Efficacy of OCT versus angiography in post-procedural lesions complications after percutaneous coronary intervention with drug-stent implementations: A systematic review and meta-analysis
Abstract Body (Do not enter title and authors here): Background: Although recent studies have suggested the advantages of utilizing optical coherence tomography (OCT) for image guidance during percutaneous coronary intervention (PCI) with drug-eluting stent implantation over conventional angiography, the specific impact on post-procedural lesion complications has remained uncertain. To address this gap, we conducted an updated systematic review and meta-analysis focusing on post-procedural lesion complications associated with OCT-guided versus angiography-guided procedures in lesions undergoing PCI with drug-eluting stent implementation. Methods: We searched systematically through Pubmed, Embase, and Cochrane for randomized controlled trials(RCTs), which included lesions undergoing PCI and drug-stent deployment guided by OCTversus angiography. Our primary outcome of interest was (1) stent malposition under OCT analysis. We also included the following secondary outcome: (2) dissections under OCT analysis. We excluded studies that did not use OCT imaging to analyze post-procedure lesions. Risk Ratios(RRs) with 95% confidence interval (CI) were pooled across studies using a random effect model. Results: Five RCTs comprising 3,266 lesions undergoing OCT or Angio PCI-guided and drug stent implementation were included, of whom 1,549(48,34%) underwent OCT. The number of moderate-severe calcified lesions was 370 (11.33%). Our results show a significant association with decreased stent malposition risk in the OCT group, showed a significant decrease in post-procedure risk regarding stent malpositioning ( RR: 0.80; 95% CI: 0.75-0.84; P<0.001; Fig.1) compared to angiography. However, our findings did not detect any difference in dissection undergoing OCT post-procedure analysis (RR: 1.58; 95% CI: 0.31- 8.06; P=0.583; Fig.2)., compared to the angiography group. Conclusion: In this meta-analysis comparing OCT versus angiography in lesion complications post-procedure undergoing PCI and drug-stent implementation, the OCT group was associated with decreased stent malposition.
Katsuyama, Eric
( Faculty of Medicine of ABC
, Sao Paulo
, Brazil
)
Gioli-pereira, Luciana
( Albert Einstein Israelite Hospital
, Sao Paulo
, Brazil
)
Fukunaga, Christian
( Faculty of Medicine of ABC
, Sao Paulo
, Brazil
)
Andrade, Naieli
( Escola Bahiana de Medicina e Saúde Pública
, Salvador
, Brazil
)
Petri Santos Pinheiro, Rafael
( Universidade Federal do Rio de Janeiro
, Rio de Janeiro
, Brazil
)
Prata, Alonzo
( UFES
, Vitoria
, Brazil
)
Scardini, Pedro Gabriel
( EMESCAM
, Vitoria
, Brazil
)
Coan, Ana Carolina
( Federal University of Espirito Santo
, Vitoria
, Brazil
)
Falco Neto, Wilson
( Faculdade de Medicina de Catanduva
, Catanduva
, Brazil
)
Fernandes, Julia
( Faculdade Israelita de Ciências da Saúde Albert Einstein
, Santos
, Brazil
)
Author Disclosures:
Eric Katsuyama:DO NOT have relevant financial relationships
| Luciana Gioli-Pereira:DO NOT have relevant financial relationships
| Christian Fukunaga:DO NOT have relevant financial relationships
| Naieli Andrade:No Answer
| Rafael Petri Santos Pinheiro:DO NOT have relevant financial relationships
| Alonzo Prata:DO NOT have relevant financial relationships
| Pedro Gabriel Scardini:DO NOT have relevant financial relationships
| Ana Carolina Coan:DO NOT have relevant financial relationships
| Wilson Falco Neto:DO NOT have relevant financial relationships
| Julia Fernandes:DO NOT have relevant financial relationships