Logo

American Heart Association

  2
  0


Final ID: Sa3077

Trends in Atrial Fibrillation/Flutter and Dementia–Related Mortality in the United States from 1999-2020

Abstract Body (Do not enter title and authors here): Background
Emerging evidence suggests a potential link between atrial fibrillation and dementia, yet mortality data for patients with both conditions remain sparse. This study aims to investigate the trends in mortality associated with atrial fibrillation/flutter and dementia in the United States over a two-decade period.

Methods
Utilizing the Centers for Disease Control and Prevention's Wide-ranging Online Data for Epidemiologic Research database, we identified individuals aged 55 and above who had both atrial fibrillation/flutter and dementia listed as either an underlying or contributing cause of death. We calculated age-adjusted mortality rates (AAMR) per 100,000 individuals and annual percent change (APC). Analysis is stratified by gender, race/ethnicity, and geographic region.

Results
Between 1999 and 2020, there were 417,172 deaths associated with both atrial fibrillation/flutter and dementia. The overall AAMR surged from 10.12 in 1999 to 44.16 in 2020 (APC: 6.7 [95% CI, 6.15-7.44], p-trend<.001), a rise observed consistently across gender, race, and region. Men exhibited a higher AAMR than women (26.6 vs 25.9). Among racial groups, non-Hispanic White individuals had a higher AAMR compared to non-Hispanic Black individuals (28.71 vs 16.02). Geographically, the Western U.S. recorded the highest AAMR (28.88 [95% CI, 28.69-29.06]), while the Midwest experienced the most significant APC increase (3.89 [95% CI, 2.56-6.12]).

Conclusion
There has been a significant and steady rise in mortality rates associated with atrial fibrillation/flutter and dementia, affecting all genders and racial groups. This alarming trend highlights the urgent need for specialized interventions to mitigate this escalating public health issue.
  • Chia, Jia Ee  ( International Medical University , Kuala Lumpur , Malaysia )
  • Ang, Song Peng  ( Rutgers Health CMC , Toms River , New Jersey , United States )
  • Jaiswal, Vikash  ( JCCR Cardiology Research , Jaunpur , India )
  • Usman, Mohammed Haris  ( RWJ Barnabas Health System , Princeton , New Jersey , United States )
  • Lee, Kwan  ( Mayo Clinic Arizona , Scottsdale , Arizona , United States )
  • Author Disclosures:
    Jia Ee Chia: DO NOT have relevant financial relationships | Song Peng Ang: DO NOT have relevant financial relationships | Vikash Jaiswal: DO NOT have relevant financial relationships | Mohammed Haris Usman: DO NOT have relevant financial relationships | Kwan Lee: DO NOT have relevant financial relationships
Meeting Info:

Scientific Sessions 2024

2024

Chicago, Illinois

Session Info:

CVD Science Smorgasbord II

Saturday, 11/16/2024 , 10:30AM - 11:30AM

Abstract Poster Session

More abstracts on this topic:
Age-related Differences in Peak Oxygen Uptake in Patients with Multimorbidity Undergoing Cardiac Rehabilitation

Gomes Pauline, Miller Sophie, Chacin-suarez Audry, Olson Thomas

A pharmacovigilance investigation from the FAERS database on patients using pembrolizumab and its association with cardiac arrhythmias

Upreti Prakash, Jancic Predrag, Milutinovic Stefan, Rathore Azeem, Nassar Sameh, Karki Roshan, Rao Mohan, Patel Brijesh

More abstracts from these authors:
Trends, Outcomes and Predictors of Mortality in Patients with Myeloproliferative Neoplasms Undergoing Percutaneous Coronary Intervention: Insights from National Database

Ang Song Peng, Chia Jia Ee, Krittanawong Chayakrit, Misra Kanchan, Jaiswal Vikash, Song David, Usman Mohammed Haris, Piana Robert, Mukherjee Debabrata

Trends and Sociodemographic Disparities in Cardiovascular Mortality Among People Living with HIV: A Retrospective Analysis from 1999 to 2020

Ang Song Peng, Chia Jia Ee, Iglesias Jose, Lee Kwan

You have to be authorized to contact abstract author. Please, Login
Not Available