American Heart Association
Latest Advances in Human Genetics and Genomics
Moderated Digital Poster Session
Zone 1, Moderated Digital Poster 2
Nov 16th , 12:50 PM - 02:15 PM
12 : 50 PM
A Hypertrophic Cardiomyopathy Polygenic Score Modifies Penetrance of Pathogenic Hypertrophic and Dilated Cardiomyopathy Variants in Opposite Directions
Abramowitz Sarah, Hoffman-andrews Lily, Depaolo John, Judy Renae, Owens Anjali, Damrauer Scott, Levin Michael
Final Pr. ID: MDP49
Authors: Abramowitz Sarah, Hoffman-andrews Lily, Depaolo John, Judy Renae, Owens Anjali, Damrauer Scott, Levin Michael
Keywords: Polygenic Risk , Hypertrophic cardiomyopathy , Genomics , Cardiomyopathy , Titin
01 : 00 PM
Multi-trait analysis identifies 307 genomic loci for thoracic aortic diameter and disease
Zamirpour Siavash, Depaolo John, Brundage James, Damrauer Scott, Pirruccello James
Final Pr. ID: MDP50
Authors: Zamirpour Siavash, Depaolo John, Brundage James, Damrauer Scott, Pirruccello James
Keywords: Thoracic Aorta , Aortic aneurysm , Aortic Dissection , Genome-wide association studies (GWAS) , Polygenic Risk
01 : 10 PM
Penetrance and Phenotype Conversion Rate of Genetic Hypertrophic Cardiomyopathy in an Academic Biobank
Shin Joseph, Small Aeron, Zawatsky Carrie, Fifer Michael, Tower-rader Albree, Green Robert, Lebo Matthew, Natarajan Pradeep
Final Pr. ID: MDP51
Authors: Shin Joseph, Small Aeron, Zawatsky Carrie, Fifer Michael, Tower-rader Albree, Green Robert, Lebo Matthew, Natarajan Pradeep
Keywords: Hypertrophic cardiomyopathy , Genetic testing
01 : 20 PM
Age-stratified Monogenic and Polygenic Contributions for Atrial Fibrillation in the All of Us Research Program
Chen Zhanlin, Gordon Adam, Webster Gregory
Final Pr. ID: MDP52
Authors: Chen Zhanlin, Gordon Adam, Webster Gregory
Keywords: Atrial fibrillation , Genetic testing , Genomics , Biomedical informatics , Risk Factors
01 : 30 PM
Genetic Insights into Chronic Thromboembolic Pulmonary Hypertension: Uncovering Immune Mechanisms in the Chinese Population
Duo Mengjie, Zou Bingzhang, Zhang Zhu, Zhai Zhenguo, Wang Chen
Final Pr. ID: MDP53
Authors: Duo Mengjie, Zou Bingzhang, Zhang Zhu, Zhai Zhenguo, Wang Chen
Keywords: Genome-wide association studies (GWAS) , Genomics , Pulmonary hypertension , Pulmonary embolism , Transcriptomics
01 : 40 PM
Genome-wide association study of aortic stiffness derived from deep learning in CMR images of 45,789 individuals identifies loci linked with cell-matrix structure
Paliwal Nikhil, Henry Albert, Finan Chris, Davies Rhodri, Hughes Alun, Williams Bryan, Malarstig Anders, Lumbers Tom, Hingorani Aroon
Final Pr. ID: MDP54
Authors: Paliwal Nikhil, Henry Albert, Finan Chris, Davies Rhodri, Hughes Alun, Williams Bryan, Malarstig Anders, Lumbers Tom, Hingorani Aroon
Keywords: Genome-wide association studies (GWAS) , Cardiac MRI , Aorta , Genetics , Deep learning
01 : 50 PM
Genetic Determinant for Prognosis of Dilated Cardiomyopathy: The role of NAV3 in Cardiac Fibrosis
Wang Min, Merlo Marco, Sinagra Gianfranco, Pinet Florence, Krejci Jan, Liu Duan, Weinshilboum Richard, Pereira Naveen, Wang Li, Ghazal Rachad, Seal Mayah, Nguyen Thanh Thanh, Mcnamara Dennis, Barlera Simona, Pileggi Silvana, Mestroni Luisa
Final Pr. ID: MDP55
Authors: Wang Min, Merlo Marco, Sinagra Gianfranco, Pinet Florence, Krejci Jan, Liu Duan, Weinshilboum Richard, Pereira Naveen, Wang Li, Ghazal Rachad, Seal Mayah, Nguyen Thanh Thanh, Mcnamara Dennis, Barlera Simona, Pileggi Silvana, Mestroni Luisa
Keywords: Fibrosis
02 : 00 PM
Prevalence, Penetrance, and Phenotypic Manifestation of Incidental Cardiomyopathy-Associated Genetic Variants in a Quaternary Medical Center-based Population
Figueiral Marta, Fazzini Luca, Tan-arroyo Jennifer, Olson Rory, Bublitz Josh, Olson Janet, Klee Eric, Pereira Naveen
Final Pr. ID: MDP56
Authors: Figueiral Marta, Fazzini Luca, Tan-arroyo Jennifer, Olson Rory, Bublitz Josh, Olson Janet, Klee Eric, Pereira Naveen
Keywords: Cardiomyopathy , Heart failure , adult , Genetic testing , Gene mutations
12 : 50 PM
A Hypertrophic Cardiomyopathy Polygenic Score Modifies Penetrance of Pathogenic Hypertrophic and Dilated Cardiomyopathy Variants in Opposite Directions
Abramowitz Sarah, Hoffman-andrews Lily, Depaolo John, Judy Renae, Owens Anjali, Damrauer Scott, Levin Michael
Final Pr. ID: MDP49
Authors: Abramowitz Sarah, Hoffman-andrews Lily, Depaolo John, Judy Renae, Owens Anjali, Damrauer Scott, Levin Michael
Keywords: Polygenic Risk , Hypertrophic cardiomyopathy , Genomics , Cardiomyopathy , Titin
01 : 20 PM
Age-stratified Monogenic and Polygenic Contributions for Atrial Fibrillation in the All of Us Research Program
Chen Zhanlin, Gordon Adam, Webster Gregory
Final Pr. ID: MDP52
Authors: Chen Zhanlin, Gordon Adam, Webster Gregory
Keywords: Atrial fibrillation , Genetic testing , Genomics , Biomedical informatics , Risk Factors
01 : 50 PM
Genetic Determinant for Prognosis of Dilated Cardiomyopathy: The role of NAV3 in Cardiac Fibrosis
Wang Min, Merlo Marco, Sinagra Gianfranco, Pinet Florence, Krejci Jan, Liu Duan, Weinshilboum Richard, Pereira Naveen, Wang Li, Ghazal Rachad, Seal Mayah, Nguyen Thanh Thanh, Mcnamara Dennis, Barlera Simona, Pileggi Silvana, Mestroni Luisa
Final Pr. ID: MDP55
Authors: Wang Min, Merlo Marco, Sinagra Gianfranco, Pinet Florence, Krejci Jan, Liu Duan, Weinshilboum Richard, Pereira Naveen, Wang Li, Ghazal Rachad, Seal Mayah, Nguyen Thanh Thanh, Mcnamara Dennis, Barlera Simona, Pileggi Silvana, Mestroni Luisa
Keywords: Fibrosis
01 : 30 PM
Genetic Insights into Chronic Thromboembolic Pulmonary Hypertension: Uncovering Immune Mechanisms in the Chinese Population
Duo Mengjie, Zou Bingzhang, Zhang Zhu, Zhai Zhenguo, Wang Chen
Final Pr. ID: MDP53
Authors: Duo Mengjie, Zou Bingzhang, Zhang Zhu, Zhai Zhenguo, Wang Chen
Keywords: Genome-wide association studies (GWAS) , Genomics , Pulmonary hypertension , Pulmonary embolism , Transcriptomics
01 : 40 PM
Genome-wide association study of aortic stiffness derived from deep learning in CMR images of 45,789 individuals identifies loci linked with cell-matrix structure
Paliwal Nikhil, Henry Albert, Finan Chris, Davies Rhodri, Hughes Alun, Williams Bryan, Malarstig Anders, Lumbers Tom, Hingorani Aroon
Final Pr. ID: MDP54
Authors: Paliwal Nikhil, Henry Albert, Finan Chris, Davies Rhodri, Hughes Alun, Williams Bryan, Malarstig Anders, Lumbers Tom, Hingorani Aroon
Keywords: Genome-wide association studies (GWAS) , Cardiac MRI , Aorta , Genetics , Deep learning
01 : 00 PM
Multi-trait analysis identifies 307 genomic loci for thoracic aortic diameter and disease
Zamirpour Siavash, Depaolo John, Brundage James, Damrauer Scott, Pirruccello James
Final Pr. ID: MDP50
Authors: Zamirpour Siavash, Depaolo John, Brundage James, Damrauer Scott, Pirruccello James
Keywords: Thoracic Aorta , Aortic aneurysm , Aortic Dissection , Genome-wide association studies (GWAS) , Polygenic Risk
01 : 10 PM
Penetrance and Phenotype Conversion Rate of Genetic Hypertrophic Cardiomyopathy in an Academic Biobank
Shin Joseph, Small Aeron, Zawatsky Carrie, Fifer Michael, Tower-rader Albree, Green Robert, Lebo Matthew, Natarajan Pradeep
Final Pr. ID: MDP51
Authors: Shin Joseph, Small Aeron, Zawatsky Carrie, Fifer Michael, Tower-rader Albree, Green Robert, Lebo Matthew, Natarajan Pradeep
Keywords: Hypertrophic cardiomyopathy , Genetic testing
02 : 00 PM
Prevalence, Penetrance, and Phenotypic Manifestation of Incidental Cardiomyopathy-Associated Genetic Variants in a Quaternary Medical Center-based Population
Figueiral Marta, Fazzini Luca, Tan-arroyo Jennifer, Olson Rory, Bublitz Josh, Olson Janet, Klee Eric, Pereira Naveen
Final Pr. ID: MDP56
Authors: Figueiral Marta, Fazzini Luca, Tan-arroyo Jennifer, Olson Rory, Bublitz Josh, Olson Janet, Klee Eric, Pereira Naveen
Keywords: Cardiomyopathy , Heart failure , adult , Genetic testing , Gene mutations