Abstract Body: Background: In Los Angeles County, the impact of high social vulnerability on stroke patient outcomes is a critical area of concern, given the region's diverse socioeconomic landscape and significant health disparities. High social vulnerability among stroke patients can significantly impact their outcomes in several ways, from poorer functional outcomes, access to care, and higher risk for pre-existing conditions, including increased history of behavioral health issues.

Objective: This study aims to explore how high social vulnerability affects stroke outcomes among patients in Los Angeles County Health System, pre-existing co-morbidities, recovery trajectories, and overall health status. And evaluate differences between race, gender and age.

Methods: We conducted a social vulnerability index analysis of stroke patients in the Los Angeles County Health System, utilizing data from medical records, socioeconomic indicators, and healthcare access metrics. Social vulnerability was assessed using indices incorporating factors such as income, education, housing stability, and access to healthcare.

Results: Findings reveal that stroke patients with high social vulnerability experience poorer functional outcomes (p<.05)and increased stroke severity (p<.05), including increased mortality rates, lower functional recovery, and higher rates of complications. Additionally, patients in socioeconomically disadvantaged communities are more likely to face barriers in accessing quality healthcare services, which exacerbates the disparities in stroke outcomes. Latinos faced a twofold increase in poorer outcomes in comparison to other races.

Conclusion: High social vulnerability significantly impacts stroke patient outcomes in Los Angeles County. The findings highlight the need for targeted interventions to improve healthcare access, enhance support services, and address socioeconomic barriers to mitigate the adverse effects on stroke recovery and overall health. Addressing these disparities is essential for reducing health inequities and improving patient outcomes in diverse urban populations.