Turning the Corner: The Life Saving Potential of Timely CABG Intervention in Elderly Ventilated Patients: A Case Series AHA Conference Repository

American Heart Association

Final ID: MP75

Turning the Corner: The Life Saving Potential of Timely CABG Intervention in Elderly Ventilated Patients: A Case Series

Abstract Body (Do not enter title and authors here):

Introduction:
As the global elderly population grows, so does the incidence of acute coronary syndrome (ACS) requiring urgent intervention. Emergency coronary artery bypass grafting (CABG) may offer a survival benefit, but concerns remain about its feasibility and safety in critically ill elderly patients with multiple comorbidities.
Description of Case:
This single-surgeon case series includes eight patients >65 years old who underwent emergency CABG for ACS between September 2023 and September 2024. Comorbidities included diabetes, hypertension, CKD, COPD, and previous stroke. All patients were critically ill, requiring combinations of inotropes, intra-aortic balloon pump (IABP), and mechanical ventilation. Ejection fractions ranged from 20–45%, and EuroSCOREs ranged from 10.86 to 30.45. Standard cardiopulmonary bypass with moderate hypothermia and a single aortic cross-clamp was used. Postoperatively, complications included transient ischemic attacks, dialysis-requiring renal dysfunction, atrial fibrillation, and infections. All patients survived; extubation times ranged from 7 to 70 hours, and hospital stays from 5 to 12 days.
Discussion:
This case series examines outcomes of CABG in elderly patients, emphasizing that despite multiple comorbidities, through physiological assessment, CABG can safely be performed in critically ill patients Although the LVEF was low and multiple comorbidities like diabetes and chronic kidney disease, signify the importance of a comprehensive assessment of physiology beyond standard biomarkers is necessary to determine readiness for surgery. Ventilation times variations highlighted the consequences of pulmonary and hematological challenges encountered in these patients. Recent advances in surgical techniques and perioperative care have improved outcomes, and most patients showed enhanced quality of life and physical function within a year post-surgery.

Conclusion:
Emergency CABG can be a lifesaving therapy in critically ill elderly ACS patients. With careful perioperative management, advanced age and comorbidity burden should not preclude surgical intervention

Khan, Muhammad Qaiser Aziz ( Liaquat National Hospital and Medical College , Karachi , Pakistan )
Sarhandi, Maryam Nasteen ( Liaquat National Hospital and Medical College , Karachi , Pakistan )
Khurram, Muqaddas Binte ( Liaquat National Hospital and Medical College , Karachi , Pakistan )
Zaheer, Amna ( Liaquat National Medical College , Karachi , Pakistan )
Sarhandi, Zainab ( Liaquat National Hospital and Medical College , Karachi , Pakistan )
Zaman, Asad ( CMH Multan Institute , Multan , Pakistan )
Panjwani, Shaliza ( Dow University of Health Sciences , Karachi , Pakistan )
Bukhari, Syed Mohsin Raza ( Nishtar Medical University , Multan , Pakistan )
Humayun, Mohammad Abdullah ( Mayo Clinic , Scottsdale , Arizona , United States )
Shrestha, Jamuna ( Manipal College of Medical Sciences , Pokhara , Nepal )

Author Disclosures:

Muhammad Qaiser Aziz Khan: