Abstract Body (Do not enter title and authors here): Introduction
Ventricular septal defect (VSD) is the most common pediatric defect which benefits from closure at an early age. This study describes the procedural and follow-up data from a 10-year experience of VSD device closure at a tertiary referral center in southern India.

Methods
We conducted a retrospective clinical data review of all pediatric patients who underwent transcatheter device closure for isolated VSD in the past ten years, from May 2014 to May 2024. We included patients with body weights less than 30 lbs. and excluded patients with VSD diameter >10mm and those with other congenital cardiac anomalies.

Results
We included 40 patients with a mean age of 18.95 ± 13.02 months, mean weight of 17.87 ± 6.64 lbs. and male:female ratio of 23:17 (Table 1). The most common symptom at presentation was failure to thrive (22, 55.0%), and five patients (12.5%) had VSD associated with Downs syndrome. 34 (85%) children had perimembranous VSD, and the rest had muscular VSD (6, 15.0%). The mean VSD size was 6.01 ± 2.29 mm, with a mean peak gradient of 49.55 ± 23.57 mm Hg. Either Amplatzer ADO II (14, 35.0%) or Lifetech Konar MF (26, 65.0%) devices were used, mainly via the retrograde approach (37, 92.5%) with a mean total fluoroscopy time of 21.82 ± 10.01 mins. Complications associated with the procedure were minimal (as in Table 2), with 77.5% (31 of 40) patients having no residual shunts at their follow-up ECHO after 6 months.

Conclusions
Transcatheter VSD device closure is a safe and effective procedure in young children weighing less than 30 lbs., with minimal complications and good outcomes at follow-up.