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American Heart Association

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Final ID: Mo2019

High Sensitivity and Specificity of Electrocardiogram-Based AI Models for Diagnosing Peripartum Cardiomyopathy: A Systematic Review and Meta-Analys

Abstract Body (Do not enter title and authors here): INTRODUCTION
Artificial intelligence electrocardiograms are considered efficient for estimating ejection fraction in heart failure patients. However, whether this method is a potential tool to diagnose peripartum cardiomyopathy has not been thoroughly explored.
RESEARCH QUESTIONS
Are electrocardiogram-Base AI models able to predict peripartum cardiomyopathy?
AIMS
We conducted a meta-analysis and systematic review to evaluate the accuracy of electrocardiogram-base artificial intelligence models to predict peripartum cardiomyopathy.
METHODS
We searched PubMed, Embase and Cochrane. We computed true positives, true negatives, false positives and false negatives events to estimate pooled sensitivity, specificity and area under the curve under random mode. We used R 4.3.1 to perform statistics.
RESULTS
We identified 3 studies of data from 4 different datasets, including 425 patients evaluated for peripartum cardiomyopathy. The mean age ranged from 29 to 33 years. Multiparity ranged from 20.58% to 36.94%. Black population ranged from 58.13% to 62.6% Chronic hypertension ranged from 1.56% to 9.5%. Gestational hypertension ranged from 28% to 32.8% .The AI enabled electrocardiogram data yielded areas under the receiver operator of 0.900, sensitivity of 0.841(0.749-0.903), and specificity of 0.840(0.714-0.917) to predict for peripartum cardiomyopathy.
CONCLUSIONS
In this systematic review and meta-analysis, the use of electrocardiogram-based artificial intelligence models demonstrated high sensitivity and specificity for the diagnosis of peripartum cardiomyopathy.
  • Aquino Pereira Lima, Christopher  ( Universidade nove de julho , São Paulo , Brazil )
  • Jorgetti, Joao  ( Sao Caetano University , Sao paulo , Brazil )
  • Dos Santos Borges, Rafael  ( Federal University of Minas Gerais , Belo Horizonte , Brazil )
  • Carvalho Ferreira, Andre  ( Roger Williams Medical Center , Providence , Rhode Island , United States )
  • Fragnan, Murilo  ( Universidade nove de julho , São Paulo , Brazil )
  • Suruagy-motta, Ricardo  ( Cesmac University Center , Maceio , Brazil )
  • Neves, Gabriel  ( State University of Para , Belem , Brazil )
  • Galvao De Oliveira Oldra, Leonardo  ( Anhembi Morumbi University , Sao Paulo , Brazil )
  • Farias, Carlos  ( Universidade nove de julho , São Paulo , Brazil )
  • Da Silva, Leonardo D  ( FMUSP , Sao Paulo , Brazil )
  • De Sousa, Pedro Antônio  ( Federal University of Uberlândia , Uberlândia , Brazil )
  • Nascimento, Eriky  ( university ninith of july , Sao paulo , Brazil )
  • Author Disclosures:
    Christopher Aquino Pereira Lima: DO NOT have relevant financial relationships | joao jorgetti: DO NOT have relevant financial relationships | Rafael Dos Santos Borges: DO NOT have relevant financial relationships | Andre Carvalho Ferreira: No Answer | Murilo Fragnan: DO NOT have relevant financial relationships | Ricardo Suruagy-Motta: DO NOT have relevant financial relationships | Gabriel Neves: DO NOT have relevant financial relationships | Leonardo Galvao de Oliveira Oldra: DO NOT have relevant financial relationships | Carlos Farias: DO NOT have relevant financial relationships | LEONARDO D DA SILVA: DO NOT have relevant financial relationships | Pedro Antônio De Sousa: No Answer | Eriky Nascimento: No Answer
Meeting Info:

Scientific Sessions 2025

2025

New Orleans, Louisiana

Session Info:

AI Under the Hood: Performance, Precision, and Model Accuracy

Monday, 11/10/2025 , 01:00PM - 02:00PM

Abstract Poster Board Session

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