American Heart Association
Electropathogenesis: Cellular Mechanisms Driving Arrhythmogenic Cardiomyopathies
Moderated Digital Poster Session
Basic Science Zone, Moderated Digital Poster 25
Nov 8th , 09:15 AM - 10:30 AM
09 : 15 AM
Cell Painting Based High-Content Phenotypic Screening To Elucidate Kinase Signaling Pathways in BTK-Inhibitor Mediated Atrial Fibrillation
Fleming Matthew, Diaz Verdugo Carmen, Egly Christian, Blair Marcia, Hasaka Thomas, Bauer Joshua, Knollmann Bjorn, Ellinor Patrick, Roden Dan
Final Pr. ID: MP1072
Authors: Fleming Matthew, Diaz Verdugo Carmen, Egly Christian, Blair Marcia, Hasaka Thomas, Bauer Joshua, Knollmann Bjorn, Ellinor Patrick, Roden Dan
Keywords: Cardio-oncology , Atrial fibrillation , Signal transduction , Cell signaling , Cell physiology
09 : 22 AM
Prokaryotic Voltage-Gated Sodium Channel (BacNav) Gene Therapy Restores Contractile and Electrical Function in a Rat Model of Chronic Ischemia-Reperfusion Heart Failure
Siu Yiu Yan, Li Yongwu, Tornatore Anna, Wertheimer Bianca, Bursac Nenad
Final Pr. ID: MP1073
Authors: Siu Yiu Yan, Li Yongwu, Tornatore Anna, Wertheimer Bianca, Bursac Nenad
Keywords: Myocardial infarction , Arrhythmias , treatment of , Gene therapy , Heart failure
09 : 29 AM
Adipose tissue extracellular vesicles mediate pro-arrhythmic changes in atrial cardiomyocytes
Limpitikul Worawan, Garcia Contreras Marta, Betti Michael, Sheng Quanhu, Xiao Ling, Chatterjee Emeli, Gamazon Eric, Shah Ravi, Das Saumya
Final Pr. ID: MP1074
Authors: Limpitikul Worawan, Garcia Contreras Marta, Betti Michael, Sheng Quanhu, Xiao Ling, Chatterjee Emeli, Gamazon Eric, Shah Ravi, Das Saumya
Keywords: Adipose , Cellular electrophysiology , Genome-wide association studies (GWAS) , Obesity , Atrial arrhythmias
09 : 36 AM
Trimethylamine N-oxide Promotes Atrial Arrhythmia Susceptibility via Neuroglial IL-1β-Driven Inflammatory Activation of the Left Stellate Ganglion
Cheng Hongyi, Xu Zhou, Zhang Yike, Zhu Yue, Chen Minglong, Cui Chang
Final Pr. ID: MP1075
Authors: Cheng Hongyi, Xu Zhou, Zhang Yike, Zhu Yue, Chen Minglong, Cui Chang
Keywords: Arrhythmias , Atrial fibrillation , Eating pattern , Inflammation , Neuroprotection
Torres Natalia, Kauffman Christopher, Yang Yueqin, Cho Scott, Tristani-firouzi Martin
Final Pr. ID: MP1076
Authors: Torres Natalia, Kauffman Christopher, Yang Yueqin, Cho Scott, Tristani-firouzi Martin
Keywords: Arrhythmias , Atrial fibrillation , Genomics , Electrophysiology , Cardiovascular disease
09 : 50 AM
Inflammation as a driver of arrhythmogenic cardiomyopathies; insights from the buccal epithelium
Jager Joanna, Bueno Beti Carlos, Field Ella, Luedke Leonie, Moscatelli Sara, Behr Elijah, Kaski Juan Pablo, Asimaki Angeliki
Final Pr. ID: MP1077
Authors: Jager Joanna, Bueno Beti Carlos, Field Ella, Luedke Leonie, Moscatelli Sara, Behr Elijah, Kaski Juan Pablo, Asimaki Angeliki
Keywords: Inflammation , Cardiovascular disease , Research , Sudden cardiac death
09 : 57 AM
Regulation of Nav1.5 Channel Surface Expression and Function by Sorbs2 in Atrial Cardiomyocytes
Ou Mengchan, Zou Tian, Sun Xiaojing, Lee Hon-chi, Lu Tong
Final Pr. ID: MP1078
Authors: Ou Mengchan, Zou Tian, Sun Xiaojing, Lee Hon-chi, Lu Tong
Keywords: Electrophysiology , Arrhythmias , Ion channels , Myocyte electrophysiology , Sodium channel
10 : 04 AM
Metabolic interventions modulate arrhythmogenic cardiomyopathy phenotype and severity in knock-in mice carrying Tmem43 S358L mutation.
Orgil Buyan-ochir, Alberson Neely, Johnson Jason, Baba Zainab, Black Dennis, Towbin Jeffrey, Pierre Joseph, Purevjav Enkhsaikhan
Final Pr. ID: MP1079
Authors: Orgil Buyan-ochir, Alberson Neely, Johnson Jason, Baba Zainab, Black Dennis, Towbin Jeffrey, Pierre Joseph, Purevjav Enkhsaikhan
Keywords: Cardiomyopathy , Cardiometabolic health
10 : 11 AM
Gαq-dependent signaling promotes atrial fibrillation through arrhythmogenic triggered calcium waves and inhomogeneous conduction in a canine heart failure model
Pfenniger Anna, Knight Bradley, Wasserstrom J, Arora Rishi, Bhatnagar Ashita, Glinton Kristofor, Johnson David, Zhang Wenwei, Mikhailov Aleksei, Ober Rebecca, Mcluckie Alicia, Burrell Amy
Final Pr. ID: MP1080
Authors: Pfenniger Anna, Knight Bradley, Wasserstrom J, Arora Rishi, Bhatnagar Ashita, Glinton Kristofor, Johnson David, Zhang Wenwei, Mikhailov Aleksei, Ober Rebecca, Mcluckie Alicia, Burrell Amy
Keywords: Atrial fibrillation , Heart failure , Calcium , Gene therapy , Arrhythmias
10 : 18 AM
DENND3-p.R534S Induces Electrophysiological Instability by Intracellular Calcium Mishandling in Cardiomyocytes
Gao Shan, Kim Changsung, Tester David, Giudicessi John, Ackerman Michael
Final Pr. ID: MP1081
Authors: Gao Shan, Kim Changsung, Tester David, Giudicessi John, Ackerman Michael
Keywords: Arrhythmias , Calcium , Gene mutations
09 : 29 AM
Adipose tissue extracellular vesicles mediate pro-arrhythmic changes in atrial cardiomyocytes
Limpitikul Worawan, Garcia Contreras Marta, Betti Michael, Sheng Quanhu, Xiao Ling, Chatterjee Emeli, Gamazon Eric, Shah Ravi, Das Saumya
Final Pr. ID: MP1074
Authors: Limpitikul Worawan, Garcia Contreras Marta, Betti Michael, Sheng Quanhu, Xiao Ling, Chatterjee Emeli, Gamazon Eric, Shah Ravi, Das Saumya
Keywords: Adipose , Cellular electrophysiology , Genome-wide association studies (GWAS) , Obesity , Atrial arrhythmias
09 : 15 AM
Cell Painting Based High-Content Phenotypic Screening To Elucidate Kinase Signaling Pathways in BTK-Inhibitor Mediated Atrial Fibrillation
Fleming Matthew, Diaz Verdugo Carmen, Egly Christian, Blair Marcia, Hasaka Thomas, Bauer Joshua, Knollmann Bjorn, Ellinor Patrick, Roden Dan
Final Pr. ID: MP1072
Authors: Fleming Matthew, Diaz Verdugo Carmen, Egly Christian, Blair Marcia, Hasaka Thomas, Bauer Joshua, Knollmann Bjorn, Ellinor Patrick, Roden Dan
Keywords: Cardio-oncology , Atrial fibrillation , Signal transduction , Cell signaling , Cell physiology
10 : 18 AM
DENND3-p.R534S Induces Electrophysiological Instability by Intracellular Calcium Mishandling in Cardiomyocytes
Gao Shan, Kim Changsung, Tester David, Giudicessi John, Ackerman Michael
Final Pr. ID: MP1081
Authors: Gao Shan, Kim Changsung, Tester David, Giudicessi John, Ackerman Michael
Keywords: Arrhythmias , Calcium , Gene mutations
10 : 11 AM
Gαq-dependent signaling promotes atrial fibrillation through arrhythmogenic triggered calcium waves and inhomogeneous conduction in a canine heart failure model
Pfenniger Anna, Knight Bradley, Wasserstrom J, Arora Rishi, Bhatnagar Ashita, Glinton Kristofor, Johnson David, Zhang Wenwei, Mikhailov Aleksei, Ober Rebecca, Mcluckie Alicia, Burrell Amy
Final Pr. ID: MP1080
Authors: Pfenniger Anna, Knight Bradley, Wasserstrom J, Arora Rishi, Bhatnagar Ashita, Glinton Kristofor, Johnson David, Zhang Wenwei, Mikhailov Aleksei, Ober Rebecca, Mcluckie Alicia, Burrell Amy
Keywords: Atrial fibrillation , Heart failure , Calcium , Gene therapy , Arrhythmias
09 : 50 AM
Inflammation as a driver of arrhythmogenic cardiomyopathies; insights from the buccal epithelium
Jager Joanna, Bueno Beti Carlos, Field Ella, Luedke Leonie, Moscatelli Sara, Behr Elijah, Kaski Juan Pablo, Asimaki Angeliki
Final Pr. ID: MP1077
Authors: Jager Joanna, Bueno Beti Carlos, Field Ella, Luedke Leonie, Moscatelli Sara, Behr Elijah, Kaski Juan Pablo, Asimaki Angeliki
Keywords: Inflammation , Cardiovascular disease , Research , Sudden cardiac death
10 : 04 AM
Metabolic interventions modulate arrhythmogenic cardiomyopathy phenotype and severity in knock-in mice carrying Tmem43 S358L mutation.
Orgil Buyan-ochir, Alberson Neely, Johnson Jason, Baba Zainab, Black Dennis, Towbin Jeffrey, Pierre Joseph, Purevjav Enkhsaikhan
Final Pr. ID: MP1079
Authors: Orgil Buyan-ochir, Alberson Neely, Johnson Jason, Baba Zainab, Black Dennis, Towbin Jeffrey, Pierre Joseph, Purevjav Enkhsaikhan
Keywords: Cardiomyopathy , Cardiometabolic health
09 : 22 AM
Prokaryotic Voltage-Gated Sodium Channel (BacNav) Gene Therapy Restores Contractile and Electrical Function in a Rat Model of Chronic Ischemia-Reperfusion Heart Failure
Siu Yiu Yan, Li Yongwu, Tornatore Anna, Wertheimer Bianca, Bursac Nenad
Final Pr. ID: MP1073
Authors: Siu Yiu Yan, Li Yongwu, Tornatore Anna, Wertheimer Bianca, Bursac Nenad
Keywords: Myocardial infarction , Arrhythmias , treatment of , Gene therapy , Heart failure
09 : 57 AM
Regulation of Nav1.5 Channel Surface Expression and Function by Sorbs2 in Atrial Cardiomyocytes
Ou Mengchan, Zou Tian, Sun Xiaojing, Lee Hon-chi, Lu Tong
Final Pr. ID: MP1078
Authors: Ou Mengchan, Zou Tian, Sun Xiaojing, Lee Hon-chi, Lu Tong
Keywords: Electrophysiology , Arrhythmias , Ion channels , Myocyte electrophysiology , Sodium channel
Torres Natalia, Kauffman Christopher, Yang Yueqin, Cho Scott, Tristani-firouzi Martin
Final Pr. ID: MP1076
Authors: Torres Natalia, Kauffman Christopher, Yang Yueqin, Cho Scott, Tristani-firouzi Martin
Keywords: Arrhythmias , Atrial fibrillation , Genomics , Electrophysiology , Cardiovascular disease
09 : 36 AM
Trimethylamine N-oxide Promotes Atrial Arrhythmia Susceptibility via Neuroglial IL-1β-Driven Inflammatory Activation of the Left Stellate Ganglion
Cheng Hongyi, Xu Zhou, Zhang Yike, Zhu Yue, Chen Minglong, Cui Chang
Final Pr. ID: MP1075
Authors: Cheng Hongyi, Xu Zhou, Zhang Yike, Zhu Yue, Chen Minglong, Cui Chang
Keywords: Arrhythmias , Atrial fibrillation , Eating pattern , Inflammation , Neuroprotection