American Heart Association
When Cells and Molecules Go Bad: Molecular Mechanisms of Pulmonary Vascular Disease
Abstract Poster Session
Zone 4
Nov 17th , 03:15 PM - 04:15 PM
03 : 15 PM
MHCIIhiLYVE1loCCR2hi Interstitial Macrophages Promote Medial Fibrosis in Pulmonary Arterioles and Contribute to Pulmonary Hypertension
Qiu Fan, Miao Hao-ran, Hui Hong-liang, Yangui Lin, Li Hua-ming, Li Dan, Luo Min, Ong Sang-bing, Hu Xue-fei, Jiang Bo, Zhang Yi-qian
Final Pr. ID: Su4175
Authors: Qiu Fan, Miao Hao-ran, Hui Hong-liang, Yangui Lin, Li Hua-ming, Li Dan, Luo Min, Ong Sang-bing, Hu Xue-fei, Jiang Bo, Zhang Yi-qian
Keywords: Pulmonary hypertension , Pulmonary vascular biology , Inflammation and inflammatory markers
03 : 15 PM
The critical role of CD206+ pro-PAH macrophages in contributing to severe pulmonary arterial hypertension and obliterative vascular remodeling
Dai Jingbo
Final Pr. ID: Su4181
Authors: Dai Jingbo
Keywords: Pulmonary hypertension , Immunologic factors , Hypoxia , Cardiopulmonary development , Cell signaling
03 : 15 PM
Tet Methylcytosine Dioxygenase 2 mutation drives a global hypermethylation signature in patients with pulmonary arterial hypertension resulting in a common T cell phenotype.
Hindmarch Charles, Potus Francois, Al-qazazi Ruaa, Nichols William, Pauciulo Michael, Rauh Michael, Archer Stephen
Final Pr. ID: Su4177
Authors: Hindmarch Charles, Potus Francois, Al-qazazi Ruaa, Nichols William, Pauciulo Michael, Rauh Michael, Archer Stephen
Keywords: Epigenetics , Metabolism
03 : 15 PM
Opposing Responses to Oxygen in the Rabbit Ductus Arteriosus and Fetal Pulmonary Arteries: Proteomic Analysis Reveals Significant Metabolic Differences
Bentley Rachel, Prins Kurt, Martin Ashley, Emon Isaac, Hindmarch Charles, Archer Stephen
Final Pr. ID: Su4178
Authors: Bentley Rachel, Prins Kurt, Martin Ashley, Emon Isaac, Hindmarch Charles, Archer Stephen
Keywords: Proteomics , Pulmonary artery , Hypoxia , Mitochondria , Ductus arteriosus
03 : 15 PM
CCN2 Correlates with Early Markers of Right Ventricular Dysfunction in Adults with Pulmonary Arterial Hypertension
Schramm Jennifer, Byrd Carly, Ambade Anjira, Rosen Darin, Cubero Salazar Ilton, Simpson Catherine, Tedford Ryan, Hsu Steven, Hassoun Paul, Everett Allen, Damico Rachel
Final Pr. ID: Su4176
Authors: Schramm Jennifer, Byrd Carly, Ambade Anjira, Rosen Darin, Cubero Salazar Ilton, Simpson Catherine, Tedford Ryan, Hsu Steven, Hassoun Paul, Everett Allen, Damico Rachel
Keywords: Proteins , Right Ventricular Dysfunction
03 : 15 PM
Biased Activation of RXFP1 signaling via ML290 Attenuates Experimental Pulmonary Hypertension
Sangam Shreya, Triantafyllou Georgios, Pham Uyen, Troncone Luca, Yung Lai-ming, Chundi Anand, Darbha Srikrishna, Gipson Gregory, Rajesh Shreyas, Brackin Riley, Zeghibe Ana, Shin Elizabeth, Agoulnik Irina, Marugan Juan, Agoulnik Alexander, Rajagopal Sudarshan, Yu Paul
Final Pr. ID: Su4182
Authors: Sangam Shreya, Triantafyllou Georgios, Pham Uyen, Troncone Luca, Yung Lai-ming, Chundi Anand, Darbha Srikrishna, Gipson Gregory, Rajesh Shreyas, Brackin Riley, Zeghibe Ana, Shin Elizabeth, Agoulnik Irina, Marugan Juan, Agoulnik Alexander, Rajagopal Sudarshan, Yu Paul
Keywords: Pulmonary hypertension , Smooth muscle
03 : 15 PM
The role of colony-stimulating factor 1 receptor and perivascular macrophages in pulmonary arterial hypertension
Nishiura Kazuto, Yokokawa Tetsuro, Miura Shunsuke, Sato Akihiko, Shimizu Takeshi, Misaka Tomofumi, Oikawa Masayoshi, Yoshihisa Akiomi, Sugimoto Koichi, Nakazato Kazuhiko, Ishida Takafumi, Takeishi Yasuchika
Final Pr. ID: Su4174
Authors: Nishiura Kazuto, Yokokawa Tetsuro, Miura Shunsuke, Sato Akihiko, Shimizu Takeshi, Misaka Tomofumi, Oikawa Masayoshi, Yoshihisa Akiomi, Sugimoto Koichi, Nakazato Kazuhiko, Ishida Takafumi, Takeishi Yasuchika
Keywords: Pulmonary hypertension , Pulmonary artery
03 : 15 PM
Identification of ARMCX3 as potential mitochondria-related biomarker for pulmonary arterial hypertension using integrated bioinformatics analysis and machine learning
Zhang Zeying, Liu Qiming
Final Pr. ID: Su4180
Authors: Zhang Zeying, Liu Qiming
Keywords: Pulmonary hypertension
03 : 15 PM
Role of Inflammatory Cytokines in Triggering Ventricular Arrhythmias in Pulmonary Hypertension
Bronk Peter, Zhang Peng, Wang Eric, Radice Glenn, Tran Cao, Choudhary Gaurav, Choi Bum-rak
Final Pr. ID: Su4179
Authors: Bronk Peter, Zhang Peng, Wang Eric, Radice Glenn, Tran Cao, Choudhary Gaurav, Choi Bum-rak
Keywords: Ventricular arrhythmia , Pulmonary hypertension , Inflammation , Right Ventricular
03 : 15 PM
Mapping 3’ untranslated regions reveal compromised alternative polyadenylation in human right ventricle failure
Thandavarayan Rajarajan, Neupane Rahul, Mahalingam Rajasekaran, Suarez Erik, Wagner Eric, Yalamanchili Hari Krishna, Guha Ashrith
Final Pr. ID: Su4183
Authors: Thandavarayan Rajarajan, Neupane Rahul, Mahalingam Rajasekaran, Suarez Erik, Wagner Eric, Yalamanchili Hari Krishna, Guha Ashrith
Keywords: Right Ventricular Dysfunction , Gene expression
03 : 15 PM
Biased Activation of RXFP1 signaling via ML290 Attenuates Experimental Pulmonary Hypertension
Sangam Shreya, Triantafyllou Georgios, Pham Uyen, Troncone Luca, Yung Lai-ming, Chundi Anand, Darbha Srikrishna, Gipson Gregory, Rajesh Shreyas, Brackin Riley, Zeghibe Ana, Shin Elizabeth, Agoulnik Irina, Marugan Juan, Agoulnik Alexander, Rajagopal Sudarshan, Yu Paul
Final Pr. ID: Su4182
Authors: Sangam Shreya, Triantafyllou Georgios, Pham Uyen, Troncone Luca, Yung Lai-ming, Chundi Anand, Darbha Srikrishna, Gipson Gregory, Rajesh Shreyas, Brackin Riley, Zeghibe Ana, Shin Elizabeth, Agoulnik Irina, Marugan Juan, Agoulnik Alexander, Rajagopal Sudarshan, Yu Paul
Keywords: Pulmonary hypertension , Smooth muscle
03 : 15 PM
CCN2 Correlates with Early Markers of Right Ventricular Dysfunction in Adults with Pulmonary Arterial Hypertension
Schramm Jennifer, Byrd Carly, Ambade Anjira, Rosen Darin, Cubero Salazar Ilton, Simpson Catherine, Tedford Ryan, Hsu Steven, Hassoun Paul, Everett Allen, Damico Rachel
Final Pr. ID: Su4176
Authors: Schramm Jennifer, Byrd Carly, Ambade Anjira, Rosen Darin, Cubero Salazar Ilton, Simpson Catherine, Tedford Ryan, Hsu Steven, Hassoun Paul, Everett Allen, Damico Rachel
Keywords: Proteins , Right Ventricular Dysfunction
03 : 15 PM
Identification of ARMCX3 as potential mitochondria-related biomarker for pulmonary arterial hypertension using integrated bioinformatics analysis and machine learning
Zhang Zeying, Liu Qiming
Final Pr. ID: Su4180
Authors: Zhang Zeying, Liu Qiming
Keywords: Pulmonary hypertension
03 : 15 PM
Mapping 3’ untranslated regions reveal compromised alternative polyadenylation in human right ventricle failure
Thandavarayan Rajarajan, Neupane Rahul, Mahalingam Rajasekaran, Suarez Erik, Wagner Eric, Yalamanchili Hari Krishna, Guha Ashrith
Final Pr. ID: Su4183
Authors: Thandavarayan Rajarajan, Neupane Rahul, Mahalingam Rajasekaran, Suarez Erik, Wagner Eric, Yalamanchili Hari Krishna, Guha Ashrith
Keywords: Right Ventricular Dysfunction , Gene expression
03 : 15 PM
MHCIIhiLYVE1loCCR2hi Interstitial Macrophages Promote Medial Fibrosis in Pulmonary Arterioles and Contribute to Pulmonary Hypertension
Qiu Fan, Miao Hao-ran, Hui Hong-liang, Yangui Lin, Li Hua-ming, Li Dan, Luo Min, Ong Sang-bing, Hu Xue-fei, Jiang Bo, Zhang Yi-qian
Final Pr. ID: Su4175
Authors: Qiu Fan, Miao Hao-ran, Hui Hong-liang, Yangui Lin, Li Hua-ming, Li Dan, Luo Min, Ong Sang-bing, Hu Xue-fei, Jiang Bo, Zhang Yi-qian
Keywords: Pulmonary hypertension , Pulmonary vascular biology , Inflammation and inflammatory markers
03 : 15 PM
Opposing Responses to Oxygen in the Rabbit Ductus Arteriosus and Fetal Pulmonary Arteries: Proteomic Analysis Reveals Significant Metabolic Differences
Bentley Rachel, Prins Kurt, Martin Ashley, Emon Isaac, Hindmarch Charles, Archer Stephen
Final Pr. ID: Su4178
Authors: Bentley Rachel, Prins Kurt, Martin Ashley, Emon Isaac, Hindmarch Charles, Archer Stephen
Keywords: Proteomics , Pulmonary artery , Hypoxia , Mitochondria , Ductus arteriosus
03 : 15 PM
Role of Inflammatory Cytokines in Triggering Ventricular Arrhythmias in Pulmonary Hypertension
Bronk Peter, Zhang Peng, Wang Eric, Radice Glenn, Tran Cao, Choudhary Gaurav, Choi Bum-rak
Final Pr. ID: Su4179
Authors: Bronk Peter, Zhang Peng, Wang Eric, Radice Glenn, Tran Cao, Choudhary Gaurav, Choi Bum-rak
Keywords: Ventricular arrhythmia , Pulmonary hypertension , Inflammation , Right Ventricular
03 : 15 PM
Tet Methylcytosine Dioxygenase 2 mutation drives a global hypermethylation signature in patients with pulmonary arterial hypertension resulting in a common T cell phenotype.
Hindmarch Charles, Potus Francois, Al-qazazi Ruaa, Nichols William, Pauciulo Michael, Rauh Michael, Archer Stephen
Final Pr. ID: Su4177
Authors: Hindmarch Charles, Potus Francois, Al-qazazi Ruaa, Nichols William, Pauciulo Michael, Rauh Michael, Archer Stephen
Keywords: Epigenetics , Metabolism
03 : 15 PM
The critical role of CD206+ pro-PAH macrophages in contributing to severe pulmonary arterial hypertension and obliterative vascular remodeling
Dai Jingbo
Final Pr. ID: Su4181
Authors: Dai Jingbo
Keywords: Pulmonary hypertension , Immunologic factors , Hypoxia , Cardiopulmonary development , Cell signaling
03 : 15 PM
The role of colony-stimulating factor 1 receptor and perivascular macrophages in pulmonary arterial hypertension
Nishiura Kazuto, Yokokawa Tetsuro, Miura Shunsuke, Sato Akihiko, Shimizu Takeshi, Misaka Tomofumi, Oikawa Masayoshi, Yoshihisa Akiomi, Sugimoto Koichi, Nakazato Kazuhiko, Ishida Takafumi, Takeishi Yasuchika
Final Pr. ID: Su4174
Authors: Nishiura Kazuto, Yokokawa Tetsuro, Miura Shunsuke, Sato Akihiko, Shimizu Takeshi, Misaka Tomofumi, Oikawa Masayoshi, Yoshihisa Akiomi, Sugimoto Koichi, Nakazato Kazuhiko, Ishida Takafumi, Takeishi Yasuchika
Keywords: Pulmonary hypertension , Pulmonary artery