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American Heart Association

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Final ID: WMP91

Comparison of clinical outcomes and complications in patients undergoing Carotid Artery Stenting (CAS) with or without pre and post-stent balloon angioplasty.

Abstract Body: Background and Objective: Carotid artery stenting (CAS) is a procedure that has been established as a safe and effective alternative to carotid endarterectomy in high surgical risk patients. There are procedural questions that remain unanswered, specifically, the safety of pre-stent balloon angioplasty versus post-stent versus both. The objective of our study is to understand the risk and safety of these procedural techniques.
Methods: Multicenter retrospective data related to angioplasty balloons, stents, complications due to pre and post-stent angioplasty along with the modified Rankin score (mRS) before and after the procedure were collected from January of 2015 until December of 2022. Statistical analysis was performed to correlate this data with risks of complications and clinical outcomes.
Results: A total of 1355 patients were enrolled. We found that patients who underwent pre-stent angioplasty, or both (pre and post-stent angioplasty) had a higher risk of complications compared to those who only had post-stent angioplasty. There were more complications in patients who did not undergo post-stent angioplasty as compared to those who did undergo angioplasty (p=0.018, OR=0.513). Follow-up MRS at 30-90 days was higher if the balloons in both pre-stent angioplasty (p=0.016) and post-stent angioplasty (p=0.020) stent angioplasty were not inflated to nominal pressure. Follow up MRS was statistically higher (p=0.01) in patients with open-cell stents than closed-cell stents. Open-cell stents were more likely to undergo post-stent angioplasty (p<0.001) while closed-cell stents were more likely to undergo pre-stent angioplasty (p=0.002).
Conclusions: Patients who underwent post-stent angioplasty alone had less risks of complications compared to pre-stent angioplasty or combination. This is contrary to prior studies published on this subject and could be related to improvement in technique and in technology in recent years. There is a higher rate of post-stent angioplasty in patient who received open cell stents, but these also had higher mRS at 30-90 days compared to closed cell stents.
  • Martucci, Maria  ( Cleveland Clinic , Cleveland , Ohio , United States )
  • Alaraj, Ali  ( University of Illinois at Chicago , Chicago , Illinois , United States )
  • Niazi, Muhammad  ( WellSpan Health, York, Pennsylvania , York , Pennsylvania , United States )
  • Mansour, Ossama  ( Alexandria University , Alexandria , Egypt )
  • Chen, Michael  ( Rush University Medical Center , Chicago , Illinois , United States )
  • Bushnaq, Saif  ( Texas Tech University , Lubbock , Texas , United States )
  • Tanweer, Omar  ( Baylor St. Lukes Medical Center , Houston , Texas , United States )
  • Ezzeldin, Rime  ( Jordan University of Science and Technology , Irbid , Jordan )
  • Zwein, Mohammad  ( Friendswood High School , Friendswood , Texas , United States )
  • Mealer, Leighann  ( KINGWOOD MEDICAL CENTER , Porter , Texas , United States )
  • Navpreet, Bains  ( University Hospital Missouri, Columbia, Missouri , Columbia , Missouri , United States )
  • Hussain, Shazam  ( CLEVELAND CLINIC , Cleveland , Ohio , United States )
  • Miller, Samantha  ( UTRGV - VALLEY BAPTIST MEDICAL CENT , Harlingen , Texas , United States )
  • Colina, Gabriela  ( Texas Tech University Health Sciences Center , El Paso , Texas , United States )
  • Rodriguez, Gustavo  ( Texas Tech University Health Sciences Center , El Paso , Texas , United States )
  • Maud, Alberto  ( Texas Tech University , El Paso , Texas , United States )
  • Almajali, Mohammad  ( St. Vincent Medical Center , Toledo , Ohio , United States )
  • Barakat, Benan  ( St. Vincent Medical Center , Toledo , Ohio , United States )
  • Edhayan, Gautam  ( University of Texas Medical Branch , Galveston , Texas , United States )
  • Froukh, Musaab  ( Ascension Health , Chicago , Illinois , United States )
  • Salah, Walid  ( University of Utah , Salt Lake City , Utah , United States )
  • Nico, Elsa  ( University of Illinois at Chicago , Chicago , Illinois , United States )
  • Hassan, Ameer  ( UTRGV - VALLEY BAPTIST MEDICAL CENT , Harlingen , Texas , United States )
  • Ashraf, Shehab  ( Alexandria University , Alexandria , Egypt )
  • Radaideh, Yazan  ( Rush University Medical Center , Chicago , Illinois , United States )
  • Quispe-orozco, Darko  ( Texas Tech University , Lubbock , Texas , United States )
  • Zaidat, Osama  ( Mercy Health St Vs Hospital , Toledo , Ohio , United States )
  • Ezzeldin, Mohamad  ( KINGWOOD MEDICAL CENTER , Porter , Texas , United States )
  • Siddiq, Farhan  ( University Hospital Missouri, Columbia, Missouri , Columbia , Missouri , United States )
  • Sheriff, Faheem  ( Texas Tech University Health Sciences Center , El Paso , Texas , United States )
  • Kan, Peter  ( University of Texas Medical Branch , Galveston , Texas , United States )
  • Janjua, Nazli  ( Pomona Valley Hospital Medical Cent , Pomona , California , United States )
  • Asif, Kaiz  ( Ascension Health and UIC - Chicago , Chicago , Illinois , United States )
  • Grandhi, Ramesh  ( University of Utah , Salt Lake City , Utah , United States )
  • Author Disclosures:
    Maria Martucci: DO NOT have relevant financial relationships | Ali Alaraj: DO have relevant financial relationships ; Consultant:Cerenovus:Active (exists now) | Muhammad Niazi: DO NOT have relevant financial relationships | Ossama Mansour: DO NOT have relevant financial relationships | Michael Chen: No Answer | Saif Bushnaq: No Answer | Omar Tanweer: No Answer | Rime Ezzeldin: DO NOT have relevant financial relationships | Mohammad Zwein: No Answer | LeighAnn Mealer: DO NOT have relevant financial relationships | Bains Navpreet: No Answer | Shazam Hussain: DO have relevant financial relationships ; Independent Contractor:Cerenovus:Active (exists now) ; Research Funding (PI or named investigator):Medtronic:Active (exists now) ; Independent Contractor:Rapid Medical :Active (exists now) ; Independent Contractor:Stryker :Active (exists now) ; Consultant:Kaneka:Active (exists now) | samantha miller: No Answer | Gabriela Colina: No Answer | Gustavo Rodriguez: DO NOT have relevant financial relationships | Alberto Maud: No Answer | Mohammad Almajali: No Answer | Benan Barakat: DO NOT have relevant financial relationships | Gautam Edhayan: No Answer | Musaab Froukh: No Answer | Walid Salah: No Answer | Elsa Nico: No Answer | Ameer Hassan: DO have relevant financial relationships ; Consultant:Medtronic, Microvention, Stryker, Penumbra, Cerenovus, Genentech, GE Healthcare, Scientia, Balt, Viz.ai , Insera therapeutics, Proximie, NeuroVasc, NovaSignal, Vesalio, Rapid Medical, Imperative Care, Galaxy Therapeutics, Route 92, Perfuze, CorTech, Shockwave and Xcath:Active (exists now) | Shehab Ashraf: DO NOT have relevant financial relationships | Yazan Radaideh: DO NOT have relevant financial relationships | Darko Quispe-Orozco: No Answer | Osama Zaidat: No Answer | Mohamad Ezzeldin: DO have relevant financial relationships ; Speaker:Viz AI:Active (exists now) ; Other (please indicate in the box next to the company name):Investment in Galaxy Therapeutics:Active (exists now) ; Speaker:Imperative Care:Active (exists now) | Farhan Siddiq: No Answer | Faheem Sheriff: DO NOT have relevant financial relationships | Peter Kan: DO have relevant financial relationships ; Consultant:Stryker:Active (exists now) | Nazli Janjua: DO NOT have relevant financial relationships | Kaiz Asif: DO have relevant financial relationships ; Individual Stocks/Stock Options:Solaris X Labs:Active (exists now) ; Individual Stocks/Stock Options:Galaxy Therapeutics:Active (exists now) ; Individual Stocks/Stock Options:Gravity Medical Technology:Active (exists now) | Ramesh Grandhi: DO have relevant financial relationships ; Consultant:Medtronic Neurovascular:Active (exists now) ; Consultant:Cerenovus:Active (exists now) ; Consultant:Rapid Medical:Active (exists now) ; Consultant:Stryker Neurovascular:Active (exists now) ; Consultant:Balt:Active (exists now)
Meeting Info:
Session Info:

Neuroendovascular Moderated Poster Tour I

Wednesday, 02/05/2025 , 06:00PM - 07:00PM

Moderated Poster Abstract Session

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