American Heart Association
Novel Mechanistic and Therapeutic Insights Into Heart Failure
Moderated Digital Poster Session
Basic Science Zone, Moderated Digital Poster 26
Nov 9th , 11:50 AM - 12:50 PM
Flynn Spencer, Schuermans Art, Uddin Md Mesbah, Nakao Tetsushi, Viscosi Victoria, Libby Peter, Natarajan Pradeep, Honigberg Michael
Final Pr. ID: MP1861
Authors: Flynn Spencer, Schuermans Art, Uddin Md Mesbah, Nakao Tetsushi, Viscosi Victoria, Libby Peter, Natarajan Pradeep, Honigberg Michael
Keywords: Acute heart failure , Heart failure , adult , Gene mutations , Aging
11 : 57 AM
Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population
Enzan Nobuyuki, Miyazawa Kazuo, Koyama Satoshi, Kurosawa Ryo, Ieki Hirotaka, Takechi Fumie, Fukuyama Masashi, Osako Ryosuke, Tomizuka Kohei, Liu Xiaoxi, Ozaki Kouichi, Onouchi Yoshihiro, Matsuda Koichi, Momozawa Yukihide, Aburatani Hiroyuki, Kamatani Yoichiro, Yamaguchi Takanori, Akazawa Hiroshi, Node Koichi, Ellinor Patrick, Levin Michael, Damrauer Scott, Voight Benjamin, Joseph Jacob, Sun Yan, Terao Chikashi, Ninomiya Toshiharu, Komuro Issei, Ito Kaoru
Final Pr. ID: MP1862
Authors: Enzan Nobuyuki, Miyazawa Kazuo, Koyama Satoshi, Kurosawa Ryo, Ieki Hirotaka, Takechi Fumie, Fukuyama Masashi, Osako Ryosuke, Tomizuka Kohei, Liu Xiaoxi, Ozaki Kouichi, Onouchi Yoshihiro, Matsuda Koichi, Momozawa Yukihide, Aburatani Hiroyuki, Kamatani Yoichiro, Yamaguchi Takanori, Akazawa Hiroshi, Node Koichi, Ellinor Patrick, Levin Michael, Damrauer Scott, Voight Benjamin, Joseph Jacob, Sun Yan, Terao Chikashi, Ninomiya Toshiharu, Komuro Issei, Ito Kaoru
Keywords: Heart failure , Genome-wide association studies (GWAS) , Personalized Medicine , Prediction model , Genetics
12 : 04 PM
Machine Learning-Enabled Papillary Muscle Fibrosis Assessment in 51,000 Individuals Reveals Independent Links to Cardiac Structure, Function, and Disease and Identifies Genetic Susceptibility Loci
Nauffal Victor, Pace Danielle, Balasubramanian Aadhi, Kassir Jad, Danik Katherine, Friedman Sam, Simonson Bridget, Chilazi Michael, Maddah Mahnaz, Kwong Raymond, Ellinor Patrick
Final Pr. ID: MP1863
Authors: Nauffal Victor, Pace Danielle, Balasubramanian Aadhi, Kassir Jad, Danik Katherine, Friedman Sam, Simonson Bridget, Chilazi Michael, Maddah Mahnaz, Kwong Raymond, Ellinor Patrick
Keywords: Mitral valve disease , Genome-wide association studies (GWAS) , Machine Learning , Fibrosis , Magnetic resonance imaging
12 : 11 PM
TERRA Downregulation and Pathway Alterations in a Murine Model of Neurohormonal Heart Failure
Khraisat Sana'a, Brandt Moritz, Wenzel Philip
Final Pr. ID: MP1864
Authors: Khraisat Sana'a, Brandt Moritz, Wenzel Philip
Keywords: Aging , Heart failure , Angiotensin II , Gene expression
12 : 18 PM
Proof-of-Concept Viral Transduction in Human Living Myocardial Slices: Advancing Human Pre-Clinical Models for Cardiac Gene Therapy
Pamias Lopez Blanca, Pitoulis Fotios, Bedi Kenneth, Cheng Lan, Prosser Benjamin, Margulies Kenneth, Ibrahim Michael
Final Pr. ID: MP1865
Authors: Pamias Lopez Blanca, Pitoulis Fotios, Bedi Kenneth, Cheng Lan, Prosser Benjamin, Margulies Kenneth, Ibrahim Michael
Keywords: Gene therapy , Genetic techniques , Myocardial contraction
12 : 32 PM
Leveraging Single-Nucleus Chromatin Accessibility and Transcriptome Profiling to Define the Regulatory Landscape of Dilated Cardiomyopathy
Dunkenberger Logan, Gilles Casey, Belbachir Nadjet, Metzl Raz Eyal, Limbu Lasemahang, Bonham Spencer, Arthur Jennifer, Dalal Alex, Kay Maryam, Baum Rachel, Neofytou Evgenios, Ramchandani Rohin, Ameen Mo, Wang Kevin, Fischbein Michael, Woo Y Joseph, Karakikes Ioannis
Final Pr. ID: MP1867
Authors: Dunkenberger Logan, Gilles Casey, Belbachir Nadjet, Metzl Raz Eyal, Limbu Lasemahang, Bonham Spencer, Arthur Jennifer, Dalal Alex, Kay Maryam, Baum Rachel, Neofytou Evgenios, Ramchandani Rohin, Ameen Mo, Wang Kevin, Fischbein Michael, Woo Y Joseph, Karakikes Ioannis
Keywords: Cardiomyopathy , Transcriptomics , Epigenetics
12 : 39 PM
Two-Hit Model of JAK1–STAT1 Immune Amplification by Clonal Hematopoiesis in Immune Checkpoint Inhibitor-Associated Myocarditis
Manchanda Nancy, Jha Alokkumar, Kwan Jennifer
Final Pr. ID: MP1868
Authors: Manchanda Nancy, Jha Alokkumar, Kwan Jennifer
Keywords: Myocarditis , Cell signaling , Genomics , Transcriptomics , Immune system
Flynn Spencer, Schuermans Art, Uddin Md Mesbah, Nakao Tetsushi, Viscosi Victoria, Libby Peter, Natarajan Pradeep, Honigberg Michael
Final Pr. ID: MP1861
Authors: Flynn Spencer, Schuermans Art, Uddin Md Mesbah, Nakao Tetsushi, Viscosi Victoria, Libby Peter, Natarajan Pradeep, Honigberg Michael
Keywords: Acute heart failure , Heart failure , adult , Gene mutations , Aging
11 : 57 AM
Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population
Enzan Nobuyuki, Miyazawa Kazuo, Koyama Satoshi, Kurosawa Ryo, Ieki Hirotaka, Takechi Fumie, Fukuyama Masashi, Osako Ryosuke, Tomizuka Kohei, Liu Xiaoxi, Ozaki Kouichi, Onouchi Yoshihiro, Matsuda Koichi, Momozawa Yukihide, Aburatani Hiroyuki, Kamatani Yoichiro, Yamaguchi Takanori, Akazawa Hiroshi, Node Koichi, Ellinor Patrick, Levin Michael, Damrauer Scott, Voight Benjamin, Joseph Jacob, Sun Yan, Terao Chikashi, Ninomiya Toshiharu, Komuro Issei, Ito Kaoru
Final Pr. ID: MP1862
Authors: Enzan Nobuyuki, Miyazawa Kazuo, Koyama Satoshi, Kurosawa Ryo, Ieki Hirotaka, Takechi Fumie, Fukuyama Masashi, Osako Ryosuke, Tomizuka Kohei, Liu Xiaoxi, Ozaki Kouichi, Onouchi Yoshihiro, Matsuda Koichi, Momozawa Yukihide, Aburatani Hiroyuki, Kamatani Yoichiro, Yamaguchi Takanori, Akazawa Hiroshi, Node Koichi, Ellinor Patrick, Levin Michael, Damrauer Scott, Voight Benjamin, Joseph Jacob, Sun Yan, Terao Chikashi, Ninomiya Toshiharu, Komuro Issei, Ito Kaoru
Keywords: Heart failure , Genome-wide association studies (GWAS) , Personalized Medicine , Prediction model , Genetics
12 : 32 PM
Leveraging Single-Nucleus Chromatin Accessibility and Transcriptome Profiling to Define the Regulatory Landscape of Dilated Cardiomyopathy
Dunkenberger Logan, Gilles Casey, Belbachir Nadjet, Metzl Raz Eyal, Limbu Lasemahang, Bonham Spencer, Arthur Jennifer, Dalal Alex, Kay Maryam, Baum Rachel, Neofytou Evgenios, Ramchandani Rohin, Ameen Mo, Wang Kevin, Fischbein Michael, Woo Y Joseph, Karakikes Ioannis
Final Pr. ID: MP1867
Authors: Dunkenberger Logan, Gilles Casey, Belbachir Nadjet, Metzl Raz Eyal, Limbu Lasemahang, Bonham Spencer, Arthur Jennifer, Dalal Alex, Kay Maryam, Baum Rachel, Neofytou Evgenios, Ramchandani Rohin, Ameen Mo, Wang Kevin, Fischbein Michael, Woo Y Joseph, Karakikes Ioannis
Keywords: Cardiomyopathy , Transcriptomics , Epigenetics
12 : 04 PM
Machine Learning-Enabled Papillary Muscle Fibrosis Assessment in 51,000 Individuals Reveals Independent Links to Cardiac Structure, Function, and Disease and Identifies Genetic Susceptibility Loci
Nauffal Victor, Pace Danielle, Balasubramanian Aadhi, Kassir Jad, Danik Katherine, Friedman Sam, Simonson Bridget, Chilazi Michael, Maddah Mahnaz, Kwong Raymond, Ellinor Patrick
Final Pr. ID: MP1863
Authors: Nauffal Victor, Pace Danielle, Balasubramanian Aadhi, Kassir Jad, Danik Katherine, Friedman Sam, Simonson Bridget, Chilazi Michael, Maddah Mahnaz, Kwong Raymond, Ellinor Patrick
Keywords: Mitral valve disease , Genome-wide association studies (GWAS) , Machine Learning , Fibrosis , Magnetic resonance imaging
12 : 18 PM
Proof-of-Concept Viral Transduction in Human Living Myocardial Slices: Advancing Human Pre-Clinical Models for Cardiac Gene Therapy
Pamias Lopez Blanca, Pitoulis Fotios, Bedi Kenneth, Cheng Lan, Prosser Benjamin, Margulies Kenneth, Ibrahim Michael
Final Pr. ID: MP1865
Authors: Pamias Lopez Blanca, Pitoulis Fotios, Bedi Kenneth, Cheng Lan, Prosser Benjamin, Margulies Kenneth, Ibrahim Michael
Keywords: Gene therapy , Genetic techniques , Myocardial contraction
12 : 11 PM
TERRA Downregulation and Pathway Alterations in a Murine Model of Neurohormonal Heart Failure
Khraisat Sana'a, Brandt Moritz, Wenzel Philip
Final Pr. ID: MP1864
Authors: Khraisat Sana'a, Brandt Moritz, Wenzel Philip
Keywords: Aging , Heart failure , Angiotensin II , Gene expression
12 : 39 PM
Two-Hit Model of JAK1–STAT1 Immune Amplification by Clonal Hematopoiesis in Immune Checkpoint Inhibitor-Associated Myocarditis
Manchanda Nancy, Jha Alokkumar, Kwan Jennifer
Final Pr. ID: MP1868
Authors: Manchanda Nancy, Jha Alokkumar, Kwan Jennifer
Keywords: Myocarditis , Cell signaling , Genomics , Transcriptomics , Immune system