American Heart Association
Decoding the Molecular Basis of Disease: Using OMICS to Understand Pulmonary Vascular Disease
Moderated Digital Poster Session
Clinical Science Zone 2, Moderated Digital Poster 22
Nov 8th , 10:45 AM - 12:00 PM
10 : 45 AM
Single-Cell Resolution Spatial Transcriptomics Reveals Cellular and Molecular Dysregulation in Human Pulmonary Arterial Hypertension
Liu Tianhao, Zhao Hanqiu, Hong Jason, Chen Wei, Dai Zhiyu
Final Pr. ID: MP938
Authors: Liu Tianhao, Zhao Hanqiu, Hong Jason, Chen Wei, Dai Zhiyu
Keywords: Pulmonary hypertension , Biomarkers , Pulmonary circulation
10 : 52 AM
Multi-omics Profiling Defines the Cellular and Molecular Evolution of Progressive Right Ventricular Dysfunction
Mendelson Jenna, Sternbach Jacob, Moon Ryan, Kazmirczak Felipe, Prins Kurt
Final Pr. ID: MP939
Authors: Mendelson Jenna, Sternbach Jacob, Moon Ryan, Kazmirczak Felipe, Prins Kurt
Keywords: Right Ventricular Dysfunction , Metabolism , Inflammation , Proteomics
10 : 59 AM
Human Single-Cell Atlas of Pulmonary Arterial Hypertension Reveals a Novel Arterial Endothelial Subtype Involved in Plexiform Lesion Pathogenesis
Zhao Hanqiu, Hong Jason, Fallon Michael, Dai Zhiyu
Final Pr. ID: MP940
Authors: Zhao Hanqiu, Hong Jason, Fallon Michael, Dai Zhiyu
Keywords: Pulmonary hypertension , Endothelial , Transcriptomics , Pulmonary vascular biology
11 : 06 AM
A single-cell atlas of the human PAH lung identifies ITGA9 as a candidate regulator of fibroblast activation and vascular remodeling
Brownstein Adam, Wong Brenda, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh, Hong Jason
Final Pr. ID: MP941
Authors: Brownstein Adam, Wong Brenda, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh, Hong Jason
Keywords: Pulmonary hypertension , Pulmonary circulation
11 : 13 AM
Proteomics analysis identifies sub-phenotypes amongst clinically similar patients with Idiopathic Pulmonary Arterial Hypertension
Ruan Peifeng, Manlhiot Cedric, Austin Eric, Nichols Bill, Everett Allen, Griffiths Megan
Final Pr. ID: MP942
Authors: Ruan Peifeng, Manlhiot Cedric, Austin Eric, Nichols Bill, Everett Allen, Griffiths Megan
Keywords: Pulmonary hypertension , Pulmonary vascular biology , Proteomics
11 : 20 AM
Dissecting Cellular Spatial Relationships in Severe Pulmonary Hypertension Using High-Resolution Spatial Transcriptomics
Liu Tianhao, Zhao Hanqiu, Zhao Chongyue, Liu Bin, Qiu Shenfeng, Chen Wei, Dai Zhiyu
Final Pr. ID: MP943
Authors: Liu Tianhao, Zhao Hanqiu, Zhao Chongyue, Liu Bin, Qiu Shenfeng, Chen Wei, Dai Zhiyu
Keywords: Pulmonary hypertension , Biomedical informatics , Pulmonary artery
Byrd Carly, Austin Eric, Hassoun Paul, Everett Allen, Schramm Jennifer, Yang Jun, Griffiths Megan, Damico Rachel, Simpson Catherine, Kolb Todd, Nichols Bill, Ivy Dunbar
Final Pr. ID: MP944
Authors: Byrd Carly, Austin Eric, Hassoun Paul, Everett Allen, Schramm Jennifer, Yang Jun, Griffiths Megan, Damico Rachel, Simpson Catherine, Kolb Todd, Nichols Bill, Ivy Dunbar
Keywords: Pulmonary hypertension , Biomarkers
11 : 34 AM
The Novel ErbB4 Agonist JK07 Modulates Gene Expression in Key Cardiac Cells. Insights from Single-Nuclei Transcriptomics in a Murine Heart Failure Model
Civati Celine, Van Den Bogaert Siel, Goovaerts Bo, Cools Julie, Mcnally Jonathan, Dong Jijun, De Keulenaer Gilles, Segers Vincent
Final Pr. ID: MP945
Authors: Civati Celine, Van Den Bogaert Siel, Goovaerts Bo, Cools Julie, Mcnally Jonathan, Dong Jijun, De Keulenaer Gilles, Segers Vincent
Keywords: Heart failure , Transcriptomics
11 : 41 AM
Using High-throughput Proteome-wide Analysis to Discover Clinical Biomarkers of Pediatric Pulmonary Arterial Hypertension
Ng Qimin, Ivy Dunbar, Chinni Bhargava, Manlhiot Cedric, Nichols Bill, Barnes Allan, Griffiths Megan, Yang Jun, Everett Allen
Final Pr. ID: MP946
Authors: Ng Qimin, Ivy Dunbar, Chinni Bhargava, Manlhiot Cedric, Nichols Bill, Barnes Allan, Griffiths Megan, Yang Jun, Everett Allen
Keywords: Pediatric cardiology , Pulmonary hypertension , Biomarkers , Proteomics
11 : 48 AM
Transcriptomic profiling of plasma microRNA reveals circulating biomarkers of transthyretin cardiac amyloidosis and dysregulated signaling pathways.
Boursiquot Brian, Lu Ree, Akita Keitaro, Teruya Sergio, Bampatsias Dimitrios, Mirabal Alfonsina, Fifer Michael, Maurer Mathew, Shimada Yuichi
Final Pr. ID: MP947
Authors: Boursiquot Brian, Lu Ree, Akita Keitaro, Teruya Sergio, Bampatsias Dimitrios, Mirabal Alfonsina, Fifer Michael, Maurer Mathew, Shimada Yuichi
Keywords: Amyloidosis , Transcriptomics , Biomarkers
11 : 06 AM
A single-cell atlas of the human PAH lung identifies ITGA9 as a candidate regulator of fibroblast activation and vascular remodeling
Brownstein Adam, Wong Brenda, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh, Hong Jason
Final Pr. ID: MP941
Authors: Brownstein Adam, Wong Brenda, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh, Hong Jason
Keywords: Pulmonary hypertension , Pulmonary circulation
11 : 20 AM
Dissecting Cellular Spatial Relationships in Severe Pulmonary Hypertension Using High-Resolution Spatial Transcriptomics
Liu Tianhao, Zhao Hanqiu, Zhao Chongyue, Liu Bin, Qiu Shenfeng, Chen Wei, Dai Zhiyu
Final Pr. ID: MP943
Authors: Liu Tianhao, Zhao Hanqiu, Zhao Chongyue, Liu Bin, Qiu Shenfeng, Chen Wei, Dai Zhiyu
Keywords: Pulmonary hypertension , Biomedical informatics , Pulmonary artery
10 : 59 AM
Human Single-Cell Atlas of Pulmonary Arterial Hypertension Reveals a Novel Arterial Endothelial Subtype Involved in Plexiform Lesion Pathogenesis
Zhao Hanqiu, Hong Jason, Fallon Michael, Dai Zhiyu
Final Pr. ID: MP940
Authors: Zhao Hanqiu, Hong Jason, Fallon Michael, Dai Zhiyu
Keywords: Pulmonary hypertension , Endothelial , Transcriptomics , Pulmonary vascular biology
10 : 52 AM
Multi-omics Profiling Defines the Cellular and Molecular Evolution of Progressive Right Ventricular Dysfunction
Mendelson Jenna, Sternbach Jacob, Moon Ryan, Kazmirczak Felipe, Prins Kurt
Final Pr. ID: MP939
Authors: Mendelson Jenna, Sternbach Jacob, Moon Ryan, Kazmirczak Felipe, Prins Kurt
Keywords: Right Ventricular Dysfunction , Metabolism , Inflammation , Proteomics
11 : 13 AM
Proteomics analysis identifies sub-phenotypes amongst clinically similar patients with Idiopathic Pulmonary Arterial Hypertension
Ruan Peifeng, Manlhiot Cedric, Austin Eric, Nichols Bill, Everett Allen, Griffiths Megan
Final Pr. ID: MP942
Authors: Ruan Peifeng, Manlhiot Cedric, Austin Eric, Nichols Bill, Everett Allen, Griffiths Megan
Keywords: Pulmonary hypertension , Pulmonary vascular biology , Proteomics
Byrd Carly, Austin Eric, Hassoun Paul, Everett Allen, Schramm Jennifer, Yang Jun, Griffiths Megan, Damico Rachel, Simpson Catherine, Kolb Todd, Nichols Bill, Ivy Dunbar
Final Pr. ID: MP944
Authors: Byrd Carly, Austin Eric, Hassoun Paul, Everett Allen, Schramm Jennifer, Yang Jun, Griffiths Megan, Damico Rachel, Simpson Catherine, Kolb Todd, Nichols Bill, Ivy Dunbar
Keywords: Pulmonary hypertension , Biomarkers
10 : 45 AM
Single-Cell Resolution Spatial Transcriptomics Reveals Cellular and Molecular Dysregulation in Human Pulmonary Arterial Hypertension
Liu Tianhao, Zhao Hanqiu, Hong Jason, Chen Wei, Dai Zhiyu
Final Pr. ID: MP938
Authors: Liu Tianhao, Zhao Hanqiu, Hong Jason, Chen Wei, Dai Zhiyu
Keywords: Pulmonary hypertension , Biomarkers , Pulmonary circulation
11 : 34 AM
The Novel ErbB4 Agonist JK07 Modulates Gene Expression in Key Cardiac Cells. Insights from Single-Nuclei Transcriptomics in a Murine Heart Failure Model
Civati Celine, Van Den Bogaert Siel, Goovaerts Bo, Cools Julie, Mcnally Jonathan, Dong Jijun, De Keulenaer Gilles, Segers Vincent
Final Pr. ID: MP945
Authors: Civati Celine, Van Den Bogaert Siel, Goovaerts Bo, Cools Julie, Mcnally Jonathan, Dong Jijun, De Keulenaer Gilles, Segers Vincent
Keywords: Heart failure , Transcriptomics
11 : 48 AM
Transcriptomic profiling of plasma microRNA reveals circulating biomarkers of transthyretin cardiac amyloidosis and dysregulated signaling pathways.
Boursiquot Brian, Lu Ree, Akita Keitaro, Teruya Sergio, Bampatsias Dimitrios, Mirabal Alfonsina, Fifer Michael, Maurer Mathew, Shimada Yuichi
Final Pr. ID: MP947
Authors: Boursiquot Brian, Lu Ree, Akita Keitaro, Teruya Sergio, Bampatsias Dimitrios, Mirabal Alfonsina, Fifer Michael, Maurer Mathew, Shimada Yuichi
Keywords: Amyloidosis , Transcriptomics , Biomarkers
11 : 41 AM
Using High-throughput Proteome-wide Analysis to Discover Clinical Biomarkers of Pediatric Pulmonary Arterial Hypertension
Ng Qimin, Ivy Dunbar, Chinni Bhargava, Manlhiot Cedric, Nichols Bill, Barnes Allan, Griffiths Megan, Yang Jun, Everett Allen
Final Pr. ID: MP946
Authors: Ng Qimin, Ivy Dunbar, Chinni Bhargava, Manlhiot Cedric, Nichols Bill, Barnes Allan, Griffiths Megan, Yang Jun, Everett Allen
Keywords: Pediatric cardiology , Pulmonary hypertension , Biomarkers , Proteomics