Abstract Body: Background While overall death rates of stroke have decreased, minority populations continue to experience an increase in stroke related death. There are known sociodemographic variations in stroke awareness. The lowest reported knowledge of stroke signs is within the Hispanic (58%) communities, trailing behind the Black (64%) and white (71%) communities. Understanding the relationship between social determinants of health (SDoH) and stroke awareness may help bridge the gap between minority populations and stroke care. Purpose The purpose of this study is to determine if relationships exist between SDoH and stroke awareness and severity in Brooklyn, New York. Methods An exploratory descriptive retrospective secondary analysis was completed; examining data from patients discharged from a hospital in Brooklyn, New York. 1162 patients discharged with a diagnosis of stroke from January 2021 to July 2023 were included. Data was gathered from the Get With The Guidelines. Data included: demographics, arrival method, initial NIHSS score, symptom discovery time, arrival time, and discharge NIHSS score. Data was analyzed to determine if relationships exist between SDoH and stroke awareness. Results There is a significant difference in timeliness to seek care based on race and ethnicity. After controlling for age, gender, zip code, and insurance type, Hispanic patients take three times as long to seek care, while Black patients take twice as long, and Asian patients take one time as long, compared to their white non-Hispanic counterparts. Payer status and race influence severity as evidenced by a significant difference in NIHSS, with Asian and public insurance patients having a higher NIHSS on arrival when compared to white non-Hispanic patients and those with private insurance. Lastly, a patient’s choice of transportation may be influenced by age and payer status, with those under 65 and/or with private insurance less likely to call an ambulance. Conclusions: This study highlights the importance of providing culturally and linguistically tailored education to populations in need. Using the findings of this study, the stroke program coordinator can provide targeted education rather than generalized education. This study supports the need for community-informed care for stroke patients, focused on increasing stroke awareness in minority populations. This study may act as a blueprint for stroke programs by providing a guide for planning community-centered education.