American Heart Association
Novel Cellular Stress Sensors in Cardiovascular Pathology: Metabolic, Mechanical, and Immune Interactions
Abstract Poster Board Session
Basic Science Zone
Nov 8th , 10:30 AM - 11:30 AM
Door Michaela, Stachowski Marisa, Sun Yan, Sherer Laura, Kontaridis Maria, Kirk Jonathan
Final Pr. ID: Sa4060
Authors: Door Michaela, Stachowski Marisa, Sun Yan, Sherer Laura, Kontaridis Maria, Kirk Jonathan
Keywords: HFpEF , Myofilaments , Sarcomere , Calcium , Cardiovascular disease
Yoder Micah, Papadaki Maria, Kelly Evan, Zied Ahmed, Markle Brandon, Muller Grace, Minh David, Kirk Jonathan
Final Pr. ID: Sa4061
Authors: Yoder Micah, Papadaki Maria, Kelly Evan, Zied Ahmed, Markle Brandon, Muller Grace, Minh David, Kirk Jonathan
Keywords: Cardiology , Contractility , Cell signaling , Arrhythmias
10 : 30 AM
Sex-Dependent Regulation of CYP2E1 Correlates with Changes in Energy Homeostasis in Mice Deficient for GDF15 in Brown Adipose Tissue
Jena Jayashree, Sood Ayushi, Peterson Joshua, Weatherford Eric, Patel Pritesh, Seeley Randy, Pereira Alambert Renata
Final Pr. ID: Sa4062
Authors: Jena Jayashree, Sood Ayushi, Peterson Joshua, Weatherford Eric, Patel Pritesh, Seeley Randy, Pereira Alambert Renata
Keywords: Sex differences , Adipose , Adipokine , Diabetes (Type II) , Hyperlipidemia
10 : 30 AM
Selective Degradation of NIMA-related kinase 7 (NEK7) via a Molecular Glue Degrader Inhibits IL-1 Downstream of NLRP3 Inflammasome Activation: A Novel Therapeutic Approach for Cardiovascular Inflammation
Wible Daric, Trouilloud Alexandra, Rush Kelsey, Strande Vaik, Bonenfant Debora, King Chris, Meier Kris, Cabanski Maciej, Kostikova Anna, Mcallister Laura, Janku Filip, Komishane Coleman, Walter Magnus, Liardo Elisa, Paterson Alison, Krishnan Eswar, Iracheta-vellve Arvin, Verdine Vanessa, Chen Qian, Chao Hoson, Nguyen Sophia, Schillo Martin, D'alessandro Anne Cecile, Gosala Keerthana
Final Pr. ID: Sa4063
Authors: Wible Daric, Trouilloud Alexandra, Rush Kelsey, Strande Vaik, Bonenfant Debora, King Chris, Meier Kris, Cabanski Maciej, Kostikova Anna, Mcallister Laura, Janku Filip, Komishane Coleman, Walter Magnus, Liardo Elisa, Paterson Alison, Krishnan Eswar, Iracheta-vellve Arvin, Verdine Vanessa, Chen Qian, Chao Hoson, Nguyen Sophia, Schillo Martin, D'alessandro Anne Cecile, Gosala Keerthana
Keywords: Inflammation , Inflammation and inflammatory markers , Immunology , Cardiovascular disease , Proteasome
Kang Ji-young, Mun Dasom, Park Malgeum, Yoo Gyeongseo, Joung Boyoung
Final Pr. ID: Sa4064
Authors: Kang Ji-young, Mun Dasom, Park Malgeum, Yoo Gyeongseo, Joung Boyoung
Keywords: Heart failure , Inflammation
10 : 30 AM
Differential changes in Atrial vs. Ventricular excitation-contraction coupling in transgenic mice expressing an autosomal dominant mutation in the human αB-crystallin gene (hR120GCryAB)
Aistrup Gary, Goodrow Robert, Xu Bing, Sunny Sini, Benjamin Ivor, Kontaridis Maria, Namakkal-soorappan Rajasekaran
Final Pr. ID: Sa4065
Authors: Aistrup Gary, Goodrow Robert, Xu Bing, Sunny Sini, Benjamin Ivor, Kontaridis Maria, Namakkal-soorappan Rajasekaran
Keywords: Myocyte electrophysiology , Calcium , Cardiomyopathy , Cell signaling , Gene mutations
10 : 30 AM
Matrix Stiffness Drives Myofibroblast Differentiation through Pyruvate Kinase M2 Regulated Metabolic Rewiring
Che Pulin, Zhang Xu, Wang Yuan
Final Pr. ID: Sa4066
Authors: Che Pulin, Zhang Xu, Wang Yuan
Keywords: Remodeling , Mitochondria , Extracellular matrix , Fibrosis , Metabolism
10 : 30 AM
The Inflammasome and Fibroblast Activation Protein in Heart Failure with Reduced Ejection Fraction
Mattia Victoria, Cavalli Eliana, Shazly Tarek, Thorn Stephanie, Sinusas Albert, Goldsmith Edie, Spinale Francis, Churillo Amelia, Freeburg Lisa, Maclaren Janna, Samani Stephanie, Delgra Vivian, Hofacre Courtney, Barlow Shayne, Jones Traci
Final Pr. ID: Sa4067
Authors: Mattia Victoria, Cavalli Eliana, Shazly Tarek, Thorn Stephanie, Sinusas Albert, Goldsmith Edie, Spinale Francis, Churillo Amelia, Freeburg Lisa, Maclaren Janna, Samani Stephanie, Delgra Vivian, Hofacre Courtney, Barlow Shayne, Jones Traci
Keywords: HFrEF , Molecular , Inflammation and inflammatory markers , Ischemia reperfusion , Fibrosis
10 : 30 AM
The Inflammasome and Fibroblast Transdifferentiation and Activation in Heart Failure with Reduced Ejection Fraction
Delgra Vivian, Shazly Tarek, Goldsmith Edie, Spinale Francis, Mattia Victoria, Churillo Amelia, Freeburg Lisa, Maclaren Janna, Samani Stephanie, Barlow Shayne, Jones Traci, Cavalli Eliana
Final Pr. ID: Sa4068
Authors: Delgra Vivian, Shazly Tarek, Goldsmith Edie, Spinale Francis, Mattia Victoria, Churillo Amelia, Freeburg Lisa, Maclaren Janna, Samani Stephanie, Barlow Shayne, Jones Traci, Cavalli Eliana
Keywords: HFrEF , Ischemia reperfusion , Myocardial infarction , Cells , Fibrosis
10 : 30 AM
RNS-Related Myocardial Injury: Sympathetic Activation-Induced Proinflammatory Bone Marrow Remodeling and Trained Immunity
Lin Yekai, Xia Yan, Chen Ao, Che Xinyu, Jing Shengyu, Lu Danbo, Ma Jiaqi, Qian Juying, Ge Junbo
Final Pr. ID: Sa4069
Authors: Lin Yekai, Xia Yan, Chen Ao, Che Xinyu, Jing Shengyu, Lu Danbo, Ma Jiaqi, Qian Juying, Ge Junbo
Keywords: Sleep Pattern , Epigenetics , Immunology , Cardiovascular Risk
10 : 30 AM
Differential changes in Atrial vs. Ventricular excitation-contraction coupling in transgenic mice expressing an autosomal dominant mutation in the human αB-crystallin gene (hR120GCryAB)
Aistrup Gary, Goodrow Robert, Xu Bing, Sunny Sini, Benjamin Ivor, Kontaridis Maria, Namakkal-soorappan Rajasekaran
Final Pr. ID: Sa4065
Authors: Aistrup Gary, Goodrow Robert, Xu Bing, Sunny Sini, Benjamin Ivor, Kontaridis Maria, Namakkal-soorappan Rajasekaran
Keywords: Myocyte electrophysiology , Calcium , Cardiomyopathy , Cell signaling , Gene mutations
Kang Ji-young, Mun Dasom, Park Malgeum, Yoo Gyeongseo, Joung Boyoung
Final Pr. ID: Sa4064
Authors: Kang Ji-young, Mun Dasom, Park Malgeum, Yoo Gyeongseo, Joung Boyoung
Keywords: Heart failure , Inflammation
10 : 30 AM
Matrix Stiffness Drives Myofibroblast Differentiation through Pyruvate Kinase M2 Regulated Metabolic Rewiring
Che Pulin, Zhang Xu, Wang Yuan
Final Pr. ID: Sa4066
Authors: Che Pulin, Zhang Xu, Wang Yuan
Keywords: Remodeling , Mitochondria , Extracellular matrix , Fibrosis , Metabolism
Door Michaela, Stachowski Marisa, Sun Yan, Sherer Laura, Kontaridis Maria, Kirk Jonathan
Final Pr. ID: Sa4060
Authors: Door Michaela, Stachowski Marisa, Sun Yan, Sherer Laura, Kontaridis Maria, Kirk Jonathan
Keywords: HFpEF , Myofilaments , Sarcomere , Calcium , Cardiovascular disease
10 : 30 AM
RNS-Related Myocardial Injury: Sympathetic Activation-Induced Proinflammatory Bone Marrow Remodeling and Trained Immunity
Lin Yekai, Xia Yan, Chen Ao, Che Xinyu, Jing Shengyu, Lu Danbo, Ma Jiaqi, Qian Juying, Ge Junbo
Final Pr. ID: Sa4069
Authors: Lin Yekai, Xia Yan, Chen Ao, Che Xinyu, Jing Shengyu, Lu Danbo, Ma Jiaqi, Qian Juying, Ge Junbo
Keywords: Sleep Pattern , Epigenetics , Immunology , Cardiovascular Risk
10 : 30 AM
Selective Degradation of NIMA-related kinase 7 (NEK7) via a Molecular Glue Degrader Inhibits IL-1 Downstream of NLRP3 Inflammasome Activation: A Novel Therapeutic Approach for Cardiovascular Inflammation
Wible Daric, Trouilloud Alexandra, Rush Kelsey, Strande Vaik, Bonenfant Debora, King Chris, Meier Kris, Cabanski Maciej, Kostikova Anna, Mcallister Laura, Janku Filip, Komishane Coleman, Walter Magnus, Liardo Elisa, Paterson Alison, Krishnan Eswar, Iracheta-vellve Arvin, Verdine Vanessa, Chen Qian, Chao Hoson, Nguyen Sophia, Schillo Martin, D'alessandro Anne Cecile, Gosala Keerthana
Final Pr. ID: Sa4063
Authors: Wible Daric, Trouilloud Alexandra, Rush Kelsey, Strande Vaik, Bonenfant Debora, King Chris, Meier Kris, Cabanski Maciej, Kostikova Anna, Mcallister Laura, Janku Filip, Komishane Coleman, Walter Magnus, Liardo Elisa, Paterson Alison, Krishnan Eswar, Iracheta-vellve Arvin, Verdine Vanessa, Chen Qian, Chao Hoson, Nguyen Sophia, Schillo Martin, D'alessandro Anne Cecile, Gosala Keerthana
Keywords: Inflammation , Inflammation and inflammatory markers , Immunology , Cardiovascular disease , Proteasome
10 : 30 AM
Sex-Dependent Regulation of CYP2E1 Correlates with Changes in Energy Homeostasis in Mice Deficient for GDF15 in Brown Adipose Tissue
Jena Jayashree, Sood Ayushi, Peterson Joshua, Weatherford Eric, Patel Pritesh, Seeley Randy, Pereira Alambert Renata
Final Pr. ID: Sa4062
Authors: Jena Jayashree, Sood Ayushi, Peterson Joshua, Weatherford Eric, Patel Pritesh, Seeley Randy, Pereira Alambert Renata
Keywords: Sex differences , Adipose , Adipokine , Diabetes (Type II) , Hyperlipidemia
Yoder Micah, Papadaki Maria, Kelly Evan, Zied Ahmed, Markle Brandon, Muller Grace, Minh David, Kirk Jonathan
Final Pr. ID: Sa4061
Authors: Yoder Micah, Papadaki Maria, Kelly Evan, Zied Ahmed, Markle Brandon, Muller Grace, Minh David, Kirk Jonathan
Keywords: Cardiology , Contractility , Cell signaling , Arrhythmias
10 : 30 AM
The Inflammasome and Fibroblast Activation Protein in Heart Failure with Reduced Ejection Fraction
Mattia Victoria, Cavalli Eliana, Shazly Tarek, Thorn Stephanie, Sinusas Albert, Goldsmith Edie, Spinale Francis, Churillo Amelia, Freeburg Lisa, Maclaren Janna, Samani Stephanie, Delgra Vivian, Hofacre Courtney, Barlow Shayne, Jones Traci
Final Pr. ID: Sa4067
Authors: Mattia Victoria, Cavalli Eliana, Shazly Tarek, Thorn Stephanie, Sinusas Albert, Goldsmith Edie, Spinale Francis, Churillo Amelia, Freeburg Lisa, Maclaren Janna, Samani Stephanie, Delgra Vivian, Hofacre Courtney, Barlow Shayne, Jones Traci
Keywords: HFrEF , Molecular , Inflammation and inflammatory markers , Ischemia reperfusion , Fibrosis
10 : 30 AM
The Inflammasome and Fibroblast Transdifferentiation and Activation in Heart Failure with Reduced Ejection Fraction
Delgra Vivian, Shazly Tarek, Goldsmith Edie, Spinale Francis, Mattia Victoria, Churillo Amelia, Freeburg Lisa, Maclaren Janna, Samani Stephanie, Barlow Shayne, Jones Traci, Cavalli Eliana
Final Pr. ID: Sa4068
Authors: Delgra Vivian, Shazly Tarek, Goldsmith Edie, Spinale Francis, Mattia Victoria, Churillo Amelia, Freeburg Lisa, Maclaren Janna, Samani Stephanie, Barlow Shayne, Jones Traci, Cavalli Eliana
Keywords: HFrEF , Ischemia reperfusion , Myocardial infarction , Cells , Fibrosis