Abstract Body: Introduction: Prolonged venous outflow (PVT+) is a surrogate marker for venous outflow. The PVT is defined as the presence or absence of time-to-maximum >= 10 seconds timing in either the superior saggital sinus or torcula on visual time-to-maximum maps from perfusion imaging. This novel metric has been shown to be associated with higher odds of mortality and lower liklihood of functional recovery, despite successful reperfusion with mechanical thrombectomy. The study aims to assess the relationship between PVT and length of hospitalization. We hypotheisze that PVT+ will be associated with longer lengths of stay.
Methods: Acute large vessel occlusion ischemic stroke patients successfully reperfused with thrombectomy between 01/2017-09/2022 were retrospectively reviewed. Primary outcome was length of hospitalization. Multivariable linear regressions were performed for the outcome of length of stay.
Results: Of 109 patients, the median age was 71 (IQR 62-80) years. PVT+ patients had significantly longer lengths of stay than PVT- patients (9 days (IQR 6-18) versus 6 days (IQR 4-12), p=0.03). In multivariable regressions adjusting for other clinical covariables, PVT+ was significantly associated with two additional days of hospitalization compared to PVT- patients (p=0.03).
Conclusion: Despite successful reperfusion, PVT+ was associated with two additional days of hospitalization on average comapred to PVT- patients. PVT is a simple, qualitative metric that demonstrates robustness in correlations with a range of short and long term clinical outcomes, and thus this novel surrogate of venous outflow may be informative for clinical practice.