Showing Results from 1 to 12 of 200.
03 : 30 PM
A Cross-scale Causal Machine Learning Framework Pinpoints Mgl2+ Macrophage Orchestrators of Balanced Arterial Growth
Han Jonghyeuk, Kong Dasom, Schwarz Erica, Takaesu Felipe, Humphrey Jay, Park Hyun-ji, Davis Michael E
Final Pr. ID: 4364135
Authors: Han Jonghyeuk, Kong Dasom, Schwarz Erica, Takaesu Felipe, Humphrey Jay, Park Hyun-ji, Davis Michael E
Keywords: Arteriogenesis, Pulmonary artery, Artificial Intelligence, Machine Learning, Systems biology
09 : 43 AM
A "non-muscle" alpha-actinin is an intrinsic component of the cardiac Z-disc and regulates sarcomere turnover, contractility, and heart remodeling
Hayes James, Ritter Dylan, Neininger-castro Abigail, Willet Alaina, Caplan Leah, Wang Yu, Liu Xiao, Taneja Nilay, Sanchez Zachary, Smart Kyra, Choudhary Dharmendra, Reinhart-king Cynthia, Liu Qi, Tyska Matthew, Tabdanov Erdem, Wells Quinn, Knapik Ela, Burnette Dylan
Final Pr. ID: MP2709
Authors: Hayes James, Ritter Dylan, Neininger-castro Abigail, Willet Alaina, Caplan Leah, Wang Yu, Liu Xiao, Taneja Nilay, Sanchez Zachary, Smart Kyra, Choudhary Dharmendra, Reinhart-king Cynthia, Liu Qi, Tyska Matthew, Tabdanov Erdem, Wells Quinn, Knapik Ela, Burnette Dylan
Keywords: Contractility, Hypertrophy, Remodeling, Cells, Molecular biology
12 : 29 PM
A Suppression-and-Replacement Platform Identifies Pathogenic Variants in the LMNA-Encoded Lamin A/C Ig-Like Domain as Drivers of Nuclear Distortion and Aggregation
Huynh Trung, Kim Changsung, Tester David, Castrichini Matteo, Giudicessi John, Ackerman Michael
Final Pr. ID: MP2727
Authors: Huynh Trung, Kim Changsung, Tester David, Castrichini Matteo, Giudicessi John, Ackerman Michael
Keywords: Cardiomyopathy, Gene mutations, Genetic techniques, Stem cell biology
01 : 30 PM
A Synthetic Small Molecule Efficiently Sequesters Carbon Monoxide from Hemoglobin and Red Blood Cells In Vitro
Correnti Jacob, Ai Yong, Gladwin Mark, Xue Fengtian, Rose Jason, Demartino Anthony
Final Pr. ID: Sun1004
Authors: Correnti Jacob, Ai Yong, Gladwin Mark, Xue Fengtian, Rose Jason, Demartino Anthony
Keywords: Hemoglobin, Molecular biology, Cardiovascular therapeutics, Oxygen uptake, New technology
04 : 30 PM
AAV9-Mediated Overexpression of Mixed Lineage Kinase 3 After Transaortic Constriction Improves Left Ventricular Function
Pande Suchita, Martin Gregory, Blanton Robert
Final Pr. ID: We109
Authors: Pande Suchita, Martin Gregory, Blanton Robert
Keywords: Heart failure, Cardiac hypertrophy, Molecular biology, Signal transduction
04 : 10 PM
ALOX15 mediates thrombin-induced myristoylation, trafficking and interaction of PARs leading to platelet activation and hemostasis
Govatati Suresh, Hoque Md Monirul, Thota Swapna, Rao Gadiparthi
Final Pr. ID: 4343268
Authors: Govatati Suresh, Hoque Md Monirul, Thota Swapna, Rao Gadiparthi
Keywords: Hemostasis, Platelet receptor blockers, Lipids, Thrombin, Molecular biology
10 : 45 AM
An Unusual but Clinically Significant Mechanism of Cerebral Fat Embolism Syndrome in Sickle Cell Disease Patient via Patent Foramen Ovale
Obeng Samed, Odukudu God-dowell, Amadi Chima, Ford Dimitri, Azees Ridwan, Saint Julien Berlandson, Opare-addo Michael S. N.
Final Pr. ID: MP2096
Authors: Obeng Samed, Odukudu God-dowell, Amadi Chima, Ford Dimitri, Azees Ridwan, Saint Julien Berlandson, Opare-addo Michael S. N.
Keywords: Cerebrovascular circulation, Echocardiography, Magnetic resonance neuroimaging, Structural heart disease intervention, Biology, developmental
04 : 30 PM
ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart
Liu Shijie, Gao Yaqi, Kim Kyoungmin, Gammon Seth, Tan Lin, Pham Janet, Khanna Radhika, Gould Benjamin, Salazar Rebecca, Lien Evan, Hanson Blake, Vander Heiden Matthew, Lorenzi Philip, Taegtmeyer Heinrich, Piwnica-worms David, Martin James, Karlstaedt Anja
Final Pr. ID: Mo026
Authors: Liu Shijie, Gao Yaqi, Kim Kyoungmin, Gammon Seth, Tan Lin, Pham Janet, Khanna Radhika, Gould Benjamin, Salazar Rebecca, Lien Evan, Hanson Blake, Vander Heiden Matthew, Lorenzi Philip, Taegtmeyer Heinrich, Piwnica-worms David, Martin James, Karlstaedt Anja
Keywords: Cardiomyopathy, Systems biology, Metabolism, Metabolomics
Rendon C. Javier, Lefkowitz Rebecca, Garver Hannah, Lauver Adam, Fink Gregory, Krieger-burke Teresa, Watts Stephanie, Contreras Andres
Final Pr. ID: 021
Authors: Rendon C. Javier, Lefkowitz Rebecca, Garver Hannah, Lauver Adam, Fink Gregory, Krieger-burke Teresa, Watts Stephanie, Contreras Andres
Keywords: Hypertension: experimental, Stem cell biology, Fibrosis, Collagen, Pathology
12 : 32 PM
Brain-Derived Exosomal Biomarkers of Neuroinflammation and Brain Iron Deficiency in Infants with Critical Congenital Heart Disease: A Pilot Study
Elgersma Kristin, Maxim Zia, Munirathinam Manjula, Peyvandi Shabnam, Seed Mike, Mital Seema, Georgieff Michael, Tran Phu
Final Pr. ID: MP1607
Authors: Elgersma Kristin, Maxim Zia, Munirathinam Manjula, Peyvandi Shabnam, Seed Mike, Mital Seema, Georgieff Michael, Tran Phu
Keywords: Congenital heart disease, Neuropathology, Biomarkers, Biology, developmental, Inflammation and inflammatory markers
12 : 57 PM
BRCC3 Attenuates TIFA-Mediated Noncanonical TGF-β Signaling: Implications in Pulmonary Arterial Hypertension
Wei Tong-you, Yin Qing, Tan Meng, Sun Wei, Shyy John
Final Pr. ID: MP2618
Authors: Wei Tong-you, Yin Qing, Tan Meng, Sun Wei, Shyy John
Keywords: Pulmonary hypertension, Pulmonary vascular biology, Endothelial function, Inflammation, Ubiquitin
11 : 20 AM
Breaking the Barrier: RAGE Deficiency Promotes EndoMT and Male-Predominant Pulmonary Arterial Hypertension
Lawal Odunayo, Niihori Maki, Rafikov Ruslan, Rafikova Olga
Final Pr. ID: MP2609
Authors: Lawal Odunayo, Niihori Maki, Rafikov Ruslan, Rafikova Olga
Keywords: Pulmonary hypertension, Pulmonary vascular biology, Pulmonary artery, Fibrosis, Endothelial