Abstract Body (Do not enter title and authors here): Background: Catheter ablation is a common procedure carried out in patients with repaired congenital heart defects due to indications such as atrial and ventricular arrhythmias. We examined the impact of repaired congenital heart defects on in-patient outcomes among hospitalized patients following catheter ablation procedures.

Objective: To examine the impact of repaired congenital heart defects on in-patient outcomes among hospitalized patients following catheter ablation procedures.

Methods: The National Inpatient Sample (NIS) data collected from 2016 – 2020 was used to conduct a retrospective cohort analysis. Multivariate logistic and linear regression models were employed to examine the association between corrected congenital heart defects and inpatient all-cause mortality, length of stay, and total hospital charges among hospitalized patients following catheter ablation procedures.

Results: In the adjusted analyses, patients who had catheter ablation procedures with an associated history of repaired congenital heart defect had 1.4 times (AOR: 1.40; 95% Cl: 1.10-1.90) higher odds of inpatient all-cause mortality relative to those without a corrected congenital
heart defect. Also, they were 1.6 times (AOR: 1.60; 95% Cl: 1.10-2.30) more likely to have longer length of stay of more than 5 days compared to five days or less. Additionally, patients with catheter ablation procedures with associated repaired congenital heart defects
had $15,680 (95% Cl: $5,560.3-$20,540.4) higher hospital costs compared to their counterparts with non-repaired congenital heart defects.

Conclusion:
Odds of Mortality, length of hospital stay, and hospital charges were higher in patients with repaired congenital heart defects following catheter ablation procedures. Further studies will be needed to evaluate predictors of mortality as this will assist Electrophysiologists in being better equipped and prepared to manage these patients when the need for catheter ablation procedures arises