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American Heart Association

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Final ID: MP137

AI-Enhanced Automated Vascular Risk Assessment Using Multi-Territory Non-Coronary Imaging: A Systematic Review

Abstract Body (Do not enter title and authors here): Introduction
Standard cardiovascular testing relies primarily on medical history and coronary imaging, which may fail to detect the full extent of systemic vascular disease. Using AI in non-coronary vascular blood vessel areas, such as the carotid, aortic, and peripheral systems, may offer a thorough investigation and provide a better understanding of one's risk. Currently, manual assessments require a significant amount of time, and the varying interpretations of different experts often influence their accuracy.
Hypothesis
Applying AI to the automated analysis of imaging for vascular diseases across multiple territories yields more accurate predictions of major adverse cardiovascular events than traditional risk scores and image analysis from a single area.
Methods
Using PRISMA standards, we searched a range of databases (from 2018 to 2024) for studies focused on AI algorithms in non-coronary vascular imaging. Two researchers evaluated the studies and pulled out the information on predicting cardiovascular death, heart attack and stroke. Secondary outcomes included measuring the frequency with which each test produces the same result, assessing the time required for processing, and evaluating how well they correlate with established vascular biomarkers. A review of study quality was conducted using the QUADAS-2 and NOS.
Results
All 23 selected studies (n = 28,894) found that AI-enhanced analysis of vascular parameters consistently predicted risk more accurately than traditional risk scales. Measurements of carotid thickness and stiffness of the aorta and arteries of the legs were highly reproducible and required much less analysis time using automation. Authors across various studies found that models using data from multiple areas performed better than models trained solely on one area.
Conclusion
This analysis demonstrates that AI features in the automated analysis of imaging from multiple locations outside the heart enhance both the accuracy and efficiency of cardiovascular risk estimation. It enables thorough surveying of the vascular system for precision cardiology.
  • Jabeen, Shafaq  ( Karachi Medical and Dental College , Karachi , Sindh , Pakistan )
  • Jawed, Inshal  ( Dow Medical College , Karachi , Pakistan )
  • Tilokani, Hersh  ( UCLA , Los Angeles , California , United States )
  • Ali Farhan Abbas Rizvi, Syed  ( Jinnah Sindh Medical University , Karachi , Pakistan )
  • Abdul Qadir, Muhammad Umair  ( Dow Medical College , Karachi , Pakistan )
  • Mekowulu, Favour  ( Specialist Practice for Cardiology & Pulmonology Eggenfelden , Eggenfelden , Germany )
  • Alam, Mohammad Omer  ( Jinnah Sindh Medical University , Karachi , Pakistan )
  • Bin Gulzar, Abu Huraira  ( Services Institute Medical Sciences , Lahore , Pakistan )
  • Khalid, Aizaz Anwar  ( Peshawar Medical College , Swabi , Pakistan )
  • Author Disclosures:
    Shafaq Jabeen: DO NOT have relevant financial relationships | Inshal Jawed: DO NOT have relevant financial relationships | Hersh Tilokani: DO NOT have relevant financial relationships | Syed Ali Farhan Abbas Rizvi: No Answer | muhammad umair abdul qadir: No Answer | Favour Mekowulu: DO NOT have relevant financial relationships | Mohammad Omer Alam: DO NOT have relevant financial relationships | Abu Huraira Bin Gulzar: DO NOT have relevant financial relationships | Aizaz Anwar Khalid: DO NOT have relevant financial relationships
Meeting Info:

Scientific Sessions 2025

2025

New Orleans, Louisiana

Session Info:

Transforming Cardiac Imaging and Risk Assessment Through AI

Saturday, 11/08/2025 , 12:15PM - 01:25PM

Moderated Digital Poster Session

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