American Heart Association
New Mechanisms to Control Hypercholesterolemia
Moderated Digital Poster Session
Basic Science Zone, Moderated Digital Poster 26
Nov 10th , 10:45 AM - 11:45 AM
10 : 45 AM
Cholesterol-Driven Monocyte mTORC1 Activation and Autophagy Suppression in Hypercholesterolemic Patients: A Translational Link to Atherosclerosis
Ajam Ali, Zhang Xiangyu, Liu Ziyang, Peroumal Doureradjou, Razani Babak
Final Pr. ID: MP2748
Authors: Ajam Ali, Zhang Xiangyu, Liu Ziyang, Peroumal Doureradjou, Razani Babak
Keywords: Atherosclerosis , Cardiovascular disease prevention , Autophagy
10 : 52 AM
HEPATIC DELIVERY OF MICRORNA-30C ANALOG C2 REDUCES PLASMA CHOLESTEROL IN MICE AND MONKEYS AND ATHEROSCLEROSIS IN MICE WITHOUT CAUSING LIVER INJURY
Prakash Binu, Carsons Steven, Kavanagh Kylie, Sheng Jia, Hussain Mahmood, Chang Zhihua, Krainiak Shannon, Gangula Bhargavi, Rajan Sujith, Prakashmurthy Chandana, Swati Swati, Pulatov Otabek, Temel Ryan
Final Pr. ID: MP2749
Authors: Prakash Binu, Carsons Steven, Kavanagh Kylie, Sheng Jia, Hussain Mahmood, Chang Zhihua, Krainiak Shannon, Gangula Bhargavi, Rajan Sujith, Prakashmurthy Chandana, Swati Swati, Pulatov Otabek, Temel Ryan
Keywords: Cholesterol-lowering drugs , Arteriosclerosis , Hypercholesterolemia , Inflammation , Metabolism
10 : 59 AM
Obicetrapib in combination with ezetimibe on top of atorvastatin regresses atherosclerotic plaque lesions in APOE*3-Leiden.CETP mice
Inia Jose, Stokman Geurt, Pieterman Elsbet, Princen Hans, Keijzer Nanda, Worms Nicole, Van Nieuwkoop Anita, Ditmarsch Marc, Jukema J, De Kleer Mathijs, Kastelein John, Van Den Hoek Anita
Final Pr. ID: MP2750
Authors: Inia Jose, Stokman Geurt, Pieterman Elsbet, Princen Hans, Keijzer Nanda, Worms Nicole, Van Nieuwkoop Anita, Ditmarsch Marc, Jukema J, De Kleer Mathijs, Kastelein John, Van Den Hoek Anita
Keywords: CETP inhibitors , Atherosclerosis , Lipoproteins , Cholesterol-lowering drugs
11 : 06 AM
Direct Vascular Endothelial Assessment Highlights the Pleotropic Anti-Inflammatory Properties of Statin Therapy: Findings from the American Heart Association Cardiometabolic Health Strategically Focused Research Network
Garshick Michael, Schlamp Maria Florencia, Giannarelli Chiara, Fisher Edward, Goldberg Ira, Berger Jeffrey, Boothman Isabelle, Barrett Tessa, Jindal Manila, Newman Jonathan, Fadzan Maja, Bredefeld Cindy, Levy Natalie, Akinlonu Adedoyin
Final Pr. ID: MP2751
Authors: Garshick Michael, Schlamp Maria Florencia, Giannarelli Chiara, Fisher Edward, Goldberg Ira, Berger Jeffrey, Boothman Isabelle, Barrett Tessa, Jindal Manila, Newman Jonathan, Fadzan Maja, Bredefeld Cindy, Levy Natalie, Akinlonu Adedoyin
Keywords: Endothelial , Statins , Lipids
11 : 13 AM
Trends in Adoption of the Familial Hypercholesterolemia Diagnostic Code E78.01 in U.S. Healthcare Settings from 2016 to 2024
Osei Jeffery, Sperling Laurence, Khoury Muin, Sun Yan
Final Pr. ID: MP2752
Authors: Osei Jeffery, Sperling Laurence, Khoury Muin, Sun Yan
Keywords: Hypercholesterolemia , Lipids , Coronary heart disease , LDL , Cholesterol-lowering drugs
11 : 20 AM
Olpasiran Outperforms Other Subcutaneous Lipoprotein(a)-Lowering Agents in Efficacy and Safety: A Network Meta-Analysis of Randomized Controlled Trials
Tanriverdi Lokman H., Dogan Muhammed Melih, Su Angela, Shan Ryan, Banach Maciej, Hernandez Adrian V.
Final Pr. ID: MP2753
Authors: Tanriverdi Lokman H., Dogan Muhammed Melih, Su Angela, Shan Ryan, Banach Maciej, Hernandez Adrian V.
Keywords: Atherosclerosis , Lipoproteins , Pharmacology , Evidence-based medicine , Hyperlipoproteinemia
10 : 45 AM
Cholesterol-Driven Monocyte mTORC1 Activation and Autophagy Suppression in Hypercholesterolemic Patients: A Translational Link to Atherosclerosis
Ajam Ali, Zhang Xiangyu, Liu Ziyang, Peroumal Doureradjou, Razani Babak
Final Pr. ID: MP2748
Authors: Ajam Ali, Zhang Xiangyu, Liu Ziyang, Peroumal Doureradjou, Razani Babak
Keywords: Atherosclerosis , Cardiovascular disease prevention , Autophagy
11 : 06 AM
Direct Vascular Endothelial Assessment Highlights the Pleotropic Anti-Inflammatory Properties of Statin Therapy: Findings from the American Heart Association Cardiometabolic Health Strategically Focused Research Network
Garshick Michael, Schlamp Maria Florencia, Giannarelli Chiara, Fisher Edward, Goldberg Ira, Berger Jeffrey, Boothman Isabelle, Barrett Tessa, Jindal Manila, Newman Jonathan, Fadzan Maja, Bredefeld Cindy, Levy Natalie, Akinlonu Adedoyin
Final Pr. ID: MP2751
Authors: Garshick Michael, Schlamp Maria Florencia, Giannarelli Chiara, Fisher Edward, Goldberg Ira, Berger Jeffrey, Boothman Isabelle, Barrett Tessa, Jindal Manila, Newman Jonathan, Fadzan Maja, Bredefeld Cindy, Levy Natalie, Akinlonu Adedoyin
Keywords: Endothelial , Statins , Lipids
10 : 52 AM
HEPATIC DELIVERY OF MICRORNA-30C ANALOG C2 REDUCES PLASMA CHOLESTEROL IN MICE AND MONKEYS AND ATHEROSCLEROSIS IN MICE WITHOUT CAUSING LIVER INJURY
Prakash Binu, Carsons Steven, Kavanagh Kylie, Sheng Jia, Hussain Mahmood, Chang Zhihua, Krainiak Shannon, Gangula Bhargavi, Rajan Sujith, Prakashmurthy Chandana, Swati Swati, Pulatov Otabek, Temel Ryan
Final Pr. ID: MP2749
Authors: Prakash Binu, Carsons Steven, Kavanagh Kylie, Sheng Jia, Hussain Mahmood, Chang Zhihua, Krainiak Shannon, Gangula Bhargavi, Rajan Sujith, Prakashmurthy Chandana, Swati Swati, Pulatov Otabek, Temel Ryan
Keywords: Cholesterol-lowering drugs , Arteriosclerosis , Hypercholesterolemia , Inflammation , Metabolism
10 : 59 AM
Obicetrapib in combination with ezetimibe on top of atorvastatin regresses atherosclerotic plaque lesions in APOE*3-Leiden.CETP mice
Inia Jose, Stokman Geurt, Pieterman Elsbet, Princen Hans, Keijzer Nanda, Worms Nicole, Van Nieuwkoop Anita, Ditmarsch Marc, Jukema J, De Kleer Mathijs, Kastelein John, Van Den Hoek Anita
Final Pr. ID: MP2750
Authors: Inia Jose, Stokman Geurt, Pieterman Elsbet, Princen Hans, Keijzer Nanda, Worms Nicole, Van Nieuwkoop Anita, Ditmarsch Marc, Jukema J, De Kleer Mathijs, Kastelein John, Van Den Hoek Anita
Keywords: CETP inhibitors , Atherosclerosis , Lipoproteins , Cholesterol-lowering drugs
11 : 20 AM
Olpasiran Outperforms Other Subcutaneous Lipoprotein(a)-Lowering Agents in Efficacy and Safety: A Network Meta-Analysis of Randomized Controlled Trials
Tanriverdi Lokman H., Dogan Muhammed Melih, Su Angela, Shan Ryan, Banach Maciej, Hernandez Adrian V.
Final Pr. ID: MP2753
Authors: Tanriverdi Lokman H., Dogan Muhammed Melih, Su Angela, Shan Ryan, Banach Maciej, Hernandez Adrian V.
Keywords: Atherosclerosis , Lipoproteins , Pharmacology , Evidence-based medicine , Hyperlipoproteinemia
11 : 13 AM
Trends in Adoption of the Familial Hypercholesterolemia Diagnostic Code E78.01 in U.S. Healthcare Settings from 2016 to 2024
Osei Jeffery, Sperling Laurence, Khoury Muin, Sun Yan
Final Pr. ID: MP2752
Authors: Osei Jeffery, Sperling Laurence, Khoury Muin, Sun Yan
Keywords: Hypercholesterolemia , Lipids , Coronary heart disease , LDL , Cholesterol-lowering drugs