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American Heart Association

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Final ID: MP685

Single Chamber (Right Atrial) Leadless Pacemaker to Prevent Ventricular Tachycardia

Abstract Body (Do not enter title and authors here): Introduction
Sudden changes in ventricular cycle lengths (or short-long-short [S-L-S] sequences) can initiate polymorphic ventricular tachycardia (VT). This pattern involves a premature ventricular beat (PVC), followed by a compensatory pause and subsequent premature beat. The compensatory pause leading to the long cycle is followed by a prolonged repolarization phase. Suppressing S-L-S sequences with anti-bradycardic pacing may prevent polymorphic VT in at-risk patients. Herein we describe a case of a patient being treated for fungal endocarditis who developed recurrent VT storm in whom anti-bradycardia pacing via a single-chamber right atrial pacemaker prevented further sustained VT episodes.

Case
A 69-year-old patient with fungal bioprosthetic aortic valve endocarditis developed sustained VT, for which he was successfully resuscitated. He was prescribed a secondary prevention wearable defibrillator lifevest on discharge, but over a 2-week period the patient received 6 appropriate shocks by his wearable defibrillator for polymorphic and monomorphic VT episodes despite treatment with multiple anti-arrhythmic agents. In-patient telemetry identified S-L-S sequence preceding the VT episodes. Subsequently, a single chamber right atrial leadless pacemaker was placed and programmed to pace at eighty beats per minute. At 8 weeks post-implant, he experienced no further VT episodes (non-sustained or sustained).

Discussion
Due to ongoing treatment for fungemia, placement of a transvenous pacing/defibrillator system was a relative contraindication, due to high risk for cardiac device infection. While a subcutaneous ICD could have been implanted with less infectious risk, it does not have pacing function, and would not have prevented further VT episodes.

Conclusion
This case highlights a unique management strategy utilizing anti-bradycardia pacing via a single chamber right atrial leadless pacemaker to prevent ventricular arrhythmias triggered by S-L-S sequences when other treatment options were less plausible.
  • Weng, John  ( Mount Sinai Hospital , New York , New York , United States )
  • Naraparaju, Ankita  ( Mount Sinai Hospital , New York , New York , United States )
  • Galvani, Eileen  ( Mount Sinai Hospital , New York , New York , United States )
  • Miller, Marc  ( Mount Sinai Hospital , New York , New York , United States )
  • Author Disclosures:
    John Weng: DO NOT have relevant financial relationships | Ankita Naraparaju: No Answer | Eileen Galvani: DO NOT have relevant financial relationships | Marc Miller: No Answer
Meeting Info:

Scientific Sessions 2025

2025

New Orleans, Louisiana

Session Info:

Novel Innovations and Techniques for Leadless Pacing

Saturday, 11/08/2025 , 01:45PM - 02:55PM

Moderated Digital Poster Session

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