American Heart Association
Genomics, Proteomics, and Transcriptomics: Unraveling the Complexities of Biological Systems
Moderated Digital Poster Session
Zone 3, Moderated Digital Poster 15
Nov 18th , 11:10 AM - 12:35 PM
11 : 10 AM
Serum Metabolomics Adds Predictive Value to Clinical and Polygenic Risk Scores for Atrial Fibrillation: A UK Biobank study of >240,000 Patients
Purkayastha Subhanik, Park Joseph, Beyer Sebastian, Lerman Bruce, Lo James, Cheung Jim
Final Pr. ID: MDP1604
Authors: Purkayastha Subhanik, Park Joseph, Beyer Sebastian, Lerman Bruce, Lo James, Cheung Jim
Keywords: Atrial fibrillation , Metabolomics , Polygenic Risk
Aggarwal Mohit, Huan Tianxiao, Courchesne Paul, Joehanes Roby, Dupuis Josee, O'connor George, Levy Daniel
Final Pr. ID: MDP1605
Authors: Aggarwal Mohit, Huan Tianxiao, Courchesne Paul, Joehanes Roby, Dupuis Josee, O'connor George, Levy Daniel
Keywords: Blood pressure , Biomarkers , Hypertension
11 : 30 AM
Transcriptomic Profiling of Human Myocardium at Sudden Death to Define Vulnerable Substrate for Lethal Arrhythmias
Caudal Arianne, Henrich Timothy, Padmanabhan Arun, Connolly Andrew, Wu Joseph, Tseng, Md Zian, Liu Yu, Pang Paul, Maison David, Nakasuka Kosuke, Feng Jean, Schwarzer-sperber Hannah Sabeth, Schwarzer Roland, Moffatt Ellen
Final Pr. ID: MDP1606
Authors: Caudal Arianne, Henrich Timothy, Padmanabhan Arun, Connolly Andrew, Wu Joseph, Tseng, Md Zian, Liu Yu, Pang Paul, Maison David, Nakasuka Kosuke, Feng Jean, Schwarzer-sperber Hannah Sabeth, Schwarzer Roland, Moffatt Ellen
Keywords: Arrhythmias , Sudden cardiac death , Transcriptomics , Fibrosis , Population science
11 : 40 AM
Proteomic biomarkers are associated with high-risk plaque phenotype and adverse events in the PROMISE trial
Karpurapu Anish, Kwee Lydia, De Calvacamp Caroline, Zhao Elizabeth, Nasir Khurram, Foldyna Borek, Douglas Pamela, Shah Svati
Final Pr. ID: MDP1607
Authors: Karpurapu Anish, Kwee Lydia, De Calvacamp Caroline, Zhao Elizabeth, Nasir Khurram, Foldyna Borek, Douglas Pamela, Shah Svati
Keywords: Atherosclerosis , Coronary artery disease , Biomarkers , Cardiac imaging , Machine Learning
11 : 50 AM
Stress-related genetic factors modify the effect of lower socioeconomic status on cardiovascular disease risk through autonomic and immune mechanisms.
Abikaram Krystel, Choi Karmel, Smoller Jordan, Seligowski Antonia, Tawakol Ahmed, Osborne Michael, Abohashem Shady, Lau Hui Chong, Khalil Maria, Aldosoky Wesam, Qamar Iqra, Civieri Giovanni, Hanlon Erin, Assefa Alula
Final Pr. ID: MDP1608
Authors: Abikaram Krystel, Choi Karmel, Smoller Jordan, Seligowski Antonia, Tawakol Ahmed, Osborne Michael, Abohashem Shady, Lau Hui Chong, Khalil Maria, Aldosoky Wesam, Qamar Iqra, Civieri Giovanni, Hanlon Erin, Assefa Alula
Keywords: Cardiology , Socioeconomic position , Gene expression , Autonomic nervous system , Inflammation and inflammatory markers
12 : 00 PM
Blood protein mediators of association between smoking and abdominal aortic aneurysm: exploration integrating human proteomic and genomic data
Yuan Shuai, Khodursky Samuel, Geng Jiawei, Sharma Pranav, Spin Joshua, Tsao Philip, Levin Michael, Damrauer Scott
Final Pr. ID: MDP1609
Authors: Yuan Shuai, Khodursky Samuel, Geng Jiawei, Sharma Pranav, Spin Joshua, Tsao Philip, Levin Michael, Damrauer Scott
Keywords: Abdominal aortic aneurysm , Smoking , Proteome , Genome-wide association studies (GWAS)
12 : 10 PM
Combining metabolomic profiling with exome sequencing in the UK Biobank to predict cardiac outcomes and interpret variants of uncertain significance in familial hypercholesterolemia
Jostins-dean Luke, Schut Kirsten, Kerminen Sini, Wurtz Peter, Barrett Jeffrey
Final Pr. ID: MDP1610
Authors: Jostins-dean Luke, Schut Kirsten, Kerminen Sini, Wurtz Peter, Barrett Jeffrey
Keywords: Hypercholesterolemia , Metabolomics , Genetics , Prediction model
Liu Yiying, Huang Rong
Final Pr. ID: MDP1611
Authors: Liu Yiying, Huang Rong
Keywords: Acute coronary syndromes , Atherosclerosis , Proteomics
12 : 00 PM
Blood protein mediators of association between smoking and abdominal aortic aneurysm: exploration integrating human proteomic and genomic data
Yuan Shuai, Khodursky Samuel, Geng Jiawei, Sharma Pranav, Spin Joshua, Tsao Philip, Levin Michael, Damrauer Scott
Final Pr. ID: MDP1609
Authors: Yuan Shuai, Khodursky Samuel, Geng Jiawei, Sharma Pranav, Spin Joshua, Tsao Philip, Levin Michael, Damrauer Scott
Keywords: Abdominal aortic aneurysm , Smoking , Proteome , Genome-wide association studies (GWAS)
12 : 10 PM
Combining metabolomic profiling with exome sequencing in the UK Biobank to predict cardiac outcomes and interpret variants of uncertain significance in familial hypercholesterolemia
Jostins-dean Luke, Schut Kirsten, Kerminen Sini, Wurtz Peter, Barrett Jeffrey
Final Pr. ID: MDP1610
Authors: Jostins-dean Luke, Schut Kirsten, Kerminen Sini, Wurtz Peter, Barrett Jeffrey
Keywords: Hypercholesterolemia , Metabolomics , Genetics , Prediction model
Aggarwal Mohit, Huan Tianxiao, Courchesne Paul, Joehanes Roby, Dupuis Josee, O'connor George, Levy Daniel
Final Pr. ID: MDP1605
Authors: Aggarwal Mohit, Huan Tianxiao, Courchesne Paul, Joehanes Roby, Dupuis Josee, O'connor George, Levy Daniel
Keywords: Blood pressure , Biomarkers , Hypertension
11 : 40 AM
Proteomic biomarkers are associated with high-risk plaque phenotype and adverse events in the PROMISE trial
Karpurapu Anish, Kwee Lydia, De Calvacamp Caroline, Zhao Elizabeth, Nasir Khurram, Foldyna Borek, Douglas Pamela, Shah Svati
Final Pr. ID: MDP1607
Authors: Karpurapu Anish, Kwee Lydia, De Calvacamp Caroline, Zhao Elizabeth, Nasir Khurram, Foldyna Borek, Douglas Pamela, Shah Svati
Keywords: Atherosclerosis , Coronary artery disease , Biomarkers , Cardiac imaging , Machine Learning
Liu Yiying, Huang Rong
Final Pr. ID: MDP1611
Authors: Liu Yiying, Huang Rong
Keywords: Acute coronary syndromes , Atherosclerosis , Proteomics
11 : 10 AM
Serum Metabolomics Adds Predictive Value to Clinical and Polygenic Risk Scores for Atrial Fibrillation: A UK Biobank study of >240,000 Patients
Purkayastha Subhanik, Park Joseph, Beyer Sebastian, Lerman Bruce, Lo James, Cheung Jim
Final Pr. ID: MDP1604
Authors: Purkayastha Subhanik, Park Joseph, Beyer Sebastian, Lerman Bruce, Lo James, Cheung Jim
Keywords: Atrial fibrillation , Metabolomics , Polygenic Risk
11 : 50 AM
Stress-related genetic factors modify the effect of lower socioeconomic status on cardiovascular disease risk through autonomic and immune mechanisms.
Abikaram Krystel, Choi Karmel, Smoller Jordan, Seligowski Antonia, Tawakol Ahmed, Osborne Michael, Abohashem Shady, Lau Hui Chong, Khalil Maria, Aldosoky Wesam, Qamar Iqra, Civieri Giovanni, Hanlon Erin, Assefa Alula
Final Pr. ID: MDP1608
Authors: Abikaram Krystel, Choi Karmel, Smoller Jordan, Seligowski Antonia, Tawakol Ahmed, Osborne Michael, Abohashem Shady, Lau Hui Chong, Khalil Maria, Aldosoky Wesam, Qamar Iqra, Civieri Giovanni, Hanlon Erin, Assefa Alula
Keywords: Cardiology , Socioeconomic position , Gene expression , Autonomic nervous system , Inflammation and inflammatory markers
11 : 30 AM
Transcriptomic Profiling of Human Myocardium at Sudden Death to Define Vulnerable Substrate for Lethal Arrhythmias
Caudal Arianne, Henrich Timothy, Padmanabhan Arun, Connolly Andrew, Wu Joseph, Tseng, Md Zian, Liu Yu, Pang Paul, Maison David, Nakasuka Kosuke, Feng Jean, Schwarzer-sperber Hannah Sabeth, Schwarzer Roland, Moffatt Ellen
Final Pr. ID: MDP1606
Authors: Caudal Arianne, Henrich Timothy, Padmanabhan Arun, Connolly Andrew, Wu Joseph, Tseng, Md Zian, Liu Yu, Pang Paul, Maison David, Nakasuka Kosuke, Feng Jean, Schwarzer-sperber Hannah Sabeth, Schwarzer Roland, Moffatt Ellen
Keywords: Arrhythmias , Sudden cardiac death , Transcriptomics , Fibrosis , Population science