Logo

American Heart Association

  15
  0


Final ID: Sa1038

Chronic kidney disease testing in patients with hypertension

Abstract Body (Do not enter title and authors here):
Introduction:
All hypertensive patients should have chronic kidney disease (CKD) testing with estimated glomerular filtration rate (eGFR) and urine albumin to creatinine ratio (ACR) according to KDIGO guidelines. However, rates of testing for CKD, especially with ACR remain low.

Research Question:
What is the prevalence of testing for CKD in older adult patients with hypertension in two large health systems.

Methods:
We present data from patients from two health systems which participated in an NIH-funded, pragmatic, hybrid implementation effectiveness study assessing a virtual collaborative care clinic (vCCC) in large health systems. Patients ≥65 years of age with a systolic blood pressure of >160 mm Hg or two consecutive systolic blood pressure readings of >140 mm Hg were included. Testing for CKD and other baseline characteristics were obtained through the PCORnet common data model. Measures of CKD testing included eGFR, ACR, and urine protein to creatinine ratio (PCR) in the 2 years prior to enrollment. Categorial variables were reported as frequencies and percentage and continuous variables were reported as mean and standard deviation.

Results:
A total of 1000 patients were enrolled in the study, with mean age of 73.3 ± 5.6 years, 51.3% females, 87.7% white. Of the 1000 patients, only 3.2% had no CKD testing; but 75.8% of patients only had eGFR testing and only 20.9% of patients had both eGFR and urinary testing with ACR or PCR. One patient had only ACR without eGFR. Those with both diabetes and hypertension (28.8% of the enrolled participants), had higher proportion of patients (53.1%) with CKD testing with both eGFR and ACR or PCR. Black race, and Hispanic ethnicity also had a higher proportion of CKD testing with both eGFR and ACR or PCR compared to the whole group. Table 1 describes detailed demographics and baseline characteristics associated with CKD testing.

Conclusions:
The prevalence of CKD testing in older patients with hypertension – who have a higher risk of CKD, remains low in the real world despite published guidelines. CKD testing is better in certain groups such as those with both hypertension and diabetes. These data demonstrate a large gap in guidelines and clinical practice and identify areas of opportunities for early detection of CKD.
  • Ramakrishnan, Madhuri  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Burns, Jeffrey  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Gupta, Aditi  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Supiano, Mark  ( University of Utah , Salt Lake City , Utah , United States )
  • Adomako, Emmanuel  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Song, Xing  ( University of Missouri - Columbia , Columbia , Missouri , United States )
  • Young, Kate  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Pradeep Kumar, Danya  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Mahnken, Jonathan  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Chandaka, Sravani  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Abu-el-rub, Noor  ( University of Kansas Medical Center , Kansas City , Kansas , United States )
  • Author Disclosures:
    MADHURI RAMAKRISHNAN: DO NOT have relevant financial relationships | Jeffrey Burns: DO have relevant financial relationships ; Research Funding (PI or named investigator):Alzheimer's Association:Active (exists now) ; Other (please indicate in the box next to the company name):IntraCellular Therapies; Data Monitoring Committee:Active (exists now) ; Consultant:Roche:Active (exists now) ; Consultant:New Amsterdam Pharma:Active (exists now) ; Consultant:Labcorp:Past (completed) ; Consultant:Eisai:Active (exists now) ; Consultant:Renew Biotechnologies:Active (exists now) ; Speaker:Eli Lilly:Active (exists now) ; Consultant:Eli Lilly:Active (exists now) ; Research Funding (PI or named investigator):Roche:Past (completed) ; Research Funding (PI or named investigator):Ionis:Active (exists now) ; Research Funding (PI or named investigator):Astra-Zeneca:Past (completed) ; Research Funding (PI or named investigator):Biogen:Past (completed) ; Research Funding (PI or named investigator):Eli Lilly:Active (exists now) | Aditi Gupta: DO NOT have relevant financial relationships | Mark Supiano: No Answer | Emmanuel Adomako: DO NOT have relevant financial relationships | Xing Song: DO NOT have relevant financial relationships | Kate Young: DO NOT have relevant financial relationships | Danya Pradeep Kumar: DO NOT have relevant financial relationships | Jonathan Mahnken: No Answer | Sravani Chandaka: No Answer | Noor Abu-el-rub: No Answer
Meeting Info:

Scientific Sessions 2025

2025

New Orleans, Louisiana

Session Info:

Extending the Reach: Epidemiology and Therapeutic Innovation in Cardiovascular Care for Late-Stage CKD

Saturday, 11/08/2025 , 02:30PM - 03:30PM

Abstract Poster Board Session

More abstracts on this topic:
A cerebrovascular longitudinal atlas: different rates of morphological change in aneurysm patients associated with hypertension and diabetes

Chien Aichi, Salamon Noriko, Vinuela Fernando, Szeder Viktor, Colby Geoffrey, Jahan Reza, Boyle Noel, Villablanca Juan, Duckwiler Gary

A pharmacist-led, population health approach to optimizing care in patients with hypertension and type II diabetes mellitus in minority groups

Doyle Julie, Haftel Elizabeth, Monroe Janet, Chen Zsu-zsu, Benson Mark, Yankama Tuyen, Adam Atif, Rubin Rochelle

More abstracts from these authors:
Enrollment strategies that yield a representative and generalizable trial population for hypertension research.

Adomako Emmanuel, Conroy Margaret, Burns Jeffrey, Gupta Aditi, Supiano Mark, Ramakrishnan Madhuri, Song Xing, Young Kate, Pradeep Kumar Danya, Mahnken Jonathan, Chandaka Sravani, Abu-el-rub Noor

Blood Pressure Variability and Implications for Trial Screening

Song Xing, Burns Jeffrey, Gupta Aditi, Supiano Mark, Conroy Molly, Chandaka Sravani, Abu-el-rub Noor, Young Kate, Mahnken Jonathan, Barlocker Jackson, King Jordan

You have to be authorized to contact abstract author. Please, Login
Not Available