Scientific Sessions 2025  /  Transformative Advances in Genome Engineering for Precision Therapy  /  Developing single course in vivo gene editing therapies for hyperlipidemia
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American Heart Association

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Developing single course in vivo gene editing therapies for hyperlipidemia

  • Kathiresan, Sekar  ( Verve Therapeutics , Boston , Massachusetts , United States )
  • Musunuru, Kiran  ( University of Pennsylvania , Philadelphia , Pennsylvania , United States )
  • Ishikawa, Kiyotake  ( ICAHN SCHOOL OF MEDICINE MOUNT SINA , New York , New York , United States )
    • Author Disclosures:
    Sekar Kathiresan: DO have relevant financial relationships ; Executive Role:Verve Therapeutics:Active (exists now) | Kiran Musunuru: DO have relevant financial relationships ; Individual Stocks/Stock Options:Verve Therapeutics:Active (exists now) ; Research Funding (PI or named investigator):Beam Therapeutics:Active (exists now) ; Research Funding (PI or named investigator):Nava Therapeutics:Active (exists now) ; Advisor:Capstan Therapeutics:Active (exists now) ; Advisor:LEXEO Therapeutics:Active (exists now) ; Ownership Interest:Variant Bio:Active (exists now) ; Advisor:Verve Therapeutics:Active (exists now) | Kiyotake Ishikawa: DO NOT have relevant financial relationships
Meeting Info:

Scientific Sessions 2025

2025

New Orleans, Louisiana

Session Info:

Transformative Advances in Genome Engineering for Precision Therapy

Saturday, 11/08/2025 , 09:45AM - 11:00AM

Cardiovascular Seminar

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RNA editing: a tractable future therapeutic?

Weldy Chad, Gan Li-ming, Stafforst Thorsten

Development and evolution of novel genome engineering technologies

Newby Gregory, Gaudelli Nicole, Liu David

More abstracts from these authors:
Design of Heart-2: a phase 1b clinical trial of VERVE-102, an in vivo base editing medicine delivered by a GalNAc-LNP and targeting PCSK9 to durably lower LDL cholesterol

Vafai Scott, Fiedorek Fred, Karsten Verena, Jensen Chelsey, Falzone Richard, Lister Troy, Stolz Leslie, Khera Amit, Kathiresan Sekar, Bellinger Andrew

Gene Therapy and the Potential LDL-Cholesterol "Cure"

Parikh Victoria, Knowles Josh, Khera Amit, Kathiresan Sekar

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