
Keywords: HFpEF, Nitric oxide, Nitric oxide synthase, Cell signaling, Rural Health
Tagata Kento, Yutaro Nomoto, Tao Koji, Kataoka Tetsuro, Ohishi Mitsuru
Final Pr. ID: Mo2082
Authors: Tagata Kento , Yutaro Nomoto , Tao Koji , Kataoka Tetsuro , Ohishi Mitsuru
Keywords: Amyloidosis, Cardiomyopathy, HFpEF
10 : 11 AM
Accelerated Pacing Reverses Ventricular Stiffening in a Rodent Model of Diastolic Dysfunction
Kabir Raihan, Hancock Emmaleigh, Wetzel Melinda, Shrier Julia, Palmer Bradley, Habel Nicole, Caporizzo Matthew
Final Pr. ID: MP2713
Authors: Kabir Raihan , Hancock Emmaleigh , Wetzel Melinda , Shrier Julia , Palmer Bradley , Habel Nicole , Caporizzo Matthew
Keywords: HFpEF, Pacing, Pressure – volume relation, Ventricular remodeling, Myocardium
10 : 30 AM
Active Left Atrial Ejection Fraction as a Non-Invasive Prognostic Marker in Left Heart Failure associated Pulmonary Hypertension
Zhou Di, Xin Li, Liu Zhihong, Lu Minjie
Final Pr. ID: Sa4129
Authors: Zhou Di , Xin Li , Liu Zhihong , Lu Minjie
Keywords: Pulmonary hypertension, HFpEF, Heart failure, Cardiac MRI, Cardiovascular imaging