American Heart Association
Polygenic Risk Stratification in Cardiovascular Disease
Moderated Digital Poster Session
Zone 1, Moderated Digital Poster 2
Nov 16th , 02:50 PM - 04:15 PM
02 : 50 PM
Polygenic Risk Stratification for Risk of Venous Thromboembolism: Analysis of >31K Individuals from the Women’s Genome Health Study and JUPITER trials
Rosamilia Michael, Marston Nicholas, Melloni Giorgio, Kamanu Frederick, Sabatine Marc, Ruff Christian, Ridker Paul, Chasman Daniel
Final Pr. ID: MDP57
Authors: Rosamilia Michael, Marston Nicholas, Melloni Giorgio, Kamanu Frederick, Sabatine Marc, Ruff Christian, Ridker Paul, Chasman Daniel
Keywords: Venous thrombosis , Polygenic Risk , Prevention , Statins , Aspirin
03 : 00 PM
Effect of Disclosing a Polygenic Risk Score for Coronary Heart Disease on Adverse Cardiovascular Events: 10-year Follow-up of the MI-GENES Randomized Clinical Trial
Naderian Mohammadreza, Hamed Marwan, Vaseem Ali, Norland Kristjan, Dikilitas Ozan, Teymourzadeh Azin, Bailey Kent, Kullo Iftikhar
Final Pr. ID: MDP58
Authors: Naderian Mohammadreza, Hamed Marwan, Vaseem Ali, Norland Kristjan, Dikilitas Ozan, Teymourzadeh Azin, Bailey Kent, Kullo Iftikhar
Keywords: Polygenic Risk , Atherosclerosis , Coronary artery disease , Statins , Prevention
03 : 10 PM
Machine Learning Uncovers the Contribution of Rare Genetic Variants and Enhances Risk Prediction for Coronary Artery Disease in the Japanese Population
Ieki Hirotaka, Onouchi Yoshihiro, Kamatani Yoichiro, Terao Chikashi, Snyder Michael, Komuro Issei, Ito Kaoru, Zhang Sai, Koyama Satoshi, Miyazawa Kazuo, Yoshida Hiroki, Kurosawa Ryo, Enzan Nobuyuki, Ozaki Kouichi
Final Pr. ID: MDP59
Authors: Ieki Hirotaka, Onouchi Yoshihiro, Kamatani Yoichiro, Terao Chikashi, Snyder Michael, Komuro Issei, Ito Kaoru, Zhang Sai, Koyama Satoshi, Miyazawa Kazuo, Yoshida Hiroki, Kurosawa Ryo, Enzan Nobuyuki, Ozaki Kouichi
Keywords: Coronary artery disease , Genetics , Machine Learning , Polygenic Risk , Myocardial infarction
03 : 20 PM
Epidemiologic and genetic associations between proteomic markers and thoracic aortic diameter
Wells Alexander, Brundage James, Zamirpour Siavash, Pirruccello James
Final Pr. ID: MDP60
Authors: Wells Alexander, Brundage James, Zamirpour Siavash, Pirruccello James
Keywords: Thoracic Aorta , Aortic aneurysm , Biomarkers , Proteins , Genetics
03 : 30 PM
An Integrated Germline and Somatic Genomic Model Improves Risk Prediction for Coronary Artery Disease
Kim Min Seo, Zhang Rufan, Liu Zhaoqi, A Yunga, Ellinor Patrick, Natarajan Pradeep, Wang Minxian, Fahed Akl, Yang Xiong, Uddin Md Mesbah, Nakao Tetsushi, Cho So Mi Jemma, Koyama Satoshi, Zhu Xinyu, Xu Tingfeng, Reeskamp Laurens
Final Pr. ID: MDP61
Authors: Kim Min Seo, Zhang Rufan, Liu Zhaoqi, A Yunga, Ellinor Patrick, Natarajan Pradeep, Wang Minxian, Fahed Akl, Yang Xiong, Uddin Md Mesbah, Nakao Tetsushi, Cho So Mi Jemma, Koyama Satoshi, Zhu Xinyu, Xu Tingfeng, Reeskamp Laurens
Keywords: Coronary artery disease , Prediction model , Genetics , Genomics , Atherosclerosis
03 : 40 PM
Metabolomic Markers of Aortic Stenosis Development: the Atherosclerosis Risk in Communities (ARIC) Study
Shelbaya Khaled, Lamberson Victoria, Yang Yimin, Zhou Peidi, Alkis Taryn, Matsushita Kuni, Yu Bing, Shah Amil
Final Pr. ID: MDP62
Authors: Shelbaya Khaled, Lamberson Victoria, Yang Yimin, Zhou Peidi, Alkis Taryn, Matsushita Kuni, Yu Bing, Shah Amil
Keywords: Aortic valve stenosis , Metabolomics , Echocardiography
03 : 50 PM
Genome wide association study for residualized apolipoprotein B elucidates its role in coronary artery disease risk
Zhang Selena, Koyama Satoshi, Haidermota Sara, Hornsby Whitney, Honigberg Michael, Ellinor Patrick, Natarajan Pradeep
Final Pr. ID: MDP63
Authors: Zhang Selena, Koyama Satoshi, Haidermota Sara, Hornsby Whitney, Honigberg Michael, Ellinor Patrick, Natarajan Pradeep
Keywords: Genome-wide association studies (GWAS) , Lipids , Apolipoproteins , Coronary artery disease , Big Data
04 : 00 PM
A Polygenic Score to Identify Risk of Incident Stroke and Benefit from Primary Prevention Statin Therapy
Mcclintick Daniel, Kamanu Frederick, Melloni Giorgio, Sabatine Marc, Ruff Christian, Ridker Paul, Chasman Daniel, Marston Nicholas
Final Pr. ID: MDP64
Authors: Mcclintick Daniel, Kamanu Frederick, Melloni Giorgio, Sabatine Marc, Ruff Christian, Ridker Paul, Chasman Daniel, Marston Nicholas
Keywords: Stroke , Genetics , Polygenic Risk , Statins , Prevention
04 : 00 PM
A Polygenic Score to Identify Risk of Incident Stroke and Benefit from Primary Prevention Statin Therapy
Mcclintick Daniel, Kamanu Frederick, Melloni Giorgio, Sabatine Marc, Ruff Christian, Ridker Paul, Chasman Daniel, Marston Nicholas
Final Pr. ID: MDP64
Authors: Mcclintick Daniel, Kamanu Frederick, Melloni Giorgio, Sabatine Marc, Ruff Christian, Ridker Paul, Chasman Daniel, Marston Nicholas
Keywords: Stroke , Genetics , Polygenic Risk , Statins , Prevention
03 : 30 PM
An Integrated Germline and Somatic Genomic Model Improves Risk Prediction for Coronary Artery Disease
Kim Min Seo, Zhang Rufan, Liu Zhaoqi, A Yunga, Ellinor Patrick, Natarajan Pradeep, Wang Minxian, Fahed Akl, Yang Xiong, Uddin Md Mesbah, Nakao Tetsushi, Cho So Mi Jemma, Koyama Satoshi, Zhu Xinyu, Xu Tingfeng, Reeskamp Laurens
Final Pr. ID: MDP61
Authors: Kim Min Seo, Zhang Rufan, Liu Zhaoqi, A Yunga, Ellinor Patrick, Natarajan Pradeep, Wang Minxian, Fahed Akl, Yang Xiong, Uddin Md Mesbah, Nakao Tetsushi, Cho So Mi Jemma, Koyama Satoshi, Zhu Xinyu, Xu Tingfeng, Reeskamp Laurens
Keywords: Coronary artery disease , Prediction model , Genetics , Genomics , Atherosclerosis
03 : 00 PM
Effect of Disclosing a Polygenic Risk Score for Coronary Heart Disease on Adverse Cardiovascular Events: 10-year Follow-up of the MI-GENES Randomized Clinical Trial
Naderian Mohammadreza, Hamed Marwan, Vaseem Ali, Norland Kristjan, Dikilitas Ozan, Teymourzadeh Azin, Bailey Kent, Kullo Iftikhar
Final Pr. ID: MDP58
Authors: Naderian Mohammadreza, Hamed Marwan, Vaseem Ali, Norland Kristjan, Dikilitas Ozan, Teymourzadeh Azin, Bailey Kent, Kullo Iftikhar
Keywords: Polygenic Risk , Atherosclerosis , Coronary artery disease , Statins , Prevention
03 : 20 PM
Epidemiologic and genetic associations between proteomic markers and thoracic aortic diameter
Wells Alexander, Brundage James, Zamirpour Siavash, Pirruccello James
Final Pr. ID: MDP60
Authors: Wells Alexander, Brundage James, Zamirpour Siavash, Pirruccello James
Keywords: Thoracic Aorta , Aortic aneurysm , Biomarkers , Proteins , Genetics
03 : 50 PM
Genome wide association study for residualized apolipoprotein B elucidates its role in coronary artery disease risk
Zhang Selena, Koyama Satoshi, Haidermota Sara, Hornsby Whitney, Honigberg Michael, Ellinor Patrick, Natarajan Pradeep
Final Pr. ID: MDP63
Authors: Zhang Selena, Koyama Satoshi, Haidermota Sara, Hornsby Whitney, Honigberg Michael, Ellinor Patrick, Natarajan Pradeep
Keywords: Genome-wide association studies (GWAS) , Lipids , Apolipoproteins , Coronary artery disease , Big Data
03 : 10 PM
Machine Learning Uncovers the Contribution of Rare Genetic Variants and Enhances Risk Prediction for Coronary Artery Disease in the Japanese Population
Ieki Hirotaka, Onouchi Yoshihiro, Kamatani Yoichiro, Terao Chikashi, Snyder Michael, Komuro Issei, Ito Kaoru, Zhang Sai, Koyama Satoshi, Miyazawa Kazuo, Yoshida Hiroki, Kurosawa Ryo, Enzan Nobuyuki, Ozaki Kouichi
Final Pr. ID: MDP59
Authors: Ieki Hirotaka, Onouchi Yoshihiro, Kamatani Yoichiro, Terao Chikashi, Snyder Michael, Komuro Issei, Ito Kaoru, Zhang Sai, Koyama Satoshi, Miyazawa Kazuo, Yoshida Hiroki, Kurosawa Ryo, Enzan Nobuyuki, Ozaki Kouichi
Keywords: Coronary artery disease , Genetics , Machine Learning , Polygenic Risk , Myocardial infarction
03 : 40 PM
Metabolomic Markers of Aortic Stenosis Development: the Atherosclerosis Risk in Communities (ARIC) Study
Shelbaya Khaled, Lamberson Victoria, Yang Yimin, Zhou Peidi, Alkis Taryn, Matsushita Kuni, Yu Bing, Shah Amil
Final Pr. ID: MDP62
Authors: Shelbaya Khaled, Lamberson Victoria, Yang Yimin, Zhou Peidi, Alkis Taryn, Matsushita Kuni, Yu Bing, Shah Amil
Keywords: Aortic valve stenosis , Metabolomics , Echocardiography
02 : 50 PM
Polygenic Risk Stratification for Risk of Venous Thromboembolism: Analysis of >31K Individuals from the Women’s Genome Health Study and JUPITER trials
Rosamilia Michael, Marston Nicholas, Melloni Giorgio, Kamanu Frederick, Sabatine Marc, Ruff Christian, Ridker Paul, Chasman Daniel
Final Pr. ID: MDP57
Authors: Rosamilia Michael, Marston Nicholas, Melloni Giorgio, Kamanu Frederick, Sabatine Marc, Ruff Christian, Ridker Paul, Chasman Daniel
Keywords: Venous thrombosis , Polygenic Risk , Prevention , Statins , Aspirin