American Heart Association
Going Solo: Insights From Single Cell, Single Molecule and Novel Molecular Analyses
Abstract Poster Session
Zone 4
Nov 16th , 10:30 AM - 11:30 AM
10 : 30 AM
Network Analysis of Differentially Expressed Genes after Silencing Dynamin 2 in Pulmonary Arterial Hypertension
Wu Danchen, Das Gupta Asish, Chen Kuang-hueih, Hindmarch Charles, Hu Ting, Archer Stephen
Final Pr. ID: Sa4119
Authors: Wu Danchen, Das Gupta Asish, Chen Kuang-hueih, Hindmarch Charles, Hu Ting, Archer Stephen
Keywords: Pulmonary hypertension , Mitochondria
Hong Jason, Wong Brenda, Brownstein Adam, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh
Final Pr. ID: Sa4116
Authors: Hong Jason, Wong Brenda, Brownstein Adam, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh
Keywords: Pulmonary hypertension , Pulmonary vascular biology , Transcriptomics
10 : 30 AM
eQTL Analysis of the PAH Biomarker CCN2 Identifies a Novel SNP that Associates with Survival
Byrd Carly, Simpson Catherine, Kolb Todd, Pauciulo Michael, Nichols William, Ivy Dunbar, Hassoun Paul, Everett Allen, Austin Eric, Martin Lisa, Benza Raymond, Webb Amy, Schramm Jennifer, Yang Jun, Griffiths Megan, Brandal Stephanie, Damico Rachel, Vaidya Dhananjay
Final Pr. ID: Sa4122
Authors: Byrd Carly, Simpson Catherine, Kolb Todd, Pauciulo Michael, Nichols William, Ivy Dunbar, Hassoun Paul, Everett Allen, Austin Eric, Martin Lisa, Benza Raymond, Webb Amy, Schramm Jennifer, Yang Jun, Griffiths Megan, Brandal Stephanie, Damico Rachel, Vaidya Dhananjay
Keywords: Pulmonary hypertension , Genetics , Genome-wide association studies (GWAS) , Biomarkers , Risk Factors
10 : 30 AM
Single Cell Transcriptomics Unveils Novel Lung Capillary Endothelial Cell Populations and Their Crucial Roles
James Joel, Dekan Aleksandr, Bharti Dinesh, Valuparampil Varghese Mathews, Kacar Sedat, Niihori Maki, Rafikova Olga, Rafikov Ruslan
Final Pr. ID: Sa4123
Authors: James Joel, Dekan Aleksandr, Bharti Dinesh, Valuparampil Varghese Mathews, Kacar Sedat, Niihori Maki, Rafikova Olga, Rafikov Ruslan
Keywords: Endothelial , Endothelial function , Vascular development , Pulmonary circulation , Arteries
10 : 30 AM
Individualized Interactomes from Pulmonary Arterial Hypertension Biopsies Predict Therapeutic Response: an In Silico Clinical Study
Wang Ruisheng, Harrington Elizabeth, Maron Brad, Ventetuolo Corey, Singh Navneet, Wathieu Henri, Baird Grayson, Cox-flaherty Katherine, Klinger James, Mullin Christopher, Pereira Mandy, Whittenhall Mary
Final Pr. ID: Sa4118
Authors: Wang Ruisheng, Harrington Elizabeth, Maron Brad, Ventetuolo Corey, Singh Navneet, Wathieu Henri, Baird Grayson, Cox-flaherty Katherine, Klinger James, Mullin Christopher, Pereira Mandy, Whittenhall Mary
Keywords: Pulmonary hypertension , Systems biology , Transcriptomics
Besse Casandra, Puerta Cristian, Winicki Nolan, Hernandez Moises, Thistlethwaite Patricia
Final Pr. ID: Sa4124
Authors: Besse Casandra, Puerta Cristian, Winicki Nolan, Hernandez Moises, Thistlethwaite Patricia
Keywords: Pulmonary hypertension , Clinical trials , Molecular biology
10 : 30 AM
Upregulation of Dynamin 2 (DNM2) Increases Mitochondrial Fission and Cell Proliferation in Pulmonary Arterial Hypertension
Das Gupta Asish, Yerramilli Siddartha, Jones Oliver, Hindmarch Charles, Potus Francois, Bonnet Sebastien, Archer Stephen, Chen Kuang-hueih, Wu Danchen, Lima Patricia, Martin Ashley, Mewburn Jeffrey, Al-qazazi Ruaa, Emon Isaac, Colpman Pierce
Final Pr. ID: Sa4120
Authors: Das Gupta Asish, Yerramilli Siddartha, Jones Oliver, Hindmarch Charles, Potus Francois, Bonnet Sebastien, Archer Stephen, Chen Kuang-hueih, Wu Danchen, Lima Patricia, Martin Ashley, Mewburn Jeffrey, Al-qazazi Ruaa, Emon Isaac, Colpman Pierce
Keywords: Pulmonary hypertension , Cell signaling , Cardiovascular , Cells , Cell physiology
10 : 30 AM
Non-canonical CDC20 signaling promotes smooth muscle and adventitial fibroblasts hyper-proliferation and remodeling in pulmonary arterial hypertension
Dey Tapan, Wolters Paul, Jiang Lifeng, Goncharova Elena, Goncharov Dmitry, Zhyvylo Iryna, Lin Derek, Shah Maanvi, Saiyed Aisha, Neeli Sanjana, Kudryashova Tatiana, Greenland John
Final Pr. ID: Sa4117
Authors: Dey Tapan, Wolters Paul, Jiang Lifeng, Goncharova Elena, Goncharov Dmitry, Zhyvylo Iryna, Lin Derek, Shah Maanvi, Saiyed Aisha, Neeli Sanjana, Kudryashova Tatiana, Greenland John
Keywords: Pulmonary hypertension , Pulmonary vascular biology , Pulmonary artery , Cell signaling
10 : 30 AM
Development and characterization of an ex vivo human precision-cut lung slice (hPCLS) system for target validation for pulmonary arterial hypertension
Kim Haejin, Lu Min, Goodwin Bryan, Jain Dhawal, Akram Muzaffar, Zhou Willa, Provencher Steeve, Lemay Sarah-eve, Bonnet Sebastien, Potus Francois, Montesinos Monica
Final Pr. ID: Sa4121
Authors: Kim Haejin, Lu Min, Goodwin Bryan, Jain Dhawal, Akram Muzaffar, Zhou Willa, Provencher Steeve, Lemay Sarah-eve, Bonnet Sebastien, Potus Francois, Montesinos Monica
Keywords: Pulmonary hypertension , Pulmonary artery
Hong Jason, Wong Brenda, Brownstein Adam, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh
Final Pr. ID: Sa4116
Authors: Hong Jason, Wong Brenda, Brownstein Adam, Graves Tammy, Aldred Micheala, Dai Zhiyu, Yang Xia, Eghbali Mansoureh
Keywords: Pulmonary hypertension , Pulmonary vascular biology , Transcriptomics
Besse Casandra, Puerta Cristian, Winicki Nolan, Hernandez Moises, Thistlethwaite Patricia
Final Pr. ID: Sa4124
Authors: Besse Casandra, Puerta Cristian, Winicki Nolan, Hernandez Moises, Thistlethwaite Patricia
Keywords: Pulmonary hypertension , Clinical trials , Molecular biology
10 : 30 AM
Development and characterization of an ex vivo human precision-cut lung slice (hPCLS) system for target validation for pulmonary arterial hypertension
Kim Haejin, Lu Min, Goodwin Bryan, Jain Dhawal, Akram Muzaffar, Zhou Willa, Provencher Steeve, Lemay Sarah-eve, Bonnet Sebastien, Potus Francois, Montesinos Monica
Final Pr. ID: Sa4121
Authors: Kim Haejin, Lu Min, Goodwin Bryan, Jain Dhawal, Akram Muzaffar, Zhou Willa, Provencher Steeve, Lemay Sarah-eve, Bonnet Sebastien, Potus Francois, Montesinos Monica
Keywords: Pulmonary hypertension , Pulmonary artery
10 : 30 AM
eQTL Analysis of the PAH Biomarker CCN2 Identifies a Novel SNP that Associates with Survival
Byrd Carly, Simpson Catherine, Kolb Todd, Pauciulo Michael, Nichols William, Ivy Dunbar, Hassoun Paul, Everett Allen, Austin Eric, Martin Lisa, Benza Raymond, Webb Amy, Schramm Jennifer, Yang Jun, Griffiths Megan, Brandal Stephanie, Damico Rachel, Vaidya Dhananjay
Final Pr. ID: Sa4122
Authors: Byrd Carly, Simpson Catherine, Kolb Todd, Pauciulo Michael, Nichols William, Ivy Dunbar, Hassoun Paul, Everett Allen, Austin Eric, Martin Lisa, Benza Raymond, Webb Amy, Schramm Jennifer, Yang Jun, Griffiths Megan, Brandal Stephanie, Damico Rachel, Vaidya Dhananjay
Keywords: Pulmonary hypertension , Genetics , Genome-wide association studies (GWAS) , Biomarkers , Risk Factors
10 : 30 AM
Individualized Interactomes from Pulmonary Arterial Hypertension Biopsies Predict Therapeutic Response: an In Silico Clinical Study
Wang Ruisheng, Harrington Elizabeth, Maron Brad, Ventetuolo Corey, Singh Navneet, Wathieu Henri, Baird Grayson, Cox-flaherty Katherine, Klinger James, Mullin Christopher, Pereira Mandy, Whittenhall Mary
Final Pr. ID: Sa4118
Authors: Wang Ruisheng, Harrington Elizabeth, Maron Brad, Ventetuolo Corey, Singh Navneet, Wathieu Henri, Baird Grayson, Cox-flaherty Katherine, Klinger James, Mullin Christopher, Pereira Mandy, Whittenhall Mary
Keywords: Pulmonary hypertension , Systems biology , Transcriptomics
10 : 30 AM
Network Analysis of Differentially Expressed Genes after Silencing Dynamin 2 in Pulmonary Arterial Hypertension
Wu Danchen, Das Gupta Asish, Chen Kuang-hueih, Hindmarch Charles, Hu Ting, Archer Stephen
Final Pr. ID: Sa4119
Authors: Wu Danchen, Das Gupta Asish, Chen Kuang-hueih, Hindmarch Charles, Hu Ting, Archer Stephen
Keywords: Pulmonary hypertension , Mitochondria
10 : 30 AM
Non-canonical CDC20 signaling promotes smooth muscle and adventitial fibroblasts hyper-proliferation and remodeling in pulmonary arterial hypertension
Dey Tapan, Wolters Paul, Jiang Lifeng, Goncharova Elena, Goncharov Dmitry, Zhyvylo Iryna, Lin Derek, Shah Maanvi, Saiyed Aisha, Neeli Sanjana, Kudryashova Tatiana, Greenland John
Final Pr. ID: Sa4117
Authors: Dey Tapan, Wolters Paul, Jiang Lifeng, Goncharova Elena, Goncharov Dmitry, Zhyvylo Iryna, Lin Derek, Shah Maanvi, Saiyed Aisha, Neeli Sanjana, Kudryashova Tatiana, Greenland John
Keywords: Pulmonary hypertension , Pulmonary vascular biology , Pulmonary artery , Cell signaling
10 : 30 AM
Single Cell Transcriptomics Unveils Novel Lung Capillary Endothelial Cell Populations and Their Crucial Roles
James Joel, Dekan Aleksandr, Bharti Dinesh, Valuparampil Varghese Mathews, Kacar Sedat, Niihori Maki, Rafikova Olga, Rafikov Ruslan
Final Pr. ID: Sa4123
Authors: James Joel, Dekan Aleksandr, Bharti Dinesh, Valuparampil Varghese Mathews, Kacar Sedat, Niihori Maki, Rafikova Olga, Rafikov Ruslan
Keywords: Endothelial , Endothelial function , Vascular development , Pulmonary circulation , Arteries
10 : 30 AM
Upregulation of Dynamin 2 (DNM2) Increases Mitochondrial Fission and Cell Proliferation in Pulmonary Arterial Hypertension
Das Gupta Asish, Yerramilli Siddartha, Jones Oliver, Hindmarch Charles, Potus Francois, Bonnet Sebastien, Archer Stephen, Chen Kuang-hueih, Wu Danchen, Lima Patricia, Martin Ashley, Mewburn Jeffrey, Al-qazazi Ruaa, Emon Isaac, Colpman Pierce
Final Pr. ID: Sa4120
Authors: Das Gupta Asish, Yerramilli Siddartha, Jones Oliver, Hindmarch Charles, Potus Francois, Bonnet Sebastien, Archer Stephen, Chen Kuang-hueih, Wu Danchen, Lima Patricia, Martin Ashley, Mewburn Jeffrey, Al-qazazi Ruaa, Emon Isaac, Colpman Pierce
Keywords: Pulmonary hypertension , Cell signaling , Cardiovascular , Cells , Cell physiology