Abstract Body (Do not enter title and authors here): Background
Cardiovascular disease (CVD) risk factors are highly prevalent and rising among women of reproductive age. Mothers of young children (ages 0–5) face unique barriers to cardiovascular health, including lower physical activity, suboptimal diet, and heightened psychosocial stress. However, few studies or interventions have specifically focused on this population.

Objective
To explore health-related priorities, social needs, and preferences for CVD prevention strategies among socially vulnerable mothers of young children, to inform the design of a context-specific CVD prevention intervention.

Methods
We conducted a pilot mixed-methods study, comprising of semi-structured 1:1 phone interview with mothers aged 18–49, who were primary caregivers of children aged 0–5 from under-resourced New York City neighborhoods between July - November 2024. Participants also completed questionnaires on sociodemographic information, clinical history, including pregnancy-related complications, health related social needs, health behaviors and psychosocial factors.

Results
Participants (N=22) had a median age of 36 [interquartile range; IQR 34–39] years, and 11 (50.0%) were Mandarin-speaking, 8 (36.4%) were Spanish-speaking. A majority (77.3%) reported their income did not adequately meet household needs and 13 (59.1%) had ≤ high school education. Median Perceived Stress Scale -10 score was 21 [20–24], Global Perceived Stress Score was 7 [4–9.5], Patient Health Questionnaire-8 score (depressive symptoms) was 7 [3–10]. Over half (59.1%) perceived their CVD risk as below average, despite having multiple risk factors.
Thematic analysis identified mothers’ top health priorities as improving diet, increasing physical activity, and managing stress—often motivated by a desire to “get back” to their identity or stay healthy for their children. Barriers included lack of time, energy, and support. Facilitators included access to walking, meal/activity planning, and a sense of accomplishment. Participants expressed strong preference for peer-supported, practical, stress-relieving interventions and in-person sessions to connect with other mothers.

Conclusion
Socially vulnerable mothers of young children experience high psychosocial stress and internal conflict around self-prioritization. Findings underscore the need for interventions that address social resource barriers, offer peer support, include in-person components, and provide practical tools for stress and lifestyle management.