Scientific Sessions 2024  /  Best of AHA Specialty Conferences: EPI/Lifestyle 2024  /  Life-course socioeconomic status and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Logo

American Heart Association

  134
  0

Final ID: EPI12

Life-course socioeconomic status and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Abstract Body (Do not enter title and authors here): Introduction: Socioeconomic status (SES) in childhood and beyond may influence the gut microbiome (GMB), with implications for disease risk. Studies evaluating the relationship between life-course SES and the gut microbiome (GMB) are sparse, particularly among Hispanic/Latino individuals, who have a high prevalence of low SES.
Hypothesis: Low life-course SES indicators are associated with less diversity and overall composition of the gut microbiome in Hispanic/Latino adults.
Methods: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multi-site population-based cohort study conducted in the U.S. We examined 2540 participants (18 to 74 years) with SES and gut microbiome information. Childhood SES (n=2274) and adult SES (n=2412) were used as SES indicators. We used the highest education achieved by the father or mother and classified it as a lower (Results: Childhood and adult SES were not associated with the Shannon diversity index. Childhood and adult SES were associated with the overall gut microbiome composition; however, childhood SES explained more the gut microbiome variance than adult SES. Lower childhood SES was associated with 38 species and lower adult SES with 5 species. A lower childhood and adult SES were associated with a lower abundance of species from genus Bacteroides.
Conclusion: A lower childhood SES was associated with an altered GMB composition in U.S. Hispanic/Latino adults. Early-life SES may have long-term effects on GMB composition, underscoring another biological mechanism linking early childhood factors to adulthood disease.
  • Batalha, Monica  ( Albert Einstein College of Medicine , Bronx , New York , United States )
  • Lecroy, Madison  ( NYU Grossman School of Medicine , New York City , New York , United States )
  • Lin, Juan  ( Albert Einstein College of Medicine , Bronx , New York , United States )
  • Peters-samuelson, Brandilyn  ( Albert Einstein College of Medicine , Bronx , New York , United States )
  • Qi, Qibin  ( Albert Einstein College of Medicine , Bronx , New York , United States )
  • Wang, Zheng  ( Albert Einstein College of Medicine , Bronx , New York , United States )
  • Wang, Tao  ( Albert Einstein College of Medicine , Bronx , New York , United States )
  • Gallo, Linda  ( San Diego State University , San Diego , California , United States )
  • Talavera, Gregory  ( San Diego State University , San Diego , California , United States )
  • Mcclain, Amanda  ( San Diego State University , San Diego , California , United States )
  • Thyagarajan, Bharat  ( University of Minnesota , Minneapolis , Minnesota , United States )
  • Daviglus, Martha  ( University of Illinois at Chicago , Chicago , Illinois , United States )
  • Hou, Lifang  ( Northwestern University , Chicago , Illinois , United States )
  • Llabre, Maria  ( University of Miami , Miami , Florida , United States )
  • Cai, Jianwen  ( University of North Carolina at Chapel Hill , Chapel Hill , North Carolina , United States )
  • Kaplan, Robert  ( Albert Einstein College of Medicine , Bronx , New York , United States )
  • Isasi, Carmen  ( Albert Einstein College of Medicine , Bronx , New York , United States )
    • Author Disclosures:
    Monica Batalha: DO NOT have relevant financial relationships | Amanda McClain: DO NOT have relevant financial relationships | Bharat Thyagarajan: No Answer | Martha Daviglus: No Answer | Lifang Hou: No Answer | Maria Llabre: No Answer | Jianwen Cai: DO NOT have relevant financial relationships | Robert Kaplan: No Answer | Carmen Isasi: DO NOT have relevant financial relationships | Madison LeCroy: DO NOT have relevant financial relationships | Juan Lin: No Answer | Brandilyn Peters-Samuelson: DO NOT have relevant financial relationships | Qibin Qi: DO NOT have relevant financial relationships | Zheng Wang: No Answer | Tao Wang: DO NOT have relevant financial relationships | Linda Gallo: DO NOT have relevant financial relationships | Gregory Talavera: DO NOT have relevant financial relationships
Meeting Info:

Scientific Sessions 2024

2024

Chicago, Illinois

Session Info:

Best of AHA Specialty Conferences: EPI/Lifestyle 2024

Monday, 11/18/2024 , 10:30AM - 11:30AM

Best of Specialty Conferences

More abstracts on this topic:
Analysis of Community-Level High Blood Pressure Awareness Efforts for Philadelphia's Unhoused Population

Parikh Manav, Krishnan Aravind, Yuan Aurora, Bream Kent, Potluri Vishnu

Alloprevotella rava Alleviates Atherosclerosis through a secondary bile acid

Feng Weiqi, Feng Ruijia, Peng Guiyan, Long Ting, Yang Wenchao, Chang Guangqi, Huang Kan

More abstracts from these authors:
Non-genetic component of height as a surrogate marker for childhood socioeconomic status and its association with cardiovascular and brain health: results from HCHS/SOL

Moon Jee-young, Qi Qibin, Thyagarajan Bharat, Tarraf Wassim, Wang Tao, Isasi Carmen, Filigrana Paola, Gallo Linda, Perreira Krista, Cai Jianwen, Daviglus Martha, Fernandez-rhodes Lindsay, Garcia-bedoya Olga, Kaplan Robert

Intergenerational social mobility and cardiovascular health among caregivers and their offspring: results from the Study of Latino Youth (SOL Youth)

Batalha Monica, Isasi Carmen, Filigrana Paola, Perreira Krista, Mcclain Amanda, Pirzada Amber, Daviglus Martha, Cordero Christina, Delamater Alan, Gallo Linda

You have to be authorized to contact abstract author. Please, Login
Not Available