American Heart Association
The Next Frontier: Novel Molecular Mechanisms of Pulmonary Hypertension
Moderated Digital Poster Session
Zone 4, Moderated Digital Poster 17
Nov 18th , 09:30 AM - 11:00 AM
09 : 30 AM
C-C motif chemokine receptor-2 disruption Synergizes with Phosphodiesterase Type 5 Inhibition in Ameliorating Pulmonary Hypertension in Monocrotaline-treated Rats: Proof-of-Concept Study for a Combination therapy and Potential Mechanisms
Tsuboya Naoki, Mitani Yoshihide, Sawada Hirofumi, Takeoka Mami, Ohya Kazunobu, Oshita Hironori, Yodoya Noriko, Ohashi Hiroyuki, Maruyama Junko, Okamoto Ryuji, Mashimo Tomoji, Dohi Kaoru, Nishimura Yuhei, Maruyama Kazuo, Hirayama Masahiro
Final Pr. ID: MDP1644
Authors: Tsuboya Naoki, Mitani Yoshihide, Sawada Hirofumi, Takeoka Mami, Ohya Kazunobu, Oshita Hironori, Yodoya Noriko, Ohashi Hiroyuki, Maruyama Junko, Okamoto Ryuji, Mashimo Tomoji, Dohi Kaoru, Nishimura Yuhei, Maruyama Kazuo, Hirayama Masahiro
Keywords: Pulmonary hypertension , Inflammation and inflammatory markers , Pulmonary circulation
09 : 40 AM
Targeting Aurora Kinase B Improves Vascular Remodeling in Pulmonary Arterial Hypertension
Lemay Sarah-eve, Mougin Manon, Sauvaget Melanie, Reem El-kabbout, Valasarajan Chanil, Yamamoto Keiko, Martineau Sandra, Pelletier Andreanne, Grobs Yann, Bourgeois Alice, Romanet Charlotte, Breuils Bonnet Sandra, Montesinos Monica, Lu Min, Chen Huidong, Theberge Charlie, Potus Francois, Savai Pullamsetti Soni, Provencher Steeve, Bonnet Sebastien, Boucherat Olivier
Final Pr. ID: MDP1645
Authors: Lemay Sarah-eve, Mougin Manon, Sauvaget Melanie, Reem El-kabbout, Valasarajan Chanil, Yamamoto Keiko, Martineau Sandra, Pelletier Andreanne, Grobs Yann, Bourgeois Alice, Romanet Charlotte, Breuils Bonnet Sandra, Montesinos Monica, Lu Min, Chen Huidong, Theberge Charlie, Potus Francois, Savai Pullamsetti Soni, Provencher Steeve, Bonnet Sebastien, Boucherat Olivier
Keywords: Pulmonary hypertension
09 : 50 AM
Treatment of pulmonary arterial hypertension by blocking integrin a5b1, a potential disease-modifying strategy
Montesinos Monica, Lemay Sarah-eve, Kapoor Parmita, Rapisardi Hailey, Nguyen Minh Hai, Kim Haejin, Akram Muzaffar, Jain Dhawal, Konopka Elizabeth, Moy Terence I., Smukste Inese, Mcteague T. Andrew, Dowling James, Lama Sujan, Pondish Jessica, Qiao Qi, Monroy Meghan Monroy, Lin Albert, Wang Hua, Boucherat Olivier, Sauvaget Melanie, Potus Francois, Breuils Bonnet Sandra, Theberge Charlie, Provencher Steeve, Ray Adrian, Lippa Blaise, Bonnet Sebastien, Goodwin Bryan, Lu Min
Final Pr. ID: MDP1646
Authors: Montesinos Monica, Lemay Sarah-eve, Kapoor Parmita, Rapisardi Hailey, Nguyen Minh Hai, Kim Haejin, Akram Muzaffar, Jain Dhawal, Konopka Elizabeth, Moy Terence I., Smukste Inese, Mcteague T. Andrew, Dowling James, Lama Sujan, Pondish Jessica, Qiao Qi, Monroy Meghan Monroy, Lin Albert, Wang Hua, Boucherat Olivier, Sauvaget Melanie, Potus Francois, Breuils Bonnet Sandra, Theberge Charlie, Provencher Steeve, Ray Adrian, Lippa Blaise, Bonnet Sebastien, Goodwin Bryan, Lu Min
Keywords: Vascular disease , Pulmonary hypertension , Remodeling
10 : 00 AM
Interleukin-22 Prevents Right Ventricular Remodeling and Tricuspid Regurgitation during Pressure Overload through a Unique Mechanism
Shibao Kodai, Yasukawa Hideo, Akagaki Daiki, Okabe Kota, Yanai Toshiyuki, Shima Kanako, Yamamoto Mai, Fukumoto Yoshihiro
Final Pr. ID: MDP1647
Authors: Shibao Kodai, Yasukawa Hideo, Akagaki Daiki, Okabe Kota, Yanai Toshiyuki, Shima Kanako, Yamamoto Mai, Fukumoto Yoshihiro
Keywords: Right Ventricular Dysfunction , Pulmonary hypertension , Molecular
10 : 10 AM
Transcription factor LITAF orchestrates pericyte-mediated vascular inflammation via modulation of protein trafficking pathways in pulmonary hypertension
Chelladurai Prakash, Condon David, Agarwal Stuti, Mitra Ankita, Shamskhou Kian, Nathan Abinaya, Sweatt Andrew, Chakraborty Ananya, Zamanian Roham, Yuan Ke, Dejesus Vinicio
Final Pr. ID: MDP1648
Authors: Chelladurai Prakash, Condon David, Agarwal Stuti, Mitra Ankita, Shamskhou Kian, Nathan Abinaya, Sweatt Andrew, Chakraborty Ananya, Zamanian Roham, Yuan Ke, Dejesus Vinicio
Keywords: Vascular disease , Pulmonary circulation , Inflammation and inflammatory markers , Targeted therapeutics , Epigenetics
10 : 20 AM
SOX17 Deficiency is Additive to High Shear Stress in Reducing Endothelial Genes Linked to BMPR2 and NOTCH and Promoting Inflammation in Pulmonary Arterial Hypertension
Zhang Chongyang, Shinohara Tsutomu, Lee-yow Yannick, Guo Kathrine, Lago-docampo Mauro, Engreitz Jesse, Rabinovitch Marlene
Final Pr. ID: MDP1649
Authors: Zhang Chongyang, Shinohara Tsutomu, Lee-yow Yannick, Guo Kathrine, Lago-docampo Mauro, Engreitz Jesse, Rabinovitch Marlene
Keywords: Pulmonary artery , Pulmonary hypertension , Endothelial function
10 : 30 AM
Reduced BMPR2 in Monocytes De-represses HERV-K and Sustains Inflammation in Pulmonary Arterial Hypertension
Adil Mir, Cao Aiqin, Lago-docampo Mauro, Zhang Chongyang, Rabinovitch Marlene
Final Pr. ID: MDP1650
Authors: Adil Mir, Cao Aiqin, Lago-docampo Mauro, Zhang Chongyang, Rabinovitch Marlene
Keywords: Inflammation , Blood cells , Cell signaling , Immune system , Gene expression
10 : 40 AM
Targeting Hepatic Complement C3 Attenuates Pulmonary Arterial Hypertension Phenotype in Rodents
Keles Merve, Arnold Nadine, West Laura, Turton Helena, Kim Sung-kwon, Lasaro Melissa, Rammanujam Meera, Chang C-hong, Wilkins M, Lawrie Allan
Final Pr. ID: MDP1651
Authors: Keles Merve, Arnold Nadine, West Laura, Turton Helena, Kim Sung-kwon, Lasaro Melissa, Rammanujam Meera, Chang C-hong, Wilkins M, Lawrie Allan
Keywords: Pulmonary hypertension , Pulmonary circulation
09 : 30 AM
C-C motif chemokine receptor-2 disruption Synergizes with Phosphodiesterase Type 5 Inhibition in Ameliorating Pulmonary Hypertension in Monocrotaline-treated Rats: Proof-of-Concept Study for a Combination therapy and Potential Mechanisms
Tsuboya Naoki, Mitani Yoshihide, Sawada Hirofumi, Takeoka Mami, Ohya Kazunobu, Oshita Hironori, Yodoya Noriko, Ohashi Hiroyuki, Maruyama Junko, Okamoto Ryuji, Mashimo Tomoji, Dohi Kaoru, Nishimura Yuhei, Maruyama Kazuo, Hirayama Masahiro
Final Pr. ID: MDP1644
Authors: Tsuboya Naoki, Mitani Yoshihide, Sawada Hirofumi, Takeoka Mami, Ohya Kazunobu, Oshita Hironori, Yodoya Noriko, Ohashi Hiroyuki, Maruyama Junko, Okamoto Ryuji, Mashimo Tomoji, Dohi Kaoru, Nishimura Yuhei, Maruyama Kazuo, Hirayama Masahiro
Keywords: Pulmonary hypertension , Inflammation and inflammatory markers , Pulmonary circulation
10 : 00 AM
Interleukin-22 Prevents Right Ventricular Remodeling and Tricuspid Regurgitation during Pressure Overload through a Unique Mechanism
Shibao Kodai, Yasukawa Hideo, Akagaki Daiki, Okabe Kota, Yanai Toshiyuki, Shima Kanako, Yamamoto Mai, Fukumoto Yoshihiro
Final Pr. ID: MDP1647
Authors: Shibao Kodai, Yasukawa Hideo, Akagaki Daiki, Okabe Kota, Yanai Toshiyuki, Shima Kanako, Yamamoto Mai, Fukumoto Yoshihiro
Keywords: Right Ventricular Dysfunction , Pulmonary hypertension , Molecular
10 : 30 AM
Reduced BMPR2 in Monocytes De-represses HERV-K and Sustains Inflammation in Pulmonary Arterial Hypertension
Adil Mir, Cao Aiqin, Lago-docampo Mauro, Zhang Chongyang, Rabinovitch Marlene
Final Pr. ID: MDP1650
Authors: Adil Mir, Cao Aiqin, Lago-docampo Mauro, Zhang Chongyang, Rabinovitch Marlene
Keywords: Inflammation , Blood cells , Cell signaling , Immune system , Gene expression
10 : 20 AM
SOX17 Deficiency is Additive to High Shear Stress in Reducing Endothelial Genes Linked to BMPR2 and NOTCH and Promoting Inflammation in Pulmonary Arterial Hypertension
Zhang Chongyang, Shinohara Tsutomu, Lee-yow Yannick, Guo Kathrine, Lago-docampo Mauro, Engreitz Jesse, Rabinovitch Marlene
Final Pr. ID: MDP1649
Authors: Zhang Chongyang, Shinohara Tsutomu, Lee-yow Yannick, Guo Kathrine, Lago-docampo Mauro, Engreitz Jesse, Rabinovitch Marlene
Keywords: Pulmonary artery , Pulmonary hypertension , Endothelial function
09 : 40 AM
Targeting Aurora Kinase B Improves Vascular Remodeling in Pulmonary Arterial Hypertension
Lemay Sarah-eve, Mougin Manon, Sauvaget Melanie, Reem El-kabbout, Valasarajan Chanil, Yamamoto Keiko, Martineau Sandra, Pelletier Andreanne, Grobs Yann, Bourgeois Alice, Romanet Charlotte, Breuils Bonnet Sandra, Montesinos Monica, Lu Min, Chen Huidong, Theberge Charlie, Potus Francois, Savai Pullamsetti Soni, Provencher Steeve, Bonnet Sebastien, Boucherat Olivier
Final Pr. ID: MDP1645
Authors: Lemay Sarah-eve, Mougin Manon, Sauvaget Melanie, Reem El-kabbout, Valasarajan Chanil, Yamamoto Keiko, Martineau Sandra, Pelletier Andreanne, Grobs Yann, Bourgeois Alice, Romanet Charlotte, Breuils Bonnet Sandra, Montesinos Monica, Lu Min, Chen Huidong, Theberge Charlie, Potus Francois, Savai Pullamsetti Soni, Provencher Steeve, Bonnet Sebastien, Boucherat Olivier
Keywords: Pulmonary hypertension
10 : 40 AM
Targeting Hepatic Complement C3 Attenuates Pulmonary Arterial Hypertension Phenotype in Rodents
Keles Merve, Arnold Nadine, West Laura, Turton Helena, Kim Sung-kwon, Lasaro Melissa, Rammanujam Meera, Chang C-hong, Wilkins M, Lawrie Allan
Final Pr. ID: MDP1651
Authors: Keles Merve, Arnold Nadine, West Laura, Turton Helena, Kim Sung-kwon, Lasaro Melissa, Rammanujam Meera, Chang C-hong, Wilkins M, Lawrie Allan
Keywords: Pulmonary hypertension , Pulmonary circulation
10 : 10 AM
Transcription factor LITAF orchestrates pericyte-mediated vascular inflammation via modulation of protein trafficking pathways in pulmonary hypertension
Chelladurai Prakash, Condon David, Agarwal Stuti, Mitra Ankita, Shamskhou Kian, Nathan Abinaya, Sweatt Andrew, Chakraborty Ananya, Zamanian Roham, Yuan Ke, Dejesus Vinicio
Final Pr. ID: MDP1648
Authors: Chelladurai Prakash, Condon David, Agarwal Stuti, Mitra Ankita, Shamskhou Kian, Nathan Abinaya, Sweatt Andrew, Chakraborty Ananya, Zamanian Roham, Yuan Ke, Dejesus Vinicio
Keywords: Vascular disease , Pulmonary circulation , Inflammation and inflammatory markers , Targeted therapeutics , Epigenetics
09 : 50 AM
Treatment of pulmonary arterial hypertension by blocking integrin a5b1, a potential disease-modifying strategy
Montesinos Monica, Lemay Sarah-eve, Kapoor Parmita, Rapisardi Hailey, Nguyen Minh Hai, Kim Haejin, Akram Muzaffar, Jain Dhawal, Konopka Elizabeth, Moy Terence I., Smukste Inese, Mcteague T. Andrew, Dowling James, Lama Sujan, Pondish Jessica, Qiao Qi, Monroy Meghan Monroy, Lin Albert, Wang Hua, Boucherat Olivier, Sauvaget Melanie, Potus Francois, Breuils Bonnet Sandra, Theberge Charlie, Provencher Steeve, Ray Adrian, Lippa Blaise, Bonnet Sebastien, Goodwin Bryan, Lu Min
Final Pr. ID: MDP1646
Authors: Montesinos Monica, Lemay Sarah-eve, Kapoor Parmita, Rapisardi Hailey, Nguyen Minh Hai, Kim Haejin, Akram Muzaffar, Jain Dhawal, Konopka Elizabeth, Moy Terence I., Smukste Inese, Mcteague T. Andrew, Dowling James, Lama Sujan, Pondish Jessica, Qiao Qi, Monroy Meghan Monroy, Lin Albert, Wang Hua, Boucherat Olivier, Sauvaget Melanie, Potus Francois, Breuils Bonnet Sandra, Theberge Charlie, Provencher Steeve, Ray Adrian, Lippa Blaise, Bonnet Sebastien, Goodwin Bryan, Lu Min
Keywords: Vascular disease , Pulmonary hypertension , Remodeling