American Heart Association
Groundbreaking Trials in Cardiometabolic Therapeutics
Late-Breaking Science
Main Event 1
Nov 8th , 08:30 AM - 09:45 AM
08 : 30 AM
DR10624, a First-In-Class, FGF21 Receptor/Glucagon Receptor/GLP-1 Receptor Triple Agonist, Rapidly and Significantly Reduced Triglycerides, Atherogenic Lipids, and Liver Fat in Patients With Severe Hypertriglyceridemia: Primary Results From a Randomized Phase 2 Trial.
Li Jianping, Zhou Zijian, Lv Lingchun, Gan Yulong, Wang Ying, Zhu Chaonan, Xu June, Huang Yanshan, Fang Yongliang, Zhang Long, Fan Yanting, Zhang Shu, Wang Liyun, Qu Yanling, Yin Guotian, Jiang Hongwei
Final Pr. ID: -
Authors: Li Jianping, Zhou Zijian, Lv Lingchun, Gan Yulong, Wang Ying, Zhu Chaonan, Xu June, Huang Yanshan, Fang Yongliang, Zhang Long, Fan Yanting, Zhang Shu, Wang Liyun, Qu Yanling, Yin Guotian, Jiang Hongwei
Keywords: Triglycerides , Dyslipidemia , HDL elevating therapies , Cholesterol-lowering drugs , Adiponectin
08 : 40 AM
Olezarsen in Patients with Severe Hypertriglyceridemia: The CORE-TIMI 72a and CORE2-TIMI 72b Trials
Marston Nicholas, Zhang Shuanglu, Goodrich Erica, Murphy Sabina, Xia Shuting, Li Dan, Tsimikas Sotirios, Giugliano Robert, Sabatine Marc, Bergmark Brian, Alexander Vickie, Prohaska Thomas, Kang Yu Mi, Moura Filipe, Zimerman Andre, Waldman Elaine, Weinland Julia
Final Pr. ID: -
Authors: Marston Nicholas, Zhang Shuanglu, Goodrich Erica, Murphy Sabina, Xia Shuting, Li Dan, Tsimikas Sotirios, Giugliano Robert, Sabatine Marc, Bergmark Brian, Alexander Vickie, Prohaska Thomas, Kang Yu Mi, Moura Filipe, Zimerman Andre, Waldman Elaine, Weinland Julia
Keywords: Triglycerides , Lipids , Hypertriglyceridemia , Pancreatitis , Prevention
Lingvay Ildiko, Rosenson Robert
Final Pr. ID: -
Authors: Lingvay Ildiko, Rosenson Robert
08 : 56 AM
First-in-Human Phase 1 Clinical Trial of a CRISPR-Cas9 Gene Editing Therapy Targeting ANGPTL3
Nicholls Stephen, Patel Naimish, Duran Jason, Nissen Steven, Laffin Luke, Scott Russell, Clifton Peter, Baker John, Sarraju Ashish, Singh Shweta, Xu Huansheng, Nielsen Jennifer
Final Pr. ID: -
Authors: Nicholls Stephen, Patel Naimish, Duran Jason, Nissen Steven, Laffin Luke, Scott Russell, Clifton Peter, Baker John, Sarraju Ashish, Singh Shweta, Xu Huansheng, Nielsen Jennifer
Keywords: Gene therapy , Lipids , Risk Factors , Prevention
Gaudet Daniel
Final Pr. ID: -
Authors: Gaudet Daniel
09 : 10 AM
Effect of Evolocumab in Patients at High Cardiovascular Risk without Prior Myocardial Infarction or Stroke: Primary Results of the VESALIUS-CV trial
Bohula Erin, Wang Huei, Cyrille Marcoli, Paiva Da Silva Lima Gabriel, Giugliano Robert, Sabatine Marc, Marston Nicholas, Bhatia Ajay, De Ferrari Gaetano Maria, Leiter Lawrence, Nicolau Jose, Park Jeong-gun, Murphy Sabina, Walsh Emileigh
Final Pr. ID: -
Authors: Bohula Erin, Wang Huei, Cyrille Marcoli, Paiva Da Silva Lima Gabriel, Giugliano Robert, Sabatine Marc, Marston Nicholas, Bhatia Ajay, De Ferrari Gaetano Maria, Leiter Lawrence, Nicolau Jose, Park Jeong-gun, Murphy Sabina, Walsh Emileigh
Keywords: Apolipoproteins , Lipids , PCSK9 , Outcomes , Lipoproteins
Morris Pamela
Final Pr. ID: -
Authors: Morris Pamela
Ballantyne Christie
Final Pr. ID: -
Authors: Ballantyne Christie
Lingvay Ildiko, Rosenson Robert
Final Pr. ID: -
Authors: Lingvay Ildiko, Rosenson Robert
Gaudet Daniel
Final Pr. ID: -
Authors: Gaudet Daniel
Morris Pamela
Final Pr. ID: -
Authors: Morris Pamela
08 : 30 AM
DR10624, a First-In-Class, FGF21 Receptor/Glucagon Receptor/GLP-1 Receptor Triple Agonist, Rapidly and Significantly Reduced Triglycerides, Atherogenic Lipids, and Liver Fat in Patients With Severe Hypertriglyceridemia: Primary Results From a Randomized Phase 2 Trial.
Li Jianping, Zhou Zijian, Lv Lingchun, Gan Yulong, Wang Ying, Zhu Chaonan, Xu June, Huang Yanshan, Fang Yongliang, Zhang Long, Fan Yanting, Zhang Shu, Wang Liyun, Qu Yanling, Yin Guotian, Jiang Hongwei
Final Pr. ID: -
Authors: Li Jianping, Zhou Zijian, Lv Lingchun, Gan Yulong, Wang Ying, Zhu Chaonan, Xu June, Huang Yanshan, Fang Yongliang, Zhang Long, Fan Yanting, Zhang Shu, Wang Liyun, Qu Yanling, Yin Guotian, Jiang Hongwei
Keywords: Triglycerides , Dyslipidemia , HDL elevating therapies , Cholesterol-lowering drugs , Adiponectin
09 : 10 AM
Effect of Evolocumab in Patients at High Cardiovascular Risk without Prior Myocardial Infarction or Stroke: Primary Results of the VESALIUS-CV trial
Bohula Erin, Wang Huei, Cyrille Marcoli, Paiva Da Silva Lima Gabriel, Giugliano Robert, Sabatine Marc, Marston Nicholas, Bhatia Ajay, De Ferrari Gaetano Maria, Leiter Lawrence, Nicolau Jose, Park Jeong-gun, Murphy Sabina, Walsh Emileigh
Final Pr. ID: -
Authors: Bohula Erin, Wang Huei, Cyrille Marcoli, Paiva Da Silva Lima Gabriel, Giugliano Robert, Sabatine Marc, Marston Nicholas, Bhatia Ajay, De Ferrari Gaetano Maria, Leiter Lawrence, Nicolau Jose, Park Jeong-gun, Murphy Sabina, Walsh Emileigh
Keywords: Apolipoproteins , Lipids , PCSK9 , Outcomes , Lipoproteins
08 : 56 AM
First-in-Human Phase 1 Clinical Trial of a CRISPR-Cas9 Gene Editing Therapy Targeting ANGPTL3
Nicholls Stephen, Patel Naimish, Duran Jason, Nissen Steven, Laffin Luke, Scott Russell, Clifton Peter, Baker John, Sarraju Ashish, Singh Shweta, Xu Huansheng, Nielsen Jennifer
Final Pr. ID: -
Authors: Nicholls Stephen, Patel Naimish, Duran Jason, Nissen Steven, Laffin Luke, Scott Russell, Clifton Peter, Baker John, Sarraju Ashish, Singh Shweta, Xu Huansheng, Nielsen Jennifer
Keywords: Gene therapy , Lipids , Risk Factors , Prevention
08 : 40 AM
Olezarsen in Patients with Severe Hypertriglyceridemia: The CORE-TIMI 72a and CORE2-TIMI 72b Trials
Marston Nicholas, Zhang Shuanglu, Goodrich Erica, Murphy Sabina, Xia Shuting, Li Dan, Tsimikas Sotirios, Giugliano Robert, Sabatine Marc, Bergmark Brian, Alexander Vickie, Prohaska Thomas, Kang Yu Mi, Moura Filipe, Zimerman Andre, Waldman Elaine, Weinland Julia
Final Pr. ID: -
Authors: Marston Nicholas, Zhang Shuanglu, Goodrich Erica, Murphy Sabina, Xia Shuting, Li Dan, Tsimikas Sotirios, Giugliano Robert, Sabatine Marc, Bergmark Brian, Alexander Vickie, Prohaska Thomas, Kang Yu Mi, Moura Filipe, Zimerman Andre, Waldman Elaine, Weinland Julia
Keywords: Triglycerides , Lipids , Hypertriglyceridemia , Pancreatitis , Prevention
Ballantyne Christie
Final Pr. ID: -
Authors: Ballantyne Christie