American Heart Association
Translational Basic Science Oral Abstracts I
Oral Abstract Session
Room 515B
Feb 6th , 07:30 AM - 09:00 AM
07 : 30 AM
A First-in-Class Humanized Antibody Fragment Targeting Platelet Glycoprotein Ibα: A Comprehensive Preclinical Study of CA1001 for the Treatment of Acute Ischemic Stroke
Xu Xiaohong, Lei Xi, Zhu Guangheng, Liu Zhenze, Hu Xudong, Slavkovic Sladjana, Neves Miguel, Ma Wenjing, Xie Huifang, Preeti Preeti, Yu Ruoying, Shaykhalishahi Hamed, Zhang Cheng, Shen Chuanbin, Li Bei, Tang Naping, Chang Yan, Xiang Qian, Cui Yimin, Ni Heyu
Final Pr. ID: 89
Authors: Xu Xiaohong, Lei Xi, Zhu Guangheng, Liu Zhenze, Hu Xudong, Slavkovic Sladjana, Neves Miguel, Ma Wenjing, Xie Huifang, Preeti Preeti, Yu Ruoying, Shaykhalishahi Hamed, Zhang Cheng, Shen Chuanbin, Li Bei, Tang Naping, Chang Yan, Xiang Qian, Cui Yimin, Ni Heyu
Keywords: Ischemic stroke , Reperfusion injury , Antithrombotic therapy , Pharmacology , Antibodies
07 : 42 AM
Astrocytic Cluster of Differentiation 38 Contributes to Hippocampal Synaptic Plasticity Deficits following Focal Cerebral Ischemia
Jackson Charles, Waits Paxton, Browning Sydney, Orfila James, Herson Paco
Final Pr. ID: 90
Authors: Jackson Charles, Waits Paxton, Browning Sydney, Orfila James, Herson Paco
Keywords: Cellular electrophysiology , Cognitive impairment , Transgenic models , Gene therapy , Ischemic stroke
Do Trang, Couture Lucy, Guzman Gary, Delevati Colpo Gabriela, Khan Romeesa, West Bryce, Devlin Patrick, Cahuiche Ana, St Denis Anna, Roh Solji, Venna Venugopal, Mccullough Louise, Ritzel Rodney
Final Pr. ID: 91
Authors: Do Trang, Couture Lucy, Guzman Gary, Delevati Colpo Gabriela, Khan Romeesa, West Bryce, Devlin Patrick, Cahuiche Ana, St Denis Anna, Roh Solji, Venna Venugopal, Mccullough Louise, Ritzel Rodney
Keywords: Ischemic stroke , Lipids
08 : 06 AM
Blocking the VCAM1-VLA4 axis prevents cognitive decline in a mouse model of infarct-induced neurodegeneration
Zera Kristy, Bradshaw Karen, Zhu Li, Hahn Oliver, Foltz Aulden, Peterson Todd, Yousef Hanadie, Lee Davis, Mayne Elizabeth, Wyss-coray Tony, Buckwalter Marion
Final Pr. ID: 92
Authors: Zera Kristy, Bradshaw Karen, Zhu Li, Hahn Oliver, Foltz Aulden, Peterson Todd, Yousef Hanadie, Lee Davis, Mayne Elizabeth, Wyss-coray Tony, Buckwalter Marion
Keywords: Blood-brain barrier , Behavior , Cognitive impairment , Inflammation , Leukocytes
08 : 18 AM
Increased IFN-γ Levels in African American Women Following Ischemic Stroke: A Study of Ethnic Disparities in Plasma Biomarkers
Sumani Destiny, Dongarwar Deepa, El Hamamy Ahmad, Delevati Colpo Gabriela, Couture Lucy, Li Jun
Final Pr. ID: 93
Authors: Sumani Destiny, Dongarwar Deepa, El Hamamy Ahmad, Delevati Colpo Gabriela, Couture Lucy, Li Jun
Keywords: Stroke , Inflammation and inflammatory markers , Ethnicity
Morais Andreia, Lynch Kirsten, Imai Takahiko, Jin Xuyan, Aykan Sanem A, Lamb Jessica, Nagarkatti Karisma, Lyden Patrick, Ayata Cenk
Final Pr. ID: 94
Authors: Morais Andreia, Lynch Kirsten, Imai Takahiko, Jin Xuyan, Aykan Sanem A, Lamb Jessica, Nagarkatti Karisma, Lyden Patrick, Ayata Cenk
Hu Jinglong, Chen Yan, Xu Yun
Final Pr. ID: 95
Authors: Hu Jinglong, Chen Yan, Xu Yun
Keywords: Ischemic stroke , Neuroprotection , Inflammation
07 : 30 AM
A First-in-Class Humanized Antibody Fragment Targeting Platelet Glycoprotein Ibα: A Comprehensive Preclinical Study of CA1001 for the Treatment of Acute Ischemic Stroke
Xu Xiaohong, Lei Xi, Zhu Guangheng, Liu Zhenze, Hu Xudong, Slavkovic Sladjana, Neves Miguel, Ma Wenjing, Xie Huifang, Preeti Preeti, Yu Ruoying, Shaykhalishahi Hamed, Zhang Cheng, Shen Chuanbin, Li Bei, Tang Naping, Chang Yan, Xiang Qian, Cui Yimin, Ni Heyu
Final Pr. ID: 89
Authors: Xu Xiaohong, Lei Xi, Zhu Guangheng, Liu Zhenze, Hu Xudong, Slavkovic Sladjana, Neves Miguel, Ma Wenjing, Xie Huifang, Preeti Preeti, Yu Ruoying, Shaykhalishahi Hamed, Zhang Cheng, Shen Chuanbin, Li Bei, Tang Naping, Chang Yan, Xiang Qian, Cui Yimin, Ni Heyu
Keywords: Ischemic stroke , Reperfusion injury , Antithrombotic therapy , Pharmacology , Antibodies
07 : 42 AM
Astrocytic Cluster of Differentiation 38 Contributes to Hippocampal Synaptic Plasticity Deficits following Focal Cerebral Ischemia
Jackson Charles, Waits Paxton, Browning Sydney, Orfila James, Herson Paco
Final Pr. ID: 90
Authors: Jackson Charles, Waits Paxton, Browning Sydney, Orfila James, Herson Paco
Keywords: Cellular electrophysiology , Cognitive impairment , Transgenic models , Gene therapy , Ischemic stroke
08 : 06 AM
Blocking the VCAM1-VLA4 axis prevents cognitive decline in a mouse model of infarct-induced neurodegeneration
Zera Kristy, Bradshaw Karen, Zhu Li, Hahn Oliver, Foltz Aulden, Peterson Todd, Yousef Hanadie, Lee Davis, Mayne Elizabeth, Wyss-coray Tony, Buckwalter Marion
Final Pr. ID: 92
Authors: Zera Kristy, Bradshaw Karen, Zhu Li, Hahn Oliver, Foltz Aulden, Peterson Todd, Yousef Hanadie, Lee Davis, Mayne Elizabeth, Wyss-coray Tony, Buckwalter Marion
Keywords: Blood-brain barrier , Behavior , Cognitive impairment , Inflammation , Leukocytes
08 : 18 AM
Increased IFN-γ Levels in African American Women Following Ischemic Stroke: A Study of Ethnic Disparities in Plasma Biomarkers
Sumani Destiny, Dongarwar Deepa, El Hamamy Ahmad, Delevati Colpo Gabriela, Couture Lucy, Li Jun
Final Pr. ID: 93
Authors: Sumani Destiny, Dongarwar Deepa, El Hamamy Ahmad, Delevati Colpo Gabriela, Couture Lucy, Li Jun
Keywords: Stroke , Inflammation and inflammatory markers , Ethnicity
Hu Jinglong, Chen Yan, Xu Yun
Final Pr. ID: 95
Authors: Hu Jinglong, Chen Yan, Xu Yun
Keywords: Ischemic stroke , Neuroprotection , Inflammation
Do Trang, Couture Lucy, Guzman Gary, Delevati Colpo Gabriela, Khan Romeesa, West Bryce, Devlin Patrick, Cahuiche Ana, St Denis Anna, Roh Solji, Venna Venugopal, Mccullough Louise, Ritzel Rodney
Final Pr. ID: 91
Authors: Do Trang, Couture Lucy, Guzman Gary, Delevati Colpo Gabriela, Khan Romeesa, West Bryce, Devlin Patrick, Cahuiche Ana, St Denis Anna, Roh Solji, Venna Venugopal, Mccullough Louise, Ritzel Rodney
Keywords: Ischemic stroke , Lipids
Morais Andreia, Lynch Kirsten, Imai Takahiko, Jin Xuyan, Aykan Sanem A, Lamb Jessica, Nagarkatti Karisma, Lyden Patrick, Ayata Cenk
Final Pr. ID: 94
Authors: Morais Andreia, Lynch Kirsten, Imai Takahiko, Jin Xuyan, Aykan Sanem A, Lamb Jessica, Nagarkatti Karisma, Lyden Patrick, Ayata Cenk