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American Heart Association

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Final ID: 4137781

Relationship between Race, Predelivery Cardiology Care and Cardiovascular Outcomes in Pre-eclampsia/Eclampsia among a Commercially Insured Population

Abstract Body (Do not enter title and authors here): BACKGROUND: Inequities in Preeclampsia/Eclampsia (PrE/E) persist. It is unknown if the receipt of cardiology care relates to future risk of major adverse cardiovascular events (MACE) in Black and White patients with PrE/E. We sought to determine the cumulative incidence of MACE by race and whether predelivery cardiology care was associated with the hazard of MACE up to 1-year post-delivery for Black and White patients with PrE/E.
METHODS: Using Optum’s Clinformatics® Data Mart Database (CDM), we identified Black and White patients with PrE/E who had a delivery between 2008 to 2019. MACE was defined as the composite of heart failure, acute myocardial infarction, stroke, and death. Cumulative incidence functions were used to compare the incidence of MACE by race. Cox regression models were used to assess the hazard of MACE by cardiology care for Black and White patients.
RESULTS: Among 29,336 patients (83.4% White, 16.6% Black, mean age of 30.9 years) with PrE/E, 11.2% received cardiology care (10.9% White, 13.0% Black). Black patients had a higher incidence of MACE than White patients at 1-yr post-delivery (2.7% vs 1.4%). After adjusting for age and clinical comorbidities, receipt of cardiology care was associated with lower hazard of MACE for White patients (HR= 0.68, 95%CI: 0.50-0.92 p=0.013) but not Black patients (HR: 1.22, 95% CI: 0.82-1.81; p= 0.328). The interaction effect between race and cardiology care was statistically significant (p=0.013)
CONCLUSIONS: Among a well-insured population of patients with PrE/E, Black patients had a higher cumulative incidence of MACE up to a year post-delivery. However, cardiology care significantly lowered the hazard of MACE for only White women. This observation does not suggest that cardiology care is detrimental to Black individuals but underscores the necessity to investigate why outcomes are disparate among these racial groups.
  • Bolakale-rufai, Ikeoluwapo  ( Indiana University , Indianapolis , Indiana , United States )
  • Breathett, Khadijah  ( Indiana University , Indianapolis , Indiana , United States )
  • Knapp, Shannon  ( Indiana University SOM , Indianapolis , Indiana , United States )
  • Khan, Sadiya  ( Northwestern University , Oak Park , Illinois , United States )
  • Tucker Edmonds, Brownsyne  ( Indiana University SOM , Indianapolis , Indiana , United States )
  • Brewer, Laprincess  ( MAYO CLINIC , Rochester , Minnesota , United States )
  • Mohammed, Selma  ( Creighton University , Omaha , Nebraska , United States )
  • Johnson, Amber  ( University of Chicago , Chicago , Illinois , United States )
  • Mazimba, Sula  ( UNIVERSITY VIRGINIA , Charlottesville , Virginia , United States )
  • Addison, Daniel  ( Ohio State University , Columbus , Ohio , United States )
  • Author Disclosures:
    Ikeoluwapo Bolakale-Rufai: DO NOT have relevant financial relationships | Khadijah Breathett: DO NOT have relevant financial relationships | Shannon Knapp: DO NOT have relevant financial relationships | Sadiya Khan: DO NOT have relevant financial relationships | Brownsyne Tucker Edmonds: DO NOT have relevant financial relationships | LaPrincess Brewer: DO NOT have relevant financial relationships | Selma Mohammed: DO have relevant financial relationships ; Other (please indicate in the box next to the company name):Medtronic:Active (exists now) ; Other (please indicate in the box next to the company name):AstraZeneca:Active (exists now) | Amber Johnson: DO NOT have relevant financial relationships | Sula Mazimba: DO NOT have relevant financial relationships | Daniel Addison: DO NOT have relevant financial relationships
Meeting Info:

Scientific Sessions 2024

2024

Chicago, Illinois

Session Info:

QCOR Early Career Investigator Abstract Award Competition

Friday, 11/15/2024 , 11:00AM - 12:15PM

Abstract Oral Session

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