Showing 6 Abstracts.
04 : 30 PM
Acute Administration of The Novel Cardiac Sarcomere Modulator EDG-7500, Improves Ventricular Filling While Preserving LVEF In Dogs with Pacing Induced Left-Ventricular Systolic Dysfunction
Evanchik Marc, Emter Craig, Del Rio Carlos, Roof Steve, St Clair Sydney, Russell Alan, Henze Marcus, Semigran Marc
Final Pr. ID: We094
Authors: Evanchik Marc , Emter Craig , Del Rio Carlos , Roof Steve , St Clair Sydney , Russell Alan , Henze Marcus , Semigran Marc
Keywords: Cardiovascular therapeutics, Diastolic function, HFpEF, HFrEF, Cardiomyopathy
04 : 30 PM
CD36-Mediated Transendothelial Fatty Acid Transport Determines Cardiomyocyte Uptake and is Critical to Limiting a Lipotoxic Ceramide Profile and Supporting Cardiac Function during Pathological Stress.
Challa Azariyas, Carley Andrew, Maurya Chandan Kumar, Wang Yang, Fasano Matthew, Goldberg Ira, Lewandowski E Douglas
Final Pr. ID: Tu110
Authors: Challa Azariyas , Carley Andrew , Maurya Chandan Kumar , Wang Yang , Fasano Matthew , Goldberg Ira , Lewandowski E Douglas
Keywords: Cardiac metabolism, HFrEF, Energy metabolism, Endothelial function
04 : 30 PM
Endothelial Cell STING contributes to Systolic Dysfunction by modulating cardiomyocyte hypertrophy and capillary density in pressure overload-induced heart failure
Sanders Erin, Wagner Noah, Bayer Abraham, Smolgovsky Sasha, Theall Brandon, Aronovitz Mark, Blanton Robert, Kaur Kuljeet, Alcaide Pilar
Final Pr. ID: Tu084
Authors: Sanders Erin , Wagner Noah , Bayer Abraham , Smolgovsky Sasha , Theall Brandon , Aronovitz Mark , Blanton Robert , Kaur Kuljeet , Alcaide Pilar
Keywords: Endothelium, Cardiac hypertrophy, HFrEF
Martin Thomas, Hunt Dakota, Ebmeier Christopher, Ambardekar Amrut, Buttrick Peter, Leinwand Leslie
Final Pr. ID: Tu058
Authors: Martin Thomas , Hunt Dakota , Ebmeier Christopher , Ambardekar Amrut , Buttrick Peter , Leinwand Leslie
Keywords: HFrEF, Cardiac hypertrophy, Cardiac rehabilitation, Device, Molecular biology
04 : 30 PM
RPN6-Serine14 Phosphorylation by PKA Protects Against Systolic Overload-Induced Cardiac Remodeling and Heart Failure
Ahammed Md Salim, Wu Penglong, Yang Liuqing, Sternburg Jack, Liang Huiyun, Li Faqian, Liu Jin, Wang Xuejun
Final Pr. ID: Tu052
Authors: Ahammed Md Salim , Wu Penglong , Yang Liuqing , Sternburg Jack , Liang Huiyun , Li Faqian , Liu Jin , Wang Xuejun
Keywords: Proteasome, Heart failure, HFrEF, Fibrosis
09 : 51 AM
Targeting Tropomyosin Overlap Flexibility via Small Molecule Intervention in a Murine Dilated Cardiomyopathy Model
Vasquez Catherine, Lynn Melissa, Tardiff Jil
Final Pr. ID: Or104
Authors: Vasquez Catherine , Lynn Melissa , Tardiff Jil
Keywords: Cardiomyopathy, HFrEF