Abstract Body: Objectives
Hypertensive Emergency is an acute, marked elevation in blood pressure that is associated with signs of target-organ damage. We sought to determine the outcome of hypertensive emergency in patients with dementia.

Methods
Using the 2020 National Inpatient Sample Database (NIS), we conducted a retrospective analysis of patients admitted for Hypertensive Emergency as a principal diagnosis according to ICD-10 codes. Our primary outcome was inpatient mortality. Secondary outcomes include acute kidney injury (AKI), cerebrovascular accident (CVA), myocardial infarction (MI), acute hypoxic respiratory failure, length of hospital stays, and hospital charges between groups. (Patient with or without Dementia)

Results
A total of 59690 patients were admitted for hypertensive emergency. Of those, 4.3% had a history of dementia. Patients with a history of dementia were older (80 years, 95% CI 79 – 81 VS 59 years, 95% CI 58 – 59). There was no statistically significant difference in inpatient mortality (p=0.1363), acute kidney injury (p=0.7461), cerebrovascular accident (p=0.7712), myocardial infarction (p=0.1517), and acute hypoxic respiratory failure (p=0.3088). Patients with dementia had increased length of hospital stays (6 days, 95% CI 5 – 6 VS 4 days, 95% CI 3 – 4) and total hospital charges ($55,302.18, 95 % CI $49,669.87 - $60,934.5 VS $46,685.84, 95% CI $45,231.38 - $48,140.3)

Conclusion
This study shows that there is no difference in in-hospital mortality when comparing patients with dementia and the general population admitted for a hypertensive emergency. Patients with dementia had increased length of hospital stays and charges.