American Heart Association
Genomic and Precision Medicine Early Career Investigator Award Competition
Abstract Oral Session
S103A
Nov 16th , 01:30 PM - 02:45 PM
01 : 30 PM
Coronary Artery Disease Polygenic Risk Scores with Equivalent Performance Produce Discordant Estimates of Individual Risk
Abramowitz Sarah, Voight Benjamin, Pasaniuc Bogdan, Levin Michael, Damrauer Scott, Boulier Kristin, Keat Karl, Cardone Katie, Shivakumar Manu, Depaolo John, Judy Renae, Kim Dokyoon, Ritchie Marylyn
Final Pr. ID: 4141151
Authors: Abramowitz Sarah, Voight Benjamin, Pasaniuc Bogdan, Levin Michael, Damrauer Scott, Boulier Kristin, Keat Karl, Cardone Katie, Shivakumar Manu, Depaolo John, Judy Renae, Kim Dokyoon, Ritchie Marylyn
Keywords: Polygenic Risk , Coronary artery disease , Genomics
Curran Lara, Halliday Brian, Tayal Upasana, De Marvao Antonio, Ware James, Prasad Sanjay, O'regan Declan, Inglese Paolo, Rjoob Khaled, Mcgurk Kathryn, Lu Chang, Zheng Sean, Tahasildar Shamin, Kalaie Soodeh, Bai Wenjia
Final Pr. ID: 4119052
Authors: Curran Lara, Halliday Brian, Tayal Upasana, De Marvao Antonio, Ware James, Prasad Sanjay, O'regan Declan, Inglese Paolo, Rjoob Khaled, Mcgurk Kathryn, Lu Chang, Zheng Sean, Tahasildar Shamin, Kalaie Soodeh, Bai Wenjia
Keywords: Precision medicine , Cardiac MRI , Machine Learning , Cardiomyopathy , Genomics
02 : 00 PM
Employing Bioinformatic Tools to Identify High-Risk Variants of Unknown Significance in Aortopathy Genes Associated with Aortic Dissection
Depaolo John, Bamshad Michael, Damrauer Scott, Milewicz Dianna, Guo Dongchuan, Murdock David, Cecchi Alana, Lemaire Scott, Shen Ying, Estrera Anthony, Coselli Joseph, Smith Joshua D.
Final Pr. ID: 4138455
Authors: Depaolo John, Bamshad Michael, Damrauer Scott, Milewicz Dianna, Guo Dongchuan, Murdock David, Cecchi Alana, Lemaire Scott, Shen Ying, Estrera Anthony, Coselli Joseph, Smith Joshua D.
Keywords: Thoracic Aorta , Aneurysms , Dissection , Genetic testing , Risk Factors
02 : 15 PM
Genome wide association study meta-analysis of 19,487 individuals with mitral valve prolapse identifies 52 novel genomic regions and highlights pro-fibrosis genes
Small Aeron, Wells Quinn, Wilson Peter, Cho Kelly, Rader Daniel, Ganna Andrea, Helgadottir Anna, Holm Hilma, Stefansson Kari, Gudbjartsson Daniel, Vy Ha My, Berrandou Takiy-eddine, Rosenberg Michael, Milan David, Borger Michael, Dieterlen Maja-theresa, Kontorovich Amy, Engert Jamie, Thanassoulis George, Farber-eger Eric, Gignoux Christopher, Ellinor Patrick, Georges Adrien, Peloso Gina, Norris Russell, Yu Mengyao, Bouatia-naji Nabila, Natarajan Pradeep, Morningstar Jordan, Huff Matthew, Yang Ta-yu, Lee Jiwoo, Abner Erik, Bundgaard Henning
Final Pr. ID: 4143772
Authors: Small Aeron, Wells Quinn, Wilson Peter, Cho Kelly, Rader Daniel, Ganna Andrea, Helgadottir Anna, Holm Hilma, Stefansson Kari, Gudbjartsson Daniel, Vy Ha My, Berrandou Takiy-eddine, Rosenberg Michael, Milan David, Borger Michael, Dieterlen Maja-theresa, Kontorovich Amy, Engert Jamie, Thanassoulis George, Farber-eger Eric, Gignoux Christopher, Ellinor Patrick, Georges Adrien, Peloso Gina, Norris Russell, Yu Mengyao, Bouatia-naji Nabila, Natarajan Pradeep, Morningstar Jordan, Huff Matthew, Yang Ta-yu, Lee Jiwoo, Abner Erik, Bundgaard Henning
Keywords: Mitral valve disease , Genome-wide association studies (GWAS) , Fibrosis
02 : 30 PM
Aladyn Individual: Dynamic Individual Comorbidity Modeling for Genomic Discovery and Clinical Prediction
Urbut Sarah, Natarajan Pradeep, Ding Yi, Taraszka Kodi, Yeung Ming Wai, Patel Aniruddh, Hornsby Whitney, Duan Rui, Gusev Alexander, Parmigiani Giovanni
Final Pr. ID: 4125887
Authors: Urbut Sarah, Natarajan Pradeep, Ding Yi, Taraszka Kodi, Yeung Ming Wai, Patel Aniruddh, Hornsby Whitney, Duan Rui, Gusev Alexander, Parmigiani Giovanni
Keywords: Genetics , Prevention , Precision medicine , Epidemiologic methods
02 : 30 PM
Aladyn Individual: Dynamic Individual Comorbidity Modeling for Genomic Discovery and Clinical Prediction
Urbut Sarah, Natarajan Pradeep, Ding Yi, Taraszka Kodi, Yeung Ming Wai, Patel Aniruddh, Hornsby Whitney, Duan Rui, Gusev Alexander, Parmigiani Giovanni
Final Pr. ID: 4125887
Authors: Urbut Sarah, Natarajan Pradeep, Ding Yi, Taraszka Kodi, Yeung Ming Wai, Patel Aniruddh, Hornsby Whitney, Duan Rui, Gusev Alexander, Parmigiani Giovanni
Keywords: Genetics , Prevention , Precision medicine , Epidemiologic methods
01 : 30 PM
Coronary Artery Disease Polygenic Risk Scores with Equivalent Performance Produce Discordant Estimates of Individual Risk
Abramowitz Sarah, Voight Benjamin, Pasaniuc Bogdan, Levin Michael, Damrauer Scott, Boulier Kristin, Keat Karl, Cardone Katie, Shivakumar Manu, Depaolo John, Judy Renae, Kim Dokyoon, Ritchie Marylyn
Final Pr. ID: 4141151
Authors: Abramowitz Sarah, Voight Benjamin, Pasaniuc Bogdan, Levin Michael, Damrauer Scott, Boulier Kristin, Keat Karl, Cardone Katie, Shivakumar Manu, Depaolo John, Judy Renae, Kim Dokyoon, Ritchie Marylyn
Keywords: Polygenic Risk , Coronary artery disease , Genomics
02 : 00 PM
Employing Bioinformatic Tools to Identify High-Risk Variants of Unknown Significance in Aortopathy Genes Associated with Aortic Dissection
Depaolo John, Bamshad Michael, Damrauer Scott, Milewicz Dianna, Guo Dongchuan, Murdock David, Cecchi Alana, Lemaire Scott, Shen Ying, Estrera Anthony, Coselli Joseph, Smith Joshua D.
Final Pr. ID: 4138455
Authors: Depaolo John, Bamshad Michael, Damrauer Scott, Milewicz Dianna, Guo Dongchuan, Murdock David, Cecchi Alana, Lemaire Scott, Shen Ying, Estrera Anthony, Coselli Joseph, Smith Joshua D.
Keywords: Thoracic Aorta , Aneurysms , Dissection , Genetic testing , Risk Factors
02 : 15 PM
Genome wide association study meta-analysis of 19,487 individuals with mitral valve prolapse identifies 52 novel genomic regions and highlights pro-fibrosis genes
Small Aeron, Wells Quinn, Wilson Peter, Cho Kelly, Rader Daniel, Ganna Andrea, Helgadottir Anna, Holm Hilma, Stefansson Kari, Gudbjartsson Daniel, Vy Ha My, Berrandou Takiy-eddine, Rosenberg Michael, Milan David, Borger Michael, Dieterlen Maja-theresa, Kontorovich Amy, Engert Jamie, Thanassoulis George, Farber-eger Eric, Gignoux Christopher, Ellinor Patrick, Georges Adrien, Peloso Gina, Norris Russell, Yu Mengyao, Bouatia-naji Nabila, Natarajan Pradeep, Morningstar Jordan, Huff Matthew, Yang Ta-yu, Lee Jiwoo, Abner Erik, Bundgaard Henning
Final Pr. ID: 4143772
Authors: Small Aeron, Wells Quinn, Wilson Peter, Cho Kelly, Rader Daniel, Ganna Andrea, Helgadottir Anna, Holm Hilma, Stefansson Kari, Gudbjartsson Daniel, Vy Ha My, Berrandou Takiy-eddine, Rosenberg Michael, Milan David, Borger Michael, Dieterlen Maja-theresa, Kontorovich Amy, Engert Jamie, Thanassoulis George, Farber-eger Eric, Gignoux Christopher, Ellinor Patrick, Georges Adrien, Peloso Gina, Norris Russell, Yu Mengyao, Bouatia-naji Nabila, Natarajan Pradeep, Morningstar Jordan, Huff Matthew, Yang Ta-yu, Lee Jiwoo, Abner Erik, Bundgaard Henning
Keywords: Mitral valve disease , Genome-wide association studies (GWAS) , Fibrosis
Curran Lara, Halliday Brian, Tayal Upasana, De Marvao Antonio, Ware James, Prasad Sanjay, O'regan Declan, Inglese Paolo, Rjoob Khaled, Mcgurk Kathryn, Lu Chang, Zheng Sean, Tahasildar Shamin, Kalaie Soodeh, Bai Wenjia
Final Pr. ID: 4119052
Authors: Curran Lara, Halliday Brian, Tayal Upasana, De Marvao Antonio, Ware James, Prasad Sanjay, O'regan Declan, Inglese Paolo, Rjoob Khaled, Mcgurk Kathryn, Lu Chang, Zheng Sean, Tahasildar Shamin, Kalaie Soodeh, Bai Wenjia
Keywords: Precision medicine , Cardiac MRI , Machine Learning , Cardiomyopathy , Genomics