American Heart Association
Featured Science: Amyloid, Hypertrophic, and Danon Cardiomyopathies: Targeted Therapies and Specific Populations
Featured Science
S103BC
Nov 18th , 09:45 AM - 11:00 AM
09 : 45 AM
Danon Disease Phase 1 RP-A501 Results: The First Single-Dose Intravenous Gene Therapy with Recombinant Adeno-Associated Virus (AAV9:LAMP2B) for a Monogenic Cardiomyopathy
Greenberg Barry, Coggins Matthew, Schwartz Jonathan, Rossano Joseph, Taylor Matthew, Colan Steven, Adler Eric, Ricks David, Yarabe Paul, Battiprolu Pavan, Shah Guarav, Patel Kinnari
Final Pr. ID: 4168378
Authors: Greenberg Barry, Coggins Matthew, Schwartz Jonathan, Rossano Joseph, Taylor Matthew, Colan Steven, Adler Eric, Ricks David, Yarabe Paul, Battiprolu Pavan, Shah Guarav, Patel Kinnari
Keywords: Gene therapy , Hypertrophic cardiomyopathy , Clinical trials , Outcomes , Cardiomyopathy
Gillmore Julian, Taylor Matthew, Adler Eric
Final Pr. ID: -
Authors: Gillmore Julian, Taylor Matthew, Adler Eric
09 : 57 AM
Mavacamten Treatment in Patients with Obstructive HCM Referred for Septal Reduction Therapy: 128-Week Results from VALOR-HCM Trial
Desai Milind, Nissen Steven
Final Pr. ID: 4169095
Authors: Desai Milind, Nissen Steven
Keywords: Hypertrophic cardiomyopathy , Echocardiography
Deswal Anita, Ho Jennifer, Ho Carolyn, Day Sharlene
Final Pr. ID: -
Authors: Deswal Anita, Ho Jennifer, Ho Carolyn, Day Sharlene
10 : 09 AM
Acoramidis Reduces All-Cause Mortality (ACM) and Cardiovascular-Related Hospitalization (CVH): Initial Outcomes From the ATTRibute-CM Open-Label Extension (OLE) Study
Judge Daniel, Masri Ahmad, Obici Laura, Poulsen Steen, Sarswat Nitasha, Shah Keyur, Soman Prem, Cao Xiaofan, Wang Kevin, Pecoraro Maria, Tamby Jean-francois, Gillmore Julian, Katz Leonid, Fox Jonathan, Maurer Mathew, Alexander Kevin, Ambardekar Amrut, Cappelli Francesco, Fontana Marianna, Garcia-pavia Pablo, Grogan Martha, Hanna Mazen
Final Pr. ID: 4172052
Authors: Judge Daniel, Masri Ahmad, Obici Laura, Poulsen Steen, Sarswat Nitasha, Shah Keyur, Soman Prem, Cao Xiaofan, Wang Kevin, Pecoraro Maria, Tamby Jean-francois, Gillmore Julian, Katz Leonid, Fox Jonathan, Maurer Mathew, Alexander Kevin, Ambardekar Amrut, Cappelli Francesco, Fontana Marianna, Garcia-pavia Pablo, Grogan Martha, Hanna Mazen
Keywords: Amyloidosis , Clinical trials , Mortality , Heart failure , adult
10 : 17 AM
Impact of vutrisiran on outpatient worsening heart failure in patients with transthyretin amyloidosis with cardiomyopathy in the HELIOS-B trial
Fontana Marianna, Maurer Mathew, Gillmore Julian, Bender Shaun, Aldinc Emre, Eraly Satish, Jay Patrick, Solomon Scott
Final Pr. ID: 4171680
Authors: Fontana Marianna, Maurer Mathew, Gillmore Julian, Bender Shaun, Aldinc Emre, Eraly Satish, Jay Patrick, Solomon Scott
Keywords: Amyloidosis , Cardiomyopathy , Gene therapy , Interventional studies , Mortality
Grogan Martha, Kittleson Michelle, Nair Ajith, Grodin Justin, Ambardekar Amrut
Final Pr. ID: -
Authors: Grogan Martha, Kittleson Michelle, Nair Ajith, Grodin Justin, Ambardekar Amrut
10 : 33 AM
The prevalence of transthyretin cardiac amyloidosis in older Black and Hispanic individuals with heart failure: The Screening for Cardiac Amyloidosis with Nuclear imaging in Minority Populations Study
Ruberg Frederick, Blaner William, Deluca Albert, Johnson Lynne, Kinkhabwala Mona, Leb Jay, Mintz Akiva, Lavalley Michael, Einstein Andrew, Cohn Elizabeth, Kelly Jeffery, Teruya Sergio, Miller Edward, Maurer Mathew, Helmke Stephen, Fine Denise, Kurian Damian, Raiszadeh Farbod, Connors Lawreen, Prokaeva Tatiana, Pandey Shivda
Final Pr. ID: 4166799
Authors: Ruberg Frederick, Blaner William, Deluca Albert, Johnson Lynne, Kinkhabwala Mona, Leb Jay, Mintz Akiva, Lavalley Michael, Einstein Andrew, Cohn Elizabeth, Kelly Jeffery, Teruya Sergio, Miller Edward, Maurer Mathew, Helmke Stephen, Fine Denise, Kurian Damian, Raiszadeh Farbod, Connors Lawreen, Prokaeva Tatiana, Pandey Shivda
Keywords: Amyloidosis , Genetics , Cardiomyopathy , Aging
Alexander Kevin
Final Pr. ID: -
Authors: Alexander Kevin
10 : 45 AM
ATTR-Specific Medication in Dual Pathology Aortic Stenosis and Transthyretin Cardiac Amyloidosis.
Nitsche Christian, Muller Steven, Gama Francisco, Hamdan Ashraf, Kelion Andrew, Schuster Andreas, Glaveckaite Sigita, Porcari Aldostefano, Autherith Maximilian, Hauptmann Laurenz, Halavina Kseniya, Dobner Stephan, Scully Paul, Moon James, Mascherbauer Julia, Biagini Elena, Stortecky Stefan, Maurer Matthew, Treibel Thomas, Rosenblum Hannah, Patel Kush, Longhi Simone, Yilmaz Ali, Merlo Marco, Papathanasiou Maria, Griffin Jan
Final Pr. ID: 4169221
Authors: Nitsche Christian, Muller Steven, Gama Francisco, Hamdan Ashraf, Kelion Andrew, Schuster Andreas, Glaveckaite Sigita, Porcari Aldostefano, Autherith Maximilian, Hauptmann Laurenz, Halavina Kseniya, Dobner Stephan, Scully Paul, Moon James, Mascherbauer Julia, Biagini Elena, Stortecky Stefan, Maurer Matthew, Treibel Thomas, Rosenblum Hannah, Patel Kush, Longhi Simone, Yilmaz Ali, Merlo Marco, Papathanasiou Maria, Griffin Jan
Keywords: Amyloidosis , Aortic stenosis , TAVI/TAVR , Mortality , Heart failure
10 : 53 AM
Discussant: ATTR-Specific Medication in Dual Pathology Aortic Stenosis and Transthyretin Cardiac Amyloidosis
Nativi-nicolau Jose
Final Pr. ID: -
Authors: Nativi-nicolau Jose
10 : 09 AM
Acoramidis Reduces All-Cause Mortality (ACM) and Cardiovascular-Related Hospitalization (CVH): Initial Outcomes From the ATTRibute-CM Open-Label Extension (OLE) Study
Judge Daniel, Masri Ahmad, Obici Laura, Poulsen Steen, Sarswat Nitasha, Shah Keyur, Soman Prem, Cao Xiaofan, Wang Kevin, Pecoraro Maria, Tamby Jean-francois, Gillmore Julian, Katz Leonid, Fox Jonathan, Maurer Mathew, Alexander Kevin, Ambardekar Amrut, Cappelli Francesco, Fontana Marianna, Garcia-pavia Pablo, Grogan Martha, Hanna Mazen
Final Pr. ID: 4172052
Authors: Judge Daniel, Masri Ahmad, Obici Laura, Poulsen Steen, Sarswat Nitasha, Shah Keyur, Soman Prem, Cao Xiaofan, Wang Kevin, Pecoraro Maria, Tamby Jean-francois, Gillmore Julian, Katz Leonid, Fox Jonathan, Maurer Mathew, Alexander Kevin, Ambardekar Amrut, Cappelli Francesco, Fontana Marianna, Garcia-pavia Pablo, Grogan Martha, Hanna Mazen
Keywords: Amyloidosis , Clinical trials , Mortality , Heart failure , adult
10 : 45 AM
ATTR-Specific Medication in Dual Pathology Aortic Stenosis and Transthyretin Cardiac Amyloidosis.
Nitsche Christian, Muller Steven, Gama Francisco, Hamdan Ashraf, Kelion Andrew, Schuster Andreas, Glaveckaite Sigita, Porcari Aldostefano, Autherith Maximilian, Hauptmann Laurenz, Halavina Kseniya, Dobner Stephan, Scully Paul, Moon James, Mascherbauer Julia, Biagini Elena, Stortecky Stefan, Maurer Matthew, Treibel Thomas, Rosenblum Hannah, Patel Kush, Longhi Simone, Yilmaz Ali, Merlo Marco, Papathanasiou Maria, Griffin Jan
Final Pr. ID: 4169221
Authors: Nitsche Christian, Muller Steven, Gama Francisco, Hamdan Ashraf, Kelion Andrew, Schuster Andreas, Glaveckaite Sigita, Porcari Aldostefano, Autherith Maximilian, Hauptmann Laurenz, Halavina Kseniya, Dobner Stephan, Scully Paul, Moon James, Mascherbauer Julia, Biagini Elena, Stortecky Stefan, Maurer Matthew, Treibel Thomas, Rosenblum Hannah, Patel Kush, Longhi Simone, Yilmaz Ali, Merlo Marco, Papathanasiou Maria, Griffin Jan
Keywords: Amyloidosis , Aortic stenosis , TAVI/TAVR , Mortality , Heart failure
09 : 45 AM
Danon Disease Phase 1 RP-A501 Results: The First Single-Dose Intravenous Gene Therapy with Recombinant Adeno-Associated Virus (AAV9:LAMP2B) for a Monogenic Cardiomyopathy
Greenberg Barry, Coggins Matthew, Schwartz Jonathan, Rossano Joseph, Taylor Matthew, Colan Steven, Adler Eric, Ricks David, Yarabe Paul, Battiprolu Pavan, Shah Guarav, Patel Kinnari
Final Pr. ID: 4168378
Authors: Greenberg Barry, Coggins Matthew, Schwartz Jonathan, Rossano Joseph, Taylor Matthew, Colan Steven, Adler Eric, Ricks David, Yarabe Paul, Battiprolu Pavan, Shah Guarav, Patel Kinnari
Keywords: Gene therapy , Hypertrophic cardiomyopathy , Clinical trials , Outcomes , Cardiomyopathy
10 : 53 AM
Discussant: ATTR-Specific Medication in Dual Pathology Aortic Stenosis and Transthyretin Cardiac Amyloidosis
Nativi-nicolau Jose
Final Pr. ID: -
Authors: Nativi-nicolau Jose
Gillmore Julian, Taylor Matthew, Adler Eric
Final Pr. ID: -
Authors: Gillmore Julian, Taylor Matthew, Adler Eric
Grogan Martha, Kittleson Michelle, Nair Ajith, Grodin Justin, Ambardekar Amrut
Final Pr. ID: -
Authors: Grogan Martha, Kittleson Michelle, Nair Ajith, Grodin Justin, Ambardekar Amrut
Alexander Kevin
Final Pr. ID: -
Authors: Alexander Kevin
Deswal Anita, Ho Jennifer, Ho Carolyn, Day Sharlene
Final Pr. ID: -
Authors: Deswal Anita, Ho Jennifer, Ho Carolyn, Day Sharlene
10 : 17 AM
Impact of vutrisiran on outpatient worsening heart failure in patients with transthyretin amyloidosis with cardiomyopathy in the HELIOS-B trial
Fontana Marianna, Maurer Mathew, Gillmore Julian, Bender Shaun, Aldinc Emre, Eraly Satish, Jay Patrick, Solomon Scott
Final Pr. ID: 4171680
Authors: Fontana Marianna, Maurer Mathew, Gillmore Julian, Bender Shaun, Aldinc Emre, Eraly Satish, Jay Patrick, Solomon Scott
Keywords: Amyloidosis , Cardiomyopathy , Gene therapy , Interventional studies , Mortality
09 : 57 AM
Mavacamten Treatment in Patients with Obstructive HCM Referred for Septal Reduction Therapy: 128-Week Results from VALOR-HCM Trial
Desai Milind, Nissen Steven
Final Pr. ID: 4169095
Authors: Desai Milind, Nissen Steven
Keywords: Hypertrophic cardiomyopathy , Echocardiography
10 : 33 AM
The prevalence of transthyretin cardiac amyloidosis in older Black and Hispanic individuals with heart failure: The Screening for Cardiac Amyloidosis with Nuclear imaging in Minority Populations Study
Ruberg Frederick, Blaner William, Deluca Albert, Johnson Lynne, Kinkhabwala Mona, Leb Jay, Mintz Akiva, Lavalley Michael, Einstein Andrew, Cohn Elizabeth, Kelly Jeffery, Teruya Sergio, Miller Edward, Maurer Mathew, Helmke Stephen, Fine Denise, Kurian Damian, Raiszadeh Farbod, Connors Lawreen, Prokaeva Tatiana, Pandey Shivda
Final Pr. ID: 4166799
Authors: Ruberg Frederick, Blaner William, Deluca Albert, Johnson Lynne, Kinkhabwala Mona, Leb Jay, Mintz Akiva, Lavalley Michael, Einstein Andrew, Cohn Elizabeth, Kelly Jeffery, Teruya Sergio, Miller Edward, Maurer Mathew, Helmke Stephen, Fine Denise, Kurian Damian, Raiszadeh Farbod, Connors Lawreen, Prokaeva Tatiana, Pandey Shivda
Keywords: Amyloidosis , Genetics , Cardiomyopathy , Aging